JBCS

21:35, Mon Mar 27

Open Access/APCs

vol. 24, No. 1, 2013, p. 1-176

 

Honoring Our Heritage and Moving Ahead

The planning for the launching of the Journal of the Brazilian Chemical Society (JBCS) started in 1987 and it became a reality in 1990 with three issues per year. Continuous growing led to four issues per year in 1995, six issues per year from 1996 to 2005, eight issues per year from 2006 to 2008, then ten issues per year in 2009 and finally twelve issues per year starting in 2010.
This evolution reflected the increasing number of chemical researchers in our community, producing good science, and the expansion of the graduate programs in chemistry and related areas, leading to an enhancement in the number of submitted manuscripts. In parallel, a consistent growing of international submissions occurred. The qualitative growing is also demonstrated by the JBCS impact factor reaching 1.00 in 2006 and 1.43 in 2011, even though the number of published manuscript had increased.

(Read more at Editorial)


Cover Article
J. Braz. Chem. Soc. 2013, 24(1), 145-163

Potent Antileukemic Action of Naphthoquinoidal Compounds: Evidence for an Intrinsic Death Mechanism based on Oxidative Stress and Inhibition of DNA Repair

Bruno C. Cavalcanti; Igor O. Cabral; Felipe A. R. Rodrigues; Francisco W. A. Barros; Danilo D. Rocha; Hemerson I. F. Magalhães; Dinara J. Moura; Jenifer Saffi; João A. P. Henriques; Tatiane S. C. Carvalho; Manoel O. Moraes; Cláudia Pessoa; Isadora M. M. de Melo; Eufrânio N. da Silva Júnior

How to cite this article

Naphthoquinones are considered privileged structures due to their biological activities and structural properties. Among these substances, lapachones derivatives could be named magic quinones due to their potent antitumor activity. Our work describes this magic, showing the cytotoxic effects against human leukemia cell lines and the complex mechanism of action involving ROS generation and inhibition of DNA repair. Details are discussed in the Article Potent Antileukemic Action of Naphthoquinoidal Compounds: Evidence for an Intrinsic Death Mechanism based on Oxidative Stress and Inhibition of DNA Repair by Bruno C. Cavalcanti, Igor O. Cabral, Felipe A. R. Rodrigues, Francisco W. A. Barros, Danilo D. Rocha, Hemerson I. F. Magalhães, Dinara J. Moura, Jenifer Saffi, João A. P. Henriques, Tatiane S. C. Carvalho, Manoel O. Moraes, Cláudia Pessoa, Isadora M. M. de Melo and Eufrânio N. da Silva Júnior on page 145.

http://dx.doi.org/10.1590/S0103-50532013000100019

Published online: February 19, 2013

Editorial J. Braz. Chem. Soc. 2013, 24(1), 1-4

Honoring Our Heritage and Moving Ahead

Joaquim A. Nóbrega; Vanessa Hatje

How to cite this article

 

http://dx.doi.org/10.1590/S0103-50532013000100001


Articles J. Braz. Chem. Soc. 2013, 24(1), 5-11

A Microflow Analyzer with an Integrated Gas Diffusion Unit

Alexandre Fonseca; Janaína da C. B. Silva

How to cite this article

 

Gas diffusion unit (GDU) in the proposed microflow analyzer and a fiagram for the determination of ammonium.

http://dx.doi.org/10.1590/S0103-50532013000100002

Published online: January 2, 2013

J. Braz. Chem. Soc. 2013, 24(1), 12-16

A New Approach for the Synthesis of 3-Substituted Cytotoxic Nor-β-Lapachones

Mariana F. C. Cardoso; Illana M. C. B. da Silva; Helvécio M. dos Santos Júnior; David R. Rocha; Ana Jérsia Araújo; Claudia Pessoa; Manoel O. de Moraes; Letícia V. C. Lotufo; Fernando de C. da Silva; Wilson C. Santos; Vitor F. Ferreira

How to cite this article

 

The present study details new synthetic methodology for the synthesis of cytotoxic nor-β-lapachone derivatives substituted at C-3 with pyrazole or carbohydrate moieties.

http://dx.doi.org/10.1590/S0103-50532013000100003

Published online: May 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 17-25

