JBCS

The structure and activity of metaloporphyrins are modulated by axial and equatorial ligands (highlighted as red circles), by solvents (top left corner), by the microenvironments provided by apoproteins (right bottom corner) and by the association to surfactant- and lipid -containing nanostructures such as micelles and liposomes

The new congeners hydrophilic MAGs and the corresponding synthetic precursors were prepared in high yields (67-90%, one or two steps) under microwave irradiation using glycerol derivatives as starting materials. These are a new potential antiparasitic compounds

The alkaline hydrolysis of bis(4-cyanopyridinium) salts with two pyridinium rings covalently linked by methylene spacers produce compounds constituted by 4-pyridone and 4-carboxamidopyridinium rings. However, the reactant with three methylene groups additionally generates a new product promoted by charge-conformational effects

Microwave-induced combustion was applied for cigarette tobacco samples digestion and further determination of bromine and chlorine by inductively coupled plasma optical emission spectrometry (ICP OES). In addition, it was possible to obtain a single solution suitable for both analytes determination using different analytical techniques and with residual carbon content lower than 1%

Microextraction by packed sorbent (MEPS) is the miniaturization of conventional solid phase extraction (SPE) packed bed devices from milliliter bed volumes to microliter volumes. MEPS can be connected online liquid chromatography (LC) without any modifications. In MEPS the sorbent, 1-2 mg, is either inserted into the syringe (100-250 μL) barrel as a plug or between the needle and the barrel as a cartridge

A stripping method for the determination of the antiretroviral drug efavirenz at submicromolar concentration levels in diluted alkaline electrolyte is described. The utility of the method is demonstrated by the determination of efavirenz in a synthetic mixture containing both lamivudine and zidovudine

The non-thermal plasma experimental setup. The increasing need for clean water has motivated the development of new technologies for water cleaning. Non-thermal plasma can be efficiently applied to a large variety of environmental and industrial processes, in both the aqueous and gaseous phase, and it can be considered as a green technology, that is, less harmful to ecosystems than conventional technologies

In this article, a cheap, simple and reliable method is reported for enrichment and determination of ketoconazole and clotrimazole antifungal residues in cow's milk. Extraction was accomplished using solid phase extraction and samples were subsequently analyzed by HPLC-UV method

The proposed electrolytic system led to the removal of the Pb²⁺ ions from dilute solutions by simultaneous reduction and oxidation in the cathodes and anode. Consequently, significant improvements of the current efficiency and Pb²⁺ fractional conversion (XPb²⁺) or decay of the normalized Pb²⁺ concentration (C/C0) were attained in a short time

This research demonstrated that solar irradiation affected Cu speciation and Cu-DOM interactions in water samples from eutrophic and metal contaminated reservoir. It is a contribution to the understanding of the ecological implications of photooxidation in natural environments, such as the increase of Cu bioavailability

A procedure based on dispersive solid-phase extraction was proposed to determine of pesticides in tomato samples. The method is a multi-class, quick, cheap and can be easily implemented for routine analysis. Different options in the protocol are possible depending on alternate analytical instrumentation available

It was found that the best composition of the Ti/(RuO₂)_(x)Pt_(1-x) electrodes prepared by the polymeric precursor method toward CO and ethanol electrooxidation processes is (x = 0.5). The onset for ethanol oxidation process is 220mV less positive than on Ti/Pt electrodes. The image shows the ethanol electrooxidation mechanism on Ti/(RuO₂)_(x)Pt_(1-x) electrodes prepared by the polymeric precursor method

Fragment- and descriptor-based QSAR models were employed to investigate the potency of a series of deazaguanine analogs as inhibitors of S. mansoni purine nucleoside phosphorylase. The HQSAR contribution maps highlight the contribution of the main fragments to potency (positive in green; detrimental in red)

This work demonstrates that the combination of solid paraffin as binder agent and silica organofunctionalized with 2-aminothiazole groups as chemical modifier was a very efficient strategy to prepare highly stable carbon paste electrodes. These electrodes allowed in a reliable and simultaneous manner the low level quantification of Pb²⁺ and Cu²⁺ in water samples in a very fast way

A significant improvement of the chemical yields (up to 88%), stereoselectivity (> 99:1) and enantiomeric excesses (up to 98%) of (L)-proline catalyzed direct asymmetric aldol reaction was found when proline based chiral ionic liquids (CILs) were ued as additives

Synthesis of a range of hybrid molecules of potential pharmacological interest was accomplished via the reaction of 2-chloroquinoline-3-carbaldehyde with substituted hydrazides in a green and recyclable solvent PEG 400

The synthesis of new ligands and organonickel pincer complexes has been described and their molecular structures were determined by single-crystal X-ray diffraction analysis. The nickel complex [NiBr{1,3-bis(indazolylmethyl)phenyl-N,C,N}] was tested as a catalyst in ethylene polymerization reaction under mild conditions

When a semiconductor as TiO₂ is irradiated by ultraviolet rays, electron/hole (e^-/h⁺) pairs are formed in semiconductor surface and these reactions generate hydroxyl radicals. Hence, the highly oxidants species (OH^o) are able to degrade organic compounds, such as phenols

The figure presents a structural proposal for the association complex formed between the BPP7a heptapeptide and β-cyclodextrin. The peptide and the BPP7a/β-cyclodextrin complex were characterized by circular dichroism, isothermal titration calorimetry and nuclear magnetic resonance spectroscopy

New chloroquine based hybrids were designed in silico incorporating different small N-heterocycles on the side chain amino group, and finally synthesized in excellent yield by a straight forward synthetic methodology

A multielemental method based on the simultaneous determination of Ca, Cd, Co, Cr, Cu, Fe, Mg, Mo, Ni and Zn (non-hydride forming elements), and As, Bi, Sb, Se and Te (hydride forming elements) using a dual nebulizer and online hydride generation by axial view ICP OES has been developed and applied to the analysis of different reference materials

Soil samples DRUV-VIS 2^nd derivative K-M function. The name of hematite, α-Fe₂O₃, is related to the red color observed due to the strong d-d transition around 550 nm

The ring contraction of readily available 1,2-dihydronaphthalenes promoted by iodine(III) gives functionalized indanes under mild conditions

This scheme summarises the two methods used to prepare the fluorescent films based on dansyl derivatives and shows the images of these films when exposed to ultraviolet light

Dispersive liquid-liquid micro extraction of cadmium was developed by dithizone. The organic solvents in sedimented phase made highbackground signals in flame atomic absorption spectrometry. To remove the background signals, we added 0.2 mL 0.5 mol L^-1 nitric acid (strong oxidizing agent) into sedimented phase and then heated at 90 ^oC for 3 min until the organic solvents were evaporated completely