Current Issue vol. 36, No. 10, 2025
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A glowing brain cross-section and a zebrafish symbolize model organisms in neurological research. The dark and viscous cashew nut shell liquid (CNSL) drips and transforms into golden spheres with an organic coating, representing silver nanoparticles, which travel toward the stylized GABAA receptor embedded in the cell membrane. Bright yellow dots highlight the primary binding sites of the receptor. Details are presented in the Article In vivo and in silico Evaluation of Cashew Nut Shell Liquid and Ag-CNSL Nanoparticles for Anxiolytic Activity in Zebrafish via GABAergic Pathways by Thayllan T. Bezerra, Mayara O. Almeida, Pergentino N. Maia Júnior, Emerson Y. A. Sousa, Maria K. A. Ferreira, Antonio W. Silva, Giuseppe Mele, Emmanuel S. Marinho, Hélcio S. Santos, Jane E. S. A. Menezes, Diego Lomonaco and Selma E. Mazzetto on e-20250103.
In vivo and in silico Evaluation of Cashew Nut Shell Liquid and Ag-CNSL Nanoparticles for Anxiolytic Activity in Zebrafish via GABAergic Pathways
Thayllan T. Bezerra 
; Mayara O. Almeida ; Pergentino N. Maia Júnior ; Emerson Y. A. Sousa ; Maria K. A. Ferreira ;
Antonio W. Silva ; Giuseppe Mele ; Emmanuel S. Marinho ; Hélcio S. Santos ; Jane E. S. A. Menezes ; Diego Lomonaco ; Selma E. Mazzetto
A glowing brain cross-section and a zebrafish symbolize model organisms in neurological research. The dark and viscous cashew nut shell liquid (CNSL) drips and transforms into golden spheres with an organic coating, representing silver nanoparticles, which travel toward the stylized GABAA receptor embedded in the cell membrane. Bright yellow dots highlight the primary binding sites of the receptor. Details are presented in the Article In vivo and in silico Evaluation of Cashew Nut Shell Liquid and Ag-CNSL Nanoparticles for Anxiolytic Activity in Zebrafish via GABAergic Pathways by Thayllan T. Bezerra, Mayara O. Almeida, Pergentino N. Maia Júnior, Emerson Y. A. Sousa, Maria K. A. Ferreira, Antonio W. Silva, Giuseppe Mele, Emmanuel S. Marinho, Hélcio S. Santos, Jane E. S. A. Menezes, Diego Lomonaco and Selma E. Mazzetto on e-20250103.
https://dx.doi.org/10.21577/0103-5053.20250103
Editorial J. Braz. Chem. Soc. 2025, 36(10), e-20250133, 1-3
The Science-Inducing Role of the JBCS for the Chemistry Scenario of the Brazilian Central-West Region
Cristiane S. Schwalm ; Angelo H. L. Machado
https://dx.doi.org/10.21577/0103-5053.20250133
Review J. Braz. Chem. Soc. 2025, 36(10), e-20250096, 1-17
New Advancements in Production, Purification, and Current Biological Activities of Violacein
Nelson Durán ; Wagner J. Fávaro ; Symone C. de Castro ; Gerson Nakazato ; Guillermo R. Castro ; Giselle Z. Justo ;
Ljubica Tasic
Violacein is a natural purple pigment that shows a wide range of bioactivity. The current review addresses different aspects of violacein, such as its production, purification, and biological activities, aiming to enhance its viability for technological applications.
https://dx.doi.org/10.21577/0103-5053.20250096
Full Paper J. Braz. Chem. Soc. 2025, 36(10), e-20250088, 1-14
Monitoring N-Nitrosamines in Cosmetic Thermal Waters: Analytical Method Development, Validation, and Market Analysis in Brazil
Maria Fernanda A. V. Matos; Gabriela F. P. de Souza; Anna Paula R. de Queiroga; Airton G. Salles Jr.; Susanne Rath
N-Nitrosamines in cosmetic thermal waters: market analysis and analytical method.