Synthesis of Bio-Additives: Transesterification of Ethyl Acetate with Glycerol using Homogeneous or Heterogeneous Acid Catalysts

Bruno A. Meireles; Vera Lúcia P. Pereira

How to cite this article

 

An efficient production of acetins from glycerol via a transesterification process using homogeneous or heterogeneous acid catalysis was performed.

http://dx.doi.org/10.1590/S0103-50532013000100004

Published online: July 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 26-31

Photochemical Degradation of Pyrazosulfuron-Ethyl in Aqueous Solution

Yanhui Wang; Liangwei Du; Lianyang Bai

How to cite this article

 

This work describes the photolysis of pyrazosulfuron-ethyl in aqueous solution. Three tentative pathways are proposed according to the experimental results: cleavage of the sulfonylurea bridge, an intramolecular SNAr reaction and photodesulfonylation which proceeds by a homolitic nitrogen-sulfur cleavage.

http://dx.doi.org/10.1590/S0103-50532013000100005

Published online: July 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 32-39

Electrocatalytic Determination of Cysteamine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of 3,4-Dihydroxycinnamic Acid as a Homogeneous Mediator

Mohsen Keyvanfard; Samad Sami; Hassan Karimi-Maleh; Khadijeh Alizad

How to cite this article

 

A carbon paste electrode chemically modified with multiwall carbon nanotubes in the presence of 3,4-dihydroxycinnamic acid was introduced as a homogeneous mediator for voltammetric determination of cysteamine in aqueous solution.

http://dx.doi.org/10.1590/S0103-50532013000100006

Published online: July 2, 2013

J. Braz. Chem. Soc. 2013, 24(1), 40-50

Characterization of ZSM-5 Modified with Niobium Pentoxide: the Study of Thiophene Adsorption

Rodrigo M. Cavalcanti; Ivoneide de C. L. Barros; José A. Dias; Sílvia C. L. Dias

How to cite this article

 

The focus of this work is the investigation of adsorption of the thiophene by Nb2O5 impregnated in ZSM-5 by means of kinetic and thermodynamic study of adsorption. The figure is for simple illustration of the process of adsorption.

http://dx.doi.org/10.1590/S0103-50532013000100007

Published online: July 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 51-57

Evaluation Study of an Ion Selective Field Effect Transistor Electrode for Measuring Quality Parameters of Fuel Ethanol

Fabiano B. Gonzaga; Sidney P. Sobral; Carla M. Ribeiro; Mary A. Gonçalves

How to cite this article

 

This work presents an evaluation study of an ion selective field effect transistor (ISFET) electrode, compared to two glass electrodes containing different reference filling solutions, for measuring pH and acid number of several hydrous and anhydrous
fuel ethanol samples.

http://dx.doi.org/10.1590/S0103-50532013000100008

Published online: July 2, 2013

J. Braz. Chem. Soc. 2013, 24(1), 58-67

Assessment of Metal Concentration in the Billings Reservoir Sediments, São Paulo State, Southeastern Brazil

Marcos A. Hortellani; Jorge E. S. Sarkis; Luciana C. B. Menezes; Renata Bazante-Yamaguishi; Alder S. A. Pereira; Priscila F. G. Garcia; Lídia S. Maruyama; Paula M. Gênova de Castro

How to cite this article

 

The levels of Hg, Pb, Cd, Ni, Co, Cu, Mn, Fe, Al and Zn in sediments from 13 fishing points of the Billings Reservoir were assessed. Only Fe and Co seemed natural occurrence, the other metals are possibly associated with anthropogenic sources. Figure shows (MPI) for all elements and (IGeo) to Hg and Cu with indicative of sediments moderately to highly polluted.

http://dx.doi.org/10.1590/S0103-50532013000100009

Published online: July 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 68-75

Partial Oxidation of Methane to Syngas on Rh/Al2O3 and Rh/Ce-ZrO2 Catalysts

Raquel L. Oliveira; Isabela G. Bitencourt; Fabio B. Passos

How to cite this article

 

With Rh/CeZrO2 catalysts, DRIFTS (diffuse reflectance infrared spectroscopy) experiments of adsorbed CO showed the formation of different rhodium species on various supports. The effect of the metal dispersion, oxygen storage capacity and activity of these catalysts for the partial oxidation of methane were discussed.

