Recent Papers - Machine Learning Special Issue
Reviews/Accounts - last 5 years
Leishmaniasis is considered a complex disease. We propose a pipeline to select and analyze candidate targets and design inhibitory peptides, aiming to discover and investigate their binding sites for neglected tropical diseases based on the physicochemical properties of both peptides and target candidates. Details are presented in the Full Paper A Pipeline Protocol to Design, Discover and Research on Peptide Inhibitors and Binding Sites for Neglected Tropical Diseases: An Application for Leishmaniasis by Natanael E. S. M. T. Bonfim, Simone Q. Pantaleão, Leonardo A. Calderon, Eric Allison Philot and Ana Ligia Scott on e-20250023.
Natanael E. S. M. T. Bonfim ; Simone Q. Pantaleão
; Leonardo A. Calderon
; Eric Allison Philot
; Ana Ligia Scott
Leishmaniasis is considered a complex disease. We propose a pipeline to select and analyze candidate targets and design inhibitory peptides, aiming to discover and investigate their binding sites for neglected tropical diseases based on the physicochemical properties of both peptides and target candidates. Details are presented in the Full Paper A Pipeline Protocol to Design, Discover and Research on Peptide Inhibitors and Binding Sites for Neglected Tropical Diseases: An Application for Leishmaniasis by Natanael E. S. M. T. Bonfim, Simone Q. Pantaleão, Leonardo A. Calderon, Eric Allison Philot and Ana Ligia Scott on e-20250023.
Lívia C. R. M. da Frota ; Pedro P. de Castro
Flávia C. R. Costa ; Fábio S. L. Brito; Maria Júlia R. de Grandi; Juliana F. S. Daniel
A review of white rot fungi as a promising alternative for the treatment of industrial effluents containing dyes.
Gabriel S. Atarão ; Ana B. Viana
; Adrean A. Macedo; Taynara B. Riquiere
; Renan B. Pardinho
; Paula D. Vecchia
;
Valderi L. Dressler
Potassium is essential for plant growth and productivity, being necessary to control it in soil. Simple, low-cost, and portable methods for available potassium quantification in soil are required for a rapid response to decide on supply correct K doses.
Karoline M. Silva; David Douglas S. Fernandes ; Edilene D. T. Moreira
; Fernando G. P. Costa; Wellington S. Lyra
;
Paulo Henrique G. D. Diniz
A non-destructive, quick analytical method that employs a portable near-infrared (NIR) spectrophotometer and data-driven soft independent modeling of class analogy (DD-SIMCA) for freshness authentication of quail eggs under controlled storage conditions.
Xiao-Yan Xu; Ling-Feng Cao; Jian-Wu Xie
An effective domino vinylogous Michael-cyclization has been established for the synthesis of multifunctionalized cyclohexa-1,3-dienes with strong growth inhibition on Fusarium graminearum (F. graminearum).
Edson de O. Lima Filho ; Antônio Sérgio N. de Aguiar
; Leonardo Luiz Borges
; Vitor Francisco Ferreira
;
Fernando de C. da Silva
This work describes a new, simple, and green solvent- and metal-free method for the C-C bond formation reaction between sodium 1,2-naphthoquinone-4-sulfonate and tertiary anilines via mechanochemistry. Additionally, a computational study was carried out to investigate the mechanism.
Roger F. Baldissera ; Francielle Annunziato; Vicente Canalli; Marçal J. R. Pires
Formation of nitrogen contamination during ozone production in a dielectric barrier discharge (DBD) cell fed with wet air ambient.
Chrystiaine Helena C. de Matos; Paloma Carolina L. Carvalho; Alex O. Botelho; Moacir R. Forim ; Andreia P. Matos;
Gracielle O. S. Cunha ; Cássia Cristina F. Alves; Cristiane de M. Cazal
The influence of the circadian rhythm and hydrodistillation time on the content and chemical composition of the essential oils from the leaves of Callistemon viminalis was evaluated, as well as their antifungal activity.
Natanael E. S. M. T. Bonfim ; Simone Q. Pantaleão
; Leonardo A. Calderon
; Eric Allison Philot
; Ana Ligia Scott
In this work, we propose a protocol for identifying potential biological targets against Leishmaniasis, detecting their binding sites taking into account the flexibility of these proteins and their physicochemical characteristics for the appropriate coupling of bioactive peptides, thus helping with the treatment of Leishmaniasis.
Stefane S. Rodrigues; Sara L. Gomes; Yanka Manoelly S. Gaspar; Maria Carolina F. e Silva; Luciana B. Silva; Sidney G. de Lima ; Welter Cantanhêde; Francisca Diana S. Araújo
Nanoemulsions based on Piper tuberculatum essential oil showed toxicity against the crop pest Bemisia tabaci similar to the commercial insecticide.
