This robotic system combines open-source hardware and 3D printing to democratize automated liquid handling. It integrates colorimetric and electrochemical detection for multi-analyte quantification (e.g., glucose, nitrite, phosphate) with minimal user intervention, serving environmental, agricultural, and biological applications. Modular and cost-effective, it pioneers self-operating laboratories in resource-limited regions. Details are presented in the Full Paper 3D-Printed Liquid Handling Robot for the Development of Automated Analytical Methods by Aline D. Assunção, Diogo M. de Jesus, Teodoro R. Terra, Raquel G. Rocha, José A. M. G. Costa, Luiz A. J. da Silva, Guilherme L. Fernandes, Alessandro G. C. Dias, Rodrigo A. A. Muñoz, Sidnei G. Silva and Eduardo M. Richter on e-20250114.
Aline D. Assunção ; Diogo M. de Jesus
; Teodoro R. Terra; Raquel G. Rocha
; José A. M. G. Costa; Luiz A. J. da Silva;
Guilherme L. Fernandes; Alessandro G. C. Dias; Rodrigo A. A. Muñoz ; Sidnei G. Silva
; Eduardo M. Richter
This robotic system combines open-source hardware and 3D printing to democratize automated liquid handling. It integrates colorimetric and electrochemical detection for multi-analyte quantification (e.g., glucose, nitrite, phosphate) with minimal user intervention, serving environmental, agricultural, and biological applications. Modular and cost-effective, it pioneers self-operating laboratories in resource-limited regions. Details are presented in the Full Paper 3D-Printed Liquid Handling Robot for the Development of Automated Analytical Methods by Aline D. Assunção, Diogo M. de Jesus, Teodoro R. Terra, Raquel G. Rocha, José A. M. G. Costa, Luiz A. J. da Silva, Guilherme L. Fernandes, Alessandro G. C. Dias, Rodrigo A. A. Muñoz, Sidnei G. Silva and Eduardo M. Richter on e-20250114.
Angélica G. Oliveira ; Glaucio José Gomes
; Lucas Spessato
; Paulo Rodrigo S. Bittencourt
; Janine C. Padilha
;
Caroline C. S. Gonçalves
Cigarette filters were pyrolyzed to obtain bio-oil and biochar aiming at efficient CO2 adsorption.
Lucas D. P. Gonçalves ; Deborah A. Simoni
; Emilio C. de Lucca Jr.
Through a two-step deoxygenative olefination approach, we synthesized three stachene natural products from isosteviol, including the first reported synthesis of (+)-nidoanomalin.
Mariana T. C. Campos ; Vinícius R. D. Pereira
; Geovana F. Vargas; Maira G. R. Pitta
; Breno C. de Araujo
;
Luiz F. C. de Oliveira ; Giovanni W. Amarante
The figure illustrates the in situ Raman spectroscopic monitoring of the Vilsmeier-Haack cyanation of pyrrole and indole. The visual flow represents the progression of the reaction through substrates, intermediates, and finally, the products, with Raman spectra evidencing the molecular transformations.
Lara Fábia M. Oliveira ; Weida R. Silva
; João Flávio da Silveira Petruci
The synthesis of molecularly imprinted polymers (MIPs) for scopolamine via bulk polymerization, combined with a 3D-printed device, aims to remove the drug from contaminated drinks, thereby preventing unwanted ingestion and potential crimes facilitated by the drug.
José C. I. Silva ; Felipe M. A. Silva
; Gilvan F. Silva
; Hector H. F. Koolen
A comprehensive review of the chemistry and biological activities of koningins and related fungal octaketides.
Matheus C. Castro; Eloize S. Alves; Bruno H. F. Saqueti; Cintia Stefhany R. Ferreira; Joana M. V. Zacarias; Jeane E. L. Visentainer; Francieli S. O. Trombelli; Sueli M. T. Ichisato; Oscar O. Santos ; Jesui V. Visentainer
Study of the energy content, fatty acid composition and cytokines tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) content in mature human milk at different breastfeeding intervals (foremilk, middle milk, and hindmilk).
