JBCS

9:39, Sun Dec 17

Open Access/APCs

The JBCS Office will be closed from Dec 23, 2017 to Jan 2, 2018
Non-stopping MS submission process and correspondence receiving
(to be processed in the return on Jan 3, 2018)

Current Issue vol. 29, No. 2, 2018, p. 217-434

 

Antimicrobial resistance is a global concern because is present in every country. Bacterial biofilm is associated with many persistent infections and increased resistance to antibiotics. Diguanylate cyclase enzymes (DGC) are an attractive target for antibiofilm drug intervention. Drug repurposing strategy resulted in DGC inhibitors discovery from therapeutics drugs using the integration of computational and biochemical assays. Details are presented in the Article Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases by Helton J. Wiggers, Édson Crusca, Éverton E. D. Silva, Juliana Cheleski, Naiara U. Torres and Marcos V. A. S. Navarro on page 297.


Cover Article
J. Braz. Chem. Soc. 2018, 29(2), 297-309

Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases

Helton J. Wiggers; Edson Crusca; Éverton E. D. Silva; Juliana Cheleski; Naiara U. Torres; Marcos V. A. S. Navarro

How to cite this article

Antimicrobial resistance is a global concern because is present in every country. Bacterial biofilm is associated with many persistent infections and increased resistance to antibiotics. Diguanylate cyclase enzymes (DGC) are an attractive target for antibiofilm drug intervention. Drug repurposing strategy resulted in DGC inhibitors discovery from therapeutics drugs using the integration of computational and biochemical assays. Details are presented in the Article Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases by Helton J. Wiggers, Édson Crusca, Éverton E. D. Silva, Juliana Cheleski, Naiara U. Torres and Marcos V. A. S. Navarro on page 297.

http://dx.doi.org/10.21577/0103-5053.20170141

Published online: July 24, 2017

Articles J. Braz. Chem. Soc. 2018, 29(2), 217-225

Synthesis and Application of Bimetallic Zinc(II) Phenoxy-Imine Complexes as Initiators for Production of Lactide Polymers

Alana L. C. Oliveira; Leonardo C. Ferreira; Marcos L. Dias; Rodrigo S. Bitzer; Marco A. C. Nascimento; Maria de Fátima V. Marques; Laura Crociani

How to cite this article

 

Bimetallic ZnII complexes with phenoxy-imine ligands were synthesized and used as initiators for lactide polymerization.

http://dx.doi.org/10.21577/0103-5053.20170131

Published online: July 10, 2017

J. Braz. Chem. Soc. 2018, 29(2), 226-231

Nanoporous Gold Surface: An Efficient Platform for Hydrogen Evolution Reaction at Very Low Overpotential

Anandhakumar Sukeri; Mauro Bertotti

How to cite this article

 

A nanostructured porous gold based electrocatalyst was fabricated via a facile electrochemical approach and an excellent activity with good stability for hydrogen evolution reaction was noticed.

http://dx.doi.org/10.21577/0103-5053.20170132

Published online: July 10, 2017


J. Braz. Chem. Soc. 2018, 29(2), 232-239

A Novel Electrochemical Aptamer Biosensor Based on DNAzyme Decorated Au@Ag Core-Shell Nanoparticles for Hg2+ Determination

Yanling Zhao; Xianmei Xie

How to cite this article

 

Based on thymine-Hg2+-thymine binding mode (T-Hg2+-T), a sensitive aptamer biosensor was constructed by utilizing functionalized Au@Ag core-shell nanoparticles as labels for detection of Hg2+.

http://dx.doi.org/10.21577/0103-5053.20170133

Published online: July 11, 2017

J. Braz. Chem. Soc. 2018, 29(2), 240-247

Binary Blends of Biodiesel from Macauba (Acromia aculeata) Kernel Oil with Other Biodiesels

Willian L. G. da Silva; Acacia A. Salomão; Patricia T. de Souza; Marina Ansolin; Matthieu Tubino

How to cite this article

 

The oil from the kernel of macauba presents high stability to oxidation, property that is transferred to its biodiesel, which also presents low cold filter plugging point. Such properties are inherited by its blends with biodiesels obtained from other vegetable oils.

http://dx.doi.org/10.21577/0103-5053.20170134

Published online: July 13, 2017

J. Braz. Chem. Soc. 2018, 29(2), 248-257

Evaluation of Crocins in Cheeses Made with Saffron by UHPLC

Mena Ritota; Maria Mattera; Maria Gabriella Di Costanzo; Pamela Manzi

How to cite this article

 