http://dx.doi.org/10.1590/S0103-50532013000100010

Published online: July 2, 2013

J. Braz. Chem. Soc. 2013, 24(1), 76-84

Degradation of the Herbicide Paraquat by Photo-Fenton Process: Optimization by Experimental Design and Toxicity Assessment

Alam G. Trovó; Oswaldo Gomes Junior; Antonio E. H. Machado; Waldomiro Borges Neto; Jader O. Silva

How to cite this article

 

Experimental design and response surface methodology were employed to evaluate the role (synergistic or antagonistic effects) of Fenton's reagents and to choose the better conditions that result in a higher efficiency of paraquat mineralization during
photo-Fenton process.

http://dx.doi.org/10.1590/S0103-50532013000100011

Published online: July 2, 2013

J. Braz. Chem. Soc. 2013, 24(1), 85-91

HPLC/DAD Determination of Rosmarinic Acid in Salvia officinalis: Sample Preparation Optimization by Factorial Design

Karina B. de Oliveira; Brás H. de Oliveira

How to cite this article

 

Rosmarinic acid is a potent antioxidant found in sage and in other plant species. Results from HPLC analysis may be affected by auto-oxidation during solvent extraction of plant material. Factorial designs of experiments were used for optimization of the sample preparation. The use of antioxidants in the extraction solvent prevented the analyte degradation producing more accurate results.

http://dx.doi.org/10.1590/S0103-50532013000100012

Published online: July 2, 2013


J. Braz. Chem. Soc. 2013, 24(1), 92-99

Modified Eremophilanes and Anti-Inflammatory Activity of Psacalium cirsiifolium

Amira Arciniegas; Ana L. Pérez-Castorena; Antonio Nieto-Camacho; José Luis Villaseñor; Alfonso Romo de Vivar

How to cite this article

 

Four new modified eremophilanes (1-4) were isolated from P. cirsiifolium. 2α-Hydroxyadenostin B (4) showed anti-inflammatory activity (IC50 0.41 μmol per ear) and a neutrophil inhibition effect measured by the myeloperoxidase assay similar to that of indomethacin.

http://dx.doi.org/10.1590/S0103-50532013000100013

Published online: February 15, 2013


J. Braz. Chem. Soc. 2013, 24(1), 100-105

Oxidative Dehydration of Glycerol to Acrylic Acid over Vanadium-Impregnated Zeolite Beta

Carolina F. M. Pestana; Antônio C. O. Guerra; Glaucio B. Ferreira; Cássia C. Turci; Claudio J. A. Mota

How to cite this article

 

The oxidative dehydration of glycerol to acrylic acid was studied over V-impregnated zeolite Beta. Acrylic acid was observed with approximately 20% selectivity at 548 K.

http://dx.doi.org/10.1590/S0103-50532013000100014

Published online: February 15, 2013

J. Braz. Chem. Soc. 2013, 24(1), 106-114

Coprecipitative Preconcentration of Cr(III), Pb(II), Zn(II), Cd(II) and Mn(II) Ions with Al(III) and Fe(III) Carriers and Chromotrope 2B Reagent and their FAAS Determination in Various Water and Food Samples

Berrak Başbuğ; Şerife Tokalıoğlu

How to cite this article

 

Scanning electron microscopy (SEM) images of (a)Al(III)-chromotrope 2B coprecipitant with analytes; Cr(III), Pb(II) and Zn(II) (b) Fe(III)-chromotrope 2B coprecipitant with analytes; Cd(II), Mn(II), Pb(II) and Zn(II) are shown. The surface morphology of the precipitates is changed in the presence of chromotrope 2B reagent as well as analytes for both carriers.

http://dx.doi.org/10.1590/S0103-50532013000100015

Published online: February 18, 2013

J. Braz. Chem. Soc. 2013, 24(1), 115-120

Synthesis and Testing of 3-Acetyl-2,5-Disubstituted-2,3-Dihydro-1,3,4-oxadiazole Derivatives for Antifungal Activity Against Selected Candida Species

Cledualdo S. de Oliveira; Bruno F. Lira; José M. Barbosa-Filho; Jorge G. F. Lorenzo; Camilla P. de Menezes; Jessyca M. C. G. dos Santos; Edeltrudes de O. Lima; Petrônio F. de Athayde-Filho