Luíza M. de Macêdo; Quezia V. F. S. da Fonseca; Iris C. dos Santos; Quézia L. S. Sampaio; Janine F. S. Silva; Moyses F. de Araujo Neto; Aníbal F. Santos Júnior ; Erika M. O. Ribeiro; Franco H. A. Leite; Humberto F. de Freitas
; Samuel S. R. Pita
; André L. B. Teles
Flowchart summarizing the steps used to conduct virtual screening and identify potential selective inhibitors of Leishmania chagasi dihydrofolate reductase-thymidylate synthase (LcDHFR-TS).
Stamber A. Ramírez-Revilla ; Oscar A. Serrano Ollancaya
; Gustavo E. F. Vilcapaza Condori
; Derly D. Ortiz-Romero
Application of ultrasound and conventional methods to alpaca fibers, demonstrating the absorption of the dyes Synozol Red K3BS and Novacron Navy FN-BN.
Wellerson Wagner B. Silva ; Luiz Fernando S. Novaes
; Luiz Henrique C. Adriano
; Naiara Norberto T. de Oliveira
;
Wilson R. Braz ; Paula R. Chellini
; Marcone Augusto L. de Oliveira
A method was developed and validated, by the application of 32 factorial, for the monitoring of azithomycin (AZM) and its impurities.
Jorge Luiz dos Santos; Iterlandes Machado Junior; Gabriel Henrique Sperandio; Gessica do C. Dias; Anderson Dias;
Geraldo M. de Lima; Renata P. L. Moreira
The platinum nanoparticles (Pt NPs)/MnWO4 composite was synthesized and showed to be an efficient, reusable catalyst for H2 generation via NaBH4 hydrolysis.
Aline D. Assunção ; Diogo M. de Jesus
; Teodoro R. Terra; Raquel G. Rocha
; José A. M. G. Costa; Luiz A. J. da Silva;
Guilherme L. Fernandes; Alessandro G. C. Dias; Rodrigo A. A. Muñoz ; Sidnei G. Silva
; Eduardo M. Richter
A low-cost, 3D-printed liquid handling robot enables autonomous calibration, precise analytical management, and advanced flow analysis, integrating electrochemical and colorimetric detection for unprecedented automation.
Total access: 583
Charles-Oneil L. Crites ; José Carlos Netto-Ferreira; Geniece L. Hallett-Tapley; Samuel Banville; Luc Tremblay
Lignin depolymerization was done using an Au/Pd@TiO2 via three subsequent reactions (alcohol oxidation, photo-cleavage and hydrogenolysis) under light irradiation (UV or green light).
Paulo Roberto dos Santos ; Manuela Merlin
; Fávero R. Paula
; Sidnei Moura
This study highlights the importance of combining in silico analysis with experimental techniques, emphasizing the need for careful handling of simvastatin, particularly concerning the formation of hydrolysis products, oxidation, and light exposure.
Jennifer A. O. Lima; Helena G. Ramos; Junior A. Chaves; Claudete C. do Nascimento; Luiz Henrique K. Queiroz-Junior;
Danielle F. da Silva; Jéssica Cristina Amaral; Maria Fátima das Graças F. da Silva ; Maria da Paz Lima
Phytochemical study of Ocotea neesiana demolition wood led to the purification of eight compounds. The sesquiterpene α-cadinol and the diterpene 16-methylesteritol A exhibited antibacterial potential against Xanthomonas citri subsp. citri.
Laís T. de Marco; Fernando A. de Oliveira; Karine Panico; Anabella P. Rosso; Michelle Nascimento-Sales; Mariana M. R. Andrade; Marcelo A. Christoffolete; Lidiane Meier; Ismael C. Bellettini ; Fernando C. Giacomelli
Amino acid-modified branched polyethyleneimines enable safer and more efficient deoxyribonucleic acid (DNA) delivery via polyplex formation, offering novel possibilities, including ocular gene therapy.
Amanda C. O. D. Barros ; Ivo D. L. Silva; Adriano N. Simões; José F. Q. Pereira
; Andréa M. S. S. Brito
; Glória M. Vinhas
Representation of the bacterial cellulose (BC) production process using pulp juice from Cereus jamacaru DC fruit fermented with Komagataeibacter hansenii. The steps include the raw fruit, preparation of the medium, and the wet and dry forms of BC.
Pedro Victor A. Pessanha ; Antonio Carlos Sant'Ana
Probing tailored interactions between doxorubicin and surface modified gold nanoparticles by surface-enhanced Raman scattering (SERS) spectroscopy.