Cheeses made with saffron are expected to provide an added value for consumers, due to saffron bioactive compounds. This UHPLC method seems to be useful to detect saffron crocins in dairy products.

http://dx.doi.org/10.21577/0103-5053.20170135

Published online: July 13, 2017

J. Braz. Chem. Soc. 2018, 29(2), 258-268

Hirshfeld Surfaces and Nonlinear Optics on Two Conformers of a Heterocyclic Chalcone

Jean M. F. Custodio; Cauã A. Moreira; Clodoaldo Valverde; Gilberto L. B. de Aquino; Basílio Baseia; Hamilton B. Napolitano

How to cite this article

 

The nature of crystal packing of an heterocyclic chalcone, investigated by Hirshfeld surfaces, and its potential nonlinear optical properties.

http://dx.doi.org/10.21577/0103-5053.20170136

Published online: July 13, 2017

J. Braz. Chem. Soc. 2018, 29(2), 269-277

Synthesis of 3,5-Diarylisoxazole Derivatives and Evaluation of in vitro Trypanocidal Activity

Aline A. N. de Souza; Viviane F. Xavier; Gleicekelly S. Coelho; Policarpo A. Sales Junior; Alvaro J. Romanha; Silvane M. F. Murta; Claudia M. Carneiro; Jason G. Taylor

How to cite this article

 

A series of novel substituted isoxazoles were prepared and tested for in vitro anti T. cruzi activity. The lead compound is equally as potent as reference drug benzonidazole.

http://dx.doi.org/10.21577/0103-5053.20170137

Published online: July 13, 2017


J. Braz. Chem. Soc. 2018, 29(2), 278-284

Use of Amphiphilic Composites based on Clay/Carbon Nanofibers as Fillers in UHMWPE

Claudilene R. Silva; Rochel M. Lago; Helena S. Veloso; Patrícia S. O. Patricio

How to cite this article

 

The more efficient interaction of the fillers based on hydrophobic surface nanostructures with the hydrophobic UHMWPE chains leading to a much higher dispersion of the filler particles throughout the polymeric matrix.

http://dx.doi.org/10.21577/0103-5053.20170138

Published online: July 14, 2017


J. Braz. Chem. Soc. 2018, 29(2), 285-296

Evaluation of the Concentration of Cu, Zn, Pb and Cr in Different Fish Species from the São Gonçalo Channel in Pelotas-RS, Brazil

Marcelo M. Alves; Aline L. Medina; Ane Martiele T. Pinto; Ana Clara N. Antunes; Pedro José Sanches Filho; Anderson S. Ribeiro; Mariana A. Vieira

How to cite this article

 

The concentration of Cu, Zn, Cr and Pb in different species of fish collected in the estuarine and limnic regions of the São Gonçalo channel in Pelotas City were determined.

http://dx.doi.org/10.21577/0103-5053.20170139

Published online: July 18, 2017


J. Braz. Chem. Soc. 2018, 29(2), 297-309

Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases

Helton J. Wiggers; Edson Crusca; Éverton E. D. Silva; Juliana Cheleski; Naiara U. Torres; Marcos V. A. S. Navarro

How to cite this article

 

Virtual screening applied to FDA-approved drugs allowed the inhibitor discovery for enzymes diguanylate ciclases involved in the bacterial biofilm formation.

http://dx.doi.org/10.21577/0103-5053.20170141

Published online: July 24, 2017

J. Braz. Chem. Soc. 2018, 29(2), 310-319

Surface Imprinting of Silica Gel by Methyldopa and Its Application in the Solid Phase Extraction Procedure

Mohammad Taghi Vardini; Leila Mardani

How to cite this article

 

Surface of the activated silica gel was grafted with the complex of MTD-APS. The custom made holes to the MTD remain on the surface of molecularly imprinted adsorbent.

http://dx.doi.org/10.21577/0103-5053.20170142

Published online: July 24, 2017

J. Braz. Chem. Soc. 2018, 29(2), 320-327

Functionalization of Bentonite and Vermiculite after the Creation of Structural Defects through an Acid Leaching Process

Dorsan S. Moraes; Lucas C. R. Miranda; Rômulo S. Angélica; Geraldo N. Rocha Filho; José R. Zamian