https://dx.doi.org/10.21577/0103-5053.20250088
J. Braz. Chem. Soc. 2025, 36(10), e-20250089, 1-9
Polycyclic Aromatic Hydrocarbon Contamination of Personal Protective Equipment of Brazilian Firefighters During Training Exercise
Aline M. Arouca ; Victor Emmanuel D. Aleixo ; Maurício L. Vieira ; Márcio Talhavini ; Ingrid T. Weber
Quantification of polycyclic aromatic hydrocarbons (PAHs) deposited on the personal protective equipment (PPE) of firefighters, during firefighting training.
https://dx.doi.org/10.21577/0103-5053.20250089
J. Braz. Chem. Soc. 2025, 36(10), e-20250091, 1-11
Technological Reconstruction and Chemical Similarities of Fine Earthenware from the 18th and 19th Centuries Using EDXRF (State of Piauí, Brazil)
Neiva Maria N. Oliveira; Benedito B. Farias Filho ; Christian Dário S. de Melo; Wilkins O. de Barros
This study investigates the technological reconstruction and chemical composition of fine earthenware from the 18th and 19th centuries in Piauí.
https://dx.doi.org/10.21577/0103-5053.20250091
J. Braz. Chem. Soc. 2025, 36(10), e-20250092, 1-11
Synthesis and Characterization of Graphene Applied to Energy Storage: A Statistical and Electrochemical Study of the Effect of High-Energy Milling on the Efficiency of the Material
Emilly C. Silva; Aluísio C. Pinto; Charlie G. Gomes; Raimundo R. Passos; Consuelo A. da Frota; Leandro A. Pocrifka
This figure represents the physical grinding modifications performed on graphite, using parameters obtained through multivariate analysis, resulting in capacitive graphene and electrochemical tests.
https://dx.doi.org/10.21577/0103-5053.20250092
J. Braz. Chem. Soc. 2025, 36(10), e-20250093, 1-10
High Selective N-Acylhydrazones Silver(I) Complexes against Tuberculosis
Paulo Victor P. dos Santos; Nícolas Glanzmann; Adilson D. da Silva; Fernando R. Pavan; Christian S. C. Canales; Cesar A. Roque‑Borda; Pedro P. Corbi; Douglas H. Pereira; Kaíque A. D'Oliveira; Alexandre Cuin
Biological results of N-acylhydrazones from isoniazid and aldehydes showed silver(I) complexes with N-acylhydrazones as promising antitubercular drugs with high selectivity index.
https://dx.doi.org/10.21577/0103-5053.20250093
J. Braz. Chem. Soc. 2025, 36(10), e-20250095, 1-8
Unveiling the Absolute Configuration of Diarylheptanoid Hirsutanonol: Going Beyond Optical Rotations
Arthur R. de Souza; Julia C. F. Ximenes; Caio V. N. Borges; Samir F. A. Cavalcante; Marcio Fronza; Thiago Barth; Shaft C. Pinto ; Fernando M. Santos Jr.
In this paper, the absolute configuration of (+)-hirsutanonol was unambiguously determined by means of optical rotation (OR) and electronic circular dichroism (ECD) chiroptical properties supported by quantum chemical calculations.
https://dx.doi.org/10.21577/0103-5053.20250095
J. Braz. Chem. Soc. 2025, 36(10), e-20250097, 1-12
Optimization of Biochar Synthesis from Cosmetic Industry Sludge for Enhanced Removal of Enrofloxacin
Antonio Machado Netto ; José Pedro R. Ferreira ; Keivison A. Monteiro ; Caio S. de Lima ; Jodieh O. S. Varejão ;
Eduardo Vinicius V. Varejão ; Natália S. Renato ; Renata P. L. Moreira
Biochar production from industrial sludge and cosmetic waste promotes the circular economy while removing contaminants from aqueous effluents.
https://dx.doi.org/10.21577/0103-5053.20250097
J. Braz. Chem. Soc. 2025, 36(10), e-20250099, 1-15
Developing a Superkeggin-Type Polyoxovanadate to Assemble Homogeneous Films Based on Poly(vinyl chloride): A Combined Experimental and Theoretical Study
Bianca R. Brito ; Lucas G. Fachini ; Kahoana Postal ; Rúbia Camila R. Bottini ; Eduardo L. de Sá ; Sônia F. Zawadzki ; Giovana G. Nunes
A mixed valence polyoxovanadate and poly(vinyl chloride) forms green homogeneous films, studied by molecular docking.