Thiago F. da Costa ; Otavio M. Sobrinho
; Amanda Karine C. Ribeiro
; Angie Natali Z. Ovalle
; Rizzieri Pedruzzi
;
Taciana T. A. Albuquerque ; Eduardo M. Martins
Analysis of input files from Atmospheric Global Emission Inventory in the State of Rio de Janeiro.
Nouhaila Gadda ; Khalid Bouiti
; Najoua Labjar
; Youssra El Hamdouni
; Najoua Souad Lagmiri
; Hamid Nasrellah
;
Ayoub Cherrat ; Ghita Amine Benabdallah; Houda Labjar; Souad El Hajjaji
Chamaerops humilis fruit pulp was hydrothermally carbonized and subsequently activated by H3PO4 to perform Methylene Blue adsorption using hydrochar-activated carbon (CHHAC). Material characterization (scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR)), adsorption experiments, and response surface methodology (RSM) modeling were carried out to optimize conditions, determine performance, and evaluate reusability.
Vinicius Kuchenbecker ; Cleverson Rogério Princival
; Edson Katekawa
; Wagner V. Magalhães
; Aparecido Junior de Menezes
A novel polytrimethylene ether glycol (PO3G) oligomer microwave assisted synthesis with attenuated total reflectance Fourier transformed infrared (ATR-FTIR) reaction monitoring, moving forward into the green chemistry.
Marília S. Souza ; Rodrigo G. Agostinho
; Mariana dos S. Dupim
; Rodrigo O. M. A. de Souza
; Karen C. C. Machado
;
Wagner Wollinger ; Eliane C. P. do Rego
; Fernanda G. Finelli
This study developed a Brazilian amphetamine hydrochloride certified reference material to support forensic analyses, in partnership with the University, Institute of Metrology, Quality and Technology (Inmetro), and the Federal Police.
In silico analysis suggests that soy isoflavonoids such as 8-hydroxydaidzein and dihydrogenistein may inhibit androgen receptor signaling in prostate cancer, requiring further research.
Evelyn D. Pereira ; Daniel V. Cardoso
; Márcia R. Fagundes-Klen
; Carina C. Triques
; Ricardo F. Zara
; Jaqueline Hoscheid
; Erica Camila Pavan
; Edson A. da Silva
Nonconventional extraction techniques, ultrasound-assisted and pressurized liquid extractions were compared to dynamic maceration, using ethanol as the solvent, to extract antioxidant compounds, especially ascorbic acid, from camu-camu fruits.
Moysés B. de Araújo Júnior ; Aline O. Santos
; Aline M. Rodrigues
; Thiago F. Sousa
; Felipe M. A. da Silva
;
Célio F. F. Angolini ; Renan S. Galaverna
; Lívia S. de Medeiros
; Fabiana E. Casarin
; Michel E. B. Yamagishi
;
Gilvan F. Silva ; Hector H. F. Koolen
The integrated approach of genome mining with mass spectrometry sheds light on the biosynthesis pathway of oosporein (OOS) and analogous compounds in the culture of Arcopilus amazonicus.
Jonatas M. Negreiro ; José A. C. Oliveira
; Fátima M. Nunes
; Francisco G. Barbosa
; Jair Mafezoli
; Marcos C. Mattos
; Danielle S. Macedo
; Geancarlo Zanatta
; Maria C. F. Oliveira
A multi-step in silico pipeline was used to screen 821 lanostane triterpenes against the N-methyl-D-aspartate (NMDA) receptor, identifying three lead candidates with high affinity and potential as fast-acting antidepressants.
Cloé D. Loredo ; Giovana P. Peteffi; Camila F. de Souza; Roberta Z. Hahn; Ana Paula Grando; Giovanna S. Grassi; Marina V. Antunes; Rafael Linden
A new method for determination of parabens in urine samples using solid phase extraction followed by liquid chromatography-tandem mass spectrometry (LC/MS-MS) analysis.
Andreza A. de Souza ; Leonis L. da Luz
; Dayane K. D. N. Santos
; Dominique C. A. Dias
; Rodrigo J. de Oliveira
;
Severino Alves Júnior
Eu3+-based hybrid responsive to chemical and physical stimuli under UV light as an alternative in the security area.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
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