How to cite this article

 

Schematic model of a 2:1 layer structure of the organofunctionalized materials present in this work, suggesting the superficial acid sites created.

http://dx.doi.org/10.21577/0103-5053.20170143

Published online: July 31, 2017

J. Braz. Chem. Soc. 2018, 29(2), 328-333

SBA-15 as a Support for Nickel-Based Catalysts for Polymerization Reactions

Anderson J. Schwanke; Cristiano Favero; Rosana Balzer; Katia Bernardo-Gusmão; Sibele B. C. Pergher

How to cite this article

 

Polymerization reaction with a nickel-based catalyst supported on SBA-15 mesoporous materials.

http://dx.doi.org/10.21577/0103-5053.20170144

Published online: August 1, 2017

J. Braz. Chem. Soc. 2018, 29(2), 334-342

Preparation of Tetraethylenepentamine Modified Magnetic Graphene Oxide for Adsorption of Dyes from Aqueous Solution

Xiaosheng Tang; Ping Tang; Liangliang Liu

How to cite this article

 

Tetraethylenepentamine modified magnetic graphene oxide nanomaterial was prepared and it had a good adsorption ability to remove dyes in wastewater.

http://dx.doi.org/10.21577/0103-5053.20170145

Published online: August 2, 2017

J. Braz. Chem. Soc. 2018, 29(2), 343-352

Synthesis, Antioxidant Activity, Acetylcholinesterase Inhibition and Quantum Studies of Thiosemicarbazones

Larissa Sens; Aldo S. de Oliveira; Alessandra Mascarello; Inês M. C. Brighente; Rosendo A. Yunes; Ricardo J. Nunes

How to cite this article

 

The current study investigated the antioxidant activity, acetylcholinesterase inhibition and quantum studies of thiosemicarbazones.

http://dx.doi.org/10.21577/0103-5053.20170146

Published online: August 4, 2017


J. Braz. Chem. Soc. 2018, 29(2), 353-362

Alkaline Solubilization of Chicken Tissues Monitored by Raman Spectroscopy Followed by Pb Determination by GF AAS

Náira S. Campos; Marcone A. L. de Oliveira; Celly M. S. Izumi; Rafael A. de Sousa

How to cite this article

 

Lead content was evaluated in chicken viscera by GF AAS after solubilization with tetramethylammonium hydroxide (TMAH). Sample preparation was monitored by Raman spectroscopy and SEM-EDS.

http://dx.doi.org/10.21577/0103-5053.20170148

Published online: August 16, 2017


J. Braz. Chem. Soc. 2018, 29(2), 363-370

Morpho/Proteomic Comparative between High Grade Pleomorphic Sarcoma and Metastasis Diagnosed in an Old Captive Common Hippo

Adriana R. Silva; José T. J. G de Lacerda; Bernadete Faria; Isabela W. da Cunha; Vitor P. de Andrade; Nilson A. Assunção

How to cite this article

 

Mass spectrometry analysis as additional tool for description and differentiation of tumor physiopathology: a comparative proteomic study between pheomorphic sarcoma, metastasis and healthy tissues.

http://dx.doi.org/10.21577/0103-5053.20170149

Published online: August 17, 2017


J. Braz. Chem. Soc. 2018, 29(2), 371-379

Effect of Selenite and Selenate Application on Mineral Composition of Lettuce Plants Cultivated Under Hydroponic Conditions: Nutritional Balance Overview Using a Multifaceted Study

Emanueli do Nascimento da Silva; Mirla Cidade; Gabriel Heerdt; Rafael L. Ribessi; Nelson H. Morgon; Solange Cadore

How to cite this article

 

Selenate and selenite enrichment in the Veneza Roxa lettuce was carried out and the mineral composition was evaluated using ICP OES, PCA and molecular modeling. Selenate-biofortified lettuce showed a synergetic effect with S and Mo while selenite-biofortified lettuce showed a synergetic effect with Mn, P, Mg and Ca.

http://dx.doi.org/10.21577/0103-5053.20170150

Published online: August 17, 2017

J. Braz. Chem. Soc. 2018, 29(2), 380-389

Suspended and Immobilized TiO2 Photocatalytic Degradation of Estrogens: Potential for Application in Wastewater Treatment Processes