How to cite this article

 

N-acylhydrazones are particularly versatile for synthesis of compounds containing nitrogen. In this work, they were used as key substrates for the synthesis of 1,3,4-oxadiazolines biologically active.

http://dx.doi.org/10.1590/S0103-50532013000100016

Published online: February 18, 2013


J. Braz. Chem. Soc. 2013, 24(1), 121-132

Preparation and Evaluation of Chitosan Beads Immobilized with Iron(III) for the Removal of As(III) and As(V) from Water

José de O. Marques Neto; Carlos R. Bellato; Jaderson L. Milagres; Kenia D. Pessoa; Elson S. de Alvarenga

How to cite this article

 

The crosslinked chitosan-Fe(III) (Ch-FeCL) adsorbent was developed using Fe(III) immobilized on chitosan beads. After the drying process, the beads have a diameter of about 1 mm and are stable in air. The pH value for removal of As(III) and As(V) was 7.0. The adsorbent was successfully applied for the removal of As(III) and As(V) from natural water samples.

http://dx.doi.org/10.1590/S0103-50532013000100017

Published online: February 18, 2013

J. Braz. Chem. Soc. 2013, 24(1), 133-144

Biological and Structure-Activity Evaluation of Chalcone Derivatives against Bacteria and Fungi

Wender A. Silva; Carlos Kleber Z. Andrade; Hamilton B. Napolitano; Ivo Vencato; Carlito Lariucci; Miriam. R. C. de Castro; Ademir J. Camargo

How to cite this article

 

The antibacterial and antifungal activities of several chalcones were determined by the minimal inhibitory concentration against different microorganisms (Gram-positive and Gram-negative bacteria and fungi). Chemometric studies were carried out in order to identify a potential structure-activity relationship.

http://dx.doi.org/10.1590/S0103-50532013000100018

Published online: February 19, 2013


J. Braz. Chem. Soc. 2013, 24(1), 145-163

Potent Antileukemic Action of Naphthoquinoidal Compounds: Evidence for an Intrinsic Death Mechanism based on Oxidative Stress and Inhibition of DNA Repair

Bruno C. Cavalcanti; Igor O. Cabral; Felipe A. R. Rodrigues; Francisco W. A. Barros; Danilo D. Rocha; Hemerson I. F. Magalhães; Dinara J. Moura; Jenifer Saffi; João A. P. Henriques; Tatiane S. C. Carvalho; Manoel O. Moraes; Cláudia Pessoa; Isadora M. M. de Melo; Eufrânio N. da Silva Júnior

How to cite this article

 

The present study describes that nor-β-lapachone derivatives exhibited pronounced cytotoxic effects against four human leukemia cell lines. Complex studies were conducted to clarify the mechanism of action related to the cytotoxic activity of these derivatives.

http://dx.doi.org/10.1590/S0103-50532013000100019

Published online: February 19, 2013


J. Braz. Chem. Soc. 2013, 24(1), 164-170

Chemical Characterization of Essential Oils from Drimys angustifolia Miers (Winteraceae) and Antibacterial Activity of their Major Compounds

Thalita G. Santos; Jocinei Dognini; Iêda M. Begnini; Ricardo A. Rebelo; Marcio Verdi; André L. de Gasper; Eduardo M. Dalmarco

How to cite this article

 

Drimenol and bicyclogermacrene were isolated from the essential oils of Drimys angustifolia. Antibacterial activity (MIC) of these isolated compounds as well as of their binary mixtures was evaluated. No synergism was observed.

http://dx.doi.org/10.1590/S0103-50532013000100020

Published online: February 20, 2013


Short Report J. Braz. Chem. Soc. 2013, 24(1), 171-176

β-Cyclodextrin Coated Fe3O4 Nanoparticles: a Simple Preparation and Application for Selective Oxidation of Alcohols in Water

Jie Zhu; Peng-cheng Wang; Ming Lu

How to cite this article

 

A magnetically separable β-cyclodextrin (β-CD) was developed and used for oxidation of various alcohols. Water was used as the only solvent and NaOCl as a cheap and green oxidant. Facilitated recovery of β-CD and excellent efficiency for selective oxidation of alcohols were achieved.

http://dx.doi.org/10.1590/S0103-50532013000100021

Published online: February 7, 2013

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
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