https://dx.doi.org/10.21577/0103-5053.20250099
J. Braz. Chem. Soc. 2025, 36(10), e-20250100, 1-8
Ab Initio Study of Hydrogen Adsorption in COF-10
Yingguo Zhao
The calculated adsorption results with two vibrational modes treated as two-dimensional translation reproduce experimental data better.
https://dx.doi.org/10.21577/0103-5053.20250100
J. Braz. Chem. Soc. 2025, 36(10), e-20250101, 1-14
Raman Analysis of Natural Pigments During the Ripening Process in Different Types of Peppers
Mariana T. C. Campos ; Lenize F. Maia ; Howell G. M. Edwards ; Luiz F. Cappa de Oliveira
The figure shows the Raman spectra of different stages of pepper ripening and the marker bands of natural pigments, in addition to the chemical structures of compounds present in them.
https://dx.doi.org/10.21577/0103-5053.20250101
J. Braz. Chem. Soc. 2025, 36(10), e-20250102, 1-16
The Role of Intermolecular Interactions between Donepezil and Methacrylic Acid in the Synthesis of Crosslinked Polymer Microgels for Drug Delivery
Tereza G. F. Gomides; Victor C. Marques; Priscila P. Silva; Gabriela R. R. Fernandes ; Nathany F. Jammal; Flávia S. Marques ;
Ana P. M. Barboza ; Paula M. A. Vieira ; Jacqueline de Souza ; José D. de Souza Filho ; André L. M. Ruela
Polymeric nanoparticles were synthesized to allow the adsorption of donepezil, resulting in the modified release of this drug following its swelling, through a mechanism related to anomalous diffusion from the polymeric matrix.
https://dx.doi.org/10.21577/0103-5053.20250102
J. Braz. Chem. Soc. 2025, 36(10), e-20250103, 1-15
In vivo and in silico Evaluation of Cashew Nut Shell Liquid and Ag-CNSL Nanoparticles for Anxiolytic Activity in Zebrafish via GABAergic Pathways
Thayllan T. Bezerra ; Mayara O. Almeida ; Pergentino N. Maia Júnior ; Emerson Y. A. Sousa ; Maria K. A. Ferreira ;
Antonio W. Silva ; Giuseppe Mele ; Emmanuel S. Marinho ; Hélcio S. Santos ; Jane E. S. A. Menezes ; Diego Lomonaco ; Selma E. Mazzetto
Exploring the biological activities of Ag-cashew nut shell liquid (CNSL) based nanoparticles and the anxiolytic effects in adult zebrafish via participation of GABAergic system.
https://dx.doi.org/10.21577/0103-5053.20250103
J. Braz. Chem. Soc. 2025, 36(10), e-20250104, 1-13
Chemical Variability and Antioxidant Activity of Stingless Bee Melipona seminigra Geopropolis from Different Amazon Regions
Leonard R. S. de Souza ; Sergio M. Nunomura ; Gislene A. C. Zilse ; Marcos B. Machado ; Rita de Cássia S. Nunomura
Nuclear magnetic resonance (NMR), mass spectrometry (MS) and chemometric analyses have shown the link between chemical diversity and the geographic origin in Melipona seminigra geopropolis.
https://dx.doi.org/10.21577/0103-5053.20250104
J. Braz. Chem. Soc. 2025, 36(10), e-20250105, 1-7
Use of Paper Spray Mass Spectrometry to Detect Phytochelatins in Golden Flaxseed Roots after Contact with Arsenate and Selenite
Giselle V. Sousa ; Vânia L. G. Teles ; Luzia V. Modolo ; Rodinei Augusti ; Letícia M. Costa
Paper-spray mass spectrometry for rapid detection of phytochelatins in golden flaxseed roots exposure to arsenate and selenite.
https://dx.doi.org/10.21577/0103-5053.20250105
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
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University of Campinas - UNICAMP
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