Marcus V. de Liz; Rubia M. de Lima; Bianca do Amaral; Belisa A. Marinho; Jessica T. Schneider; Noemi Nagata; Patricio Peralta-Zamora

How to cite this article

 

Photocatalytic degradation of estrogens by suspended and immobilized TiO2 were compared in aqueous and wastewater samples. The EE2 degradation products were monitored by GC-MS/MS.

http://dx.doi.org/10.21577/0103-5053.20170151

Published online: August 24, 2017

J. Braz. Chem. Soc. 2018, 29(2), 390-397

Comparative Study of the Lipid Profiles of Oils from Kernels of Peanut, Babassu, Coconut, Castor and Grape by GC-FID and Raman Spectroscopy

William S. Martini; Brenda L. S. Porto; Marcone A. L. de Oliveira; Antonio C. Sant'Ana

How to cite this article

 

A fast evaluation of the degree of unsaturation and the presence of oxidized products in oil samples by Raman spectroscopy, through the identification of marker bands, assigned by supporting of GC-FID analyses of standard fatty acids.

http://dx.doi.org/10.21577/0103-5053.20170152

Published online: August 24, 2017

J. Braz. Chem. Soc. 2018, 29(2), 398-403

Absolute Configuration of Solenopsis Piperidines is a Tool to Classify Fire Ants (Formicidae:Myrmicinae)

Francisca D. S. Araújo; Marcela A. Botelho; José R. Trigo; Anita J. Marsaioli

How to cite this article

 

Chiral GC chromatogram of the peak discrimination of 2-methyl-6-undecylpiperidine trifluoroacetamide stereoisomers (synthetic standard mixture).

http://dx.doi.org/10.21577/0103-5053.20170153

Published online: August 24, 2017


J. Braz. Chem. Soc. 2018, 29(2), 404-411

Thermal Properties and Kinetics of Al/α-MnO2 Nanostructure Thermite

Jia-Xing Song; Xiang Fang; Tao Guo; Feng-Li Bei; Wen Ding; Xiao-Nan Zhang; Miao Yao; Hong-Jun Yu

How to cite this article

 

Thermal properties and kinetics of Al/α-MnO2 nanostructure thermite was reported in this work. According to DSC curves, the heat release and onset temperature were measured. Then the changes of activation energy on extent of conversion (α) for kinetics of Al/α-MnO2 thermite were obtained by using isoconversional method.

http://dx.doi.org/10.21577/0103-5053.20170154

Published online: August 29, 2017

J. Braz. Chem. Soc. 2018, 29(2), 412-418

Catalytic Behaviors of CoII and MnII Compounds Bearing α-Diimine Ligands for Oxidative Polymerization or Drying Oils

Gilvan E. S. Lima; Everton V. Nunes; Roberta C. Dantas; Carlos A. de Simone; Mario R. Meneghetti; Simoni M. P. Meneghetti

How to cite this article

 

Metal carboxylate complex modified with nitrogen ligands used as catalyst to oxidative polymerization of drying oils.

http://dx.doi.org/10.21577/0103-5053.20170155

Published online: August 29, 2017


J. Braz. Chem. Soc. 2018, 29(2), 419-429

Enantiomeric Ratio Changes of Terpenes in Essential Oils from Hybrid Eucalyptus grandis × E. tereticornis and its Pure Species

Cecilia Naspi; Agustín A. Costa; Alejandro Lucia; Paola G. Audino; Hector M. Masuh

How to cite this article

 

Fractionation of essential oils from Eucalyptus grandis × E. tereticornis, and its parental taxa, by HPLC followed by GC-MS analysis using two columns in series, allowed to determinate the enantiomeric excesses of selected monoterpenes. Significant differences were found in the enantiomeric ratios in monoterpene alcohols between the three essential oils.

http://dx.doi.org/10.21577/0103-5053.20170156

Published online: August 31, 2017

Short Report J. Braz. Chem. Soc. 2018, 29(2), 430-434

Fast Screening of Solvents for Simultaneous Extraction of Furfural, 5-Hydroxymethylfurfural and Levulinic Acid from Aqueous Solution Using SMD Solvation Free Energies

Ellen V. Dalessandro; Josefredo R. Pliego Jr.

How to cite this article

 

Automated computational screening of 178 solvents for extraction of organic chemicals from aqueous phase.

http://dx.doi.org/10.21577/0103-5053.20170140

Published online: July 20, 2017

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
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