Wenbi Guan ; Hengrui Lian; Yunjin Cai; Su Yao; Hongwu Wang
Nanosized γ-aluminum oxide was used as effective dispersive solid-phase extraction sorbent to pesticides multi-residue analysis in cereal grains by gas chromatography-orbitrap mass spectrometry analysis.
Lu Wang; Shuang Tian; Qiang Lin; Yu Lin ; Yukun Ma; Ran Luo; Ming Bu
; Haijun Wang
Design, synthesis and biological evaluation of compound 9c: a novel glutaminase 1 inhibitor.
Caroline N. Benetti ; Patrícia L. Weinert; José M. Aquino; Elaine R. L. Tiburtius
The heterogeneous photocatalysis process, involving a combination of semiconductors, maximizes the efficiency of dye removal in aqueous solution.
Júnio G. Silva ; Leonardo L. Okumura
; Flávia A. Pinheiro; Astréa F. S. Silva; Edimar A. F. Fontes; Juliana A. Diniz
This voltammetric study on 14 food matrices explored the different parameters using different extraction media and techniques. The results elucidate the electrochemical behavior of the matrices under different analytical conditions and indicate the presence of antioxidant compounds in all analyzed samples.
Kelline Alaide P. Sousa; Camila S. de Sousa; Franciele M. Morawski; Antonio G. dos Santos Neto; Cristiane Luisa Jost
Promising tool for the electroanalysis of coexisting contaminants like isoproturon (ISO) and para-nitrophenol (p-NP) in environmental samples. Square wave voltammetry and glassy carbon electrode guarantee the simultaneous determination with accuracy and proper selectivity.
Marta Luciane Fischer; Eduardo N. Ramires; Carlos Delay; Gustavo Frensch ; Stefan Schulz; Emanuel M. da Silva;
Beatriz H. L. N. S. Maia; Francisco A. Marques
Geranyl acetone and geranyl acetate, produced exclusively by female Loxosceles intermedia recluse spiders, of medical interest, have been found to be more attractive to males compared to females.
João Victor Silva-Silva ; André O. Feitosa; Thiago Henrique Doring; Luciano A. Watanabe; José Edson S. Siqueira;
Adriano D. Andricopulo; Patrícia S. B. Marinho; Andrey Moacir R. Marinho
Aflavinine alkaloids from Aspergillus sp. show potential as Gram-positive bacterial inhibitors, possibly targeting Bacillus inosine-5'-monophosphate dehydrogenase (IMPDH), as indicated by docking, dynamics, and density functional theory (DFT) analyses.
Fernanda R. dos Passos; Mônica L. Fiorese; Edson A. da Silva; Oscar O. Santos Jr.; Lúcio Cardozo Filho; Camila da Silva
Extraction of active compounds from Pereskia aculeate leaf.
Tayná S. Picanço; Maria Clara R. de Souza; Ana Paula S. Figueiredo; Roberta C. Urban; Benigno S. Cabrero; Maria Cristina Canela ; Murilo O. Souza
Tropospheric ozone (O3) formation in Itaperuna-RJ, is driven by the hot climate, pollutant-trapping valleys, and BTEX (benzene, toluene, ethylbenzene, and xylenes) emissions, posing health and climate risks.
Glauco Cézar F. F. Soares; Danillo F. M. C. Veloso ; Iram M. Mundim; Leonardo S. Teixeira; Maria Carolina Almeida
;
Luiz Carlos da Cunha
Lamotrigine pharmacokinetics was assessed using an ultrafast laser diode thermal desorption coupled with mass spectrometry (LDTD-MS/MS) method, which bypasses high-performance liquid chromatography (HPLC) separation and provides reliable results in 10 s per sample.
Erica R. Costa; Eduardo J. Coutinho; Jaqueline C. M. da Silva; Janaina T. Facco; Márcia S. M. Vaz; Simone Simionatto;
Cláudia A. L. Cardoso; Michele C. de Paula‑Silva; Euclésio Simionatto
The chemical composition of essential oils isolated from the species Cinnamomum verum and Ocotea catharinensis (Lauraceae) was characterized, followed by evaluations of activity against multidrug-resistant (MDR) bacteria and seasonal effects.
Mustapha N. Abubakar ; Vitor S. Mazucato
; Paulo C. Vieira
The phytophatogenic fungus Colletotrichum gloeosporioides, isolated from papaya, cultured on potato dextrose agar (PDA), subsequently up-scaled in rice medium, produced new derivatives of colletotricandins 2 and 3 as well as thielavins 4 and 5, along with other known metbolites.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access