5th BCNP and XXXI RESEM: a Tribute to Biodiversity
Special Issue on the 5th Brazilian Conference on Natural Products and XXXI Meeting on Micromolecular Evolution, Systematics and Ecology
David J. NewmanHow to cite this article
The influence of natural products on β-agonists/antagonists, anti-tumor and antiviral agents.
Asmaa Boufridi; Ronald J. QuinnHow to cite this article
Limit metabolome space to drug space. Drug-like properties - Lipinski's rule-of-five. Use standards with known physicochemical properties to calibrate the column. Correlate log P to retention time (tR).
Kirsten R. Benjamin; Iris R. Silva; João P. Cherubim; Derek McPhee; Chris J. PaddonHow to cite this article
Genes encoding the biosynthetic pathway for production of a valuable product (e.g., farnesene) in a native organism are expressed in a heterologous microbial host (e.g., yeast). The engineered yeast produces farnesene by commercial fermentation. Copyright © 2016 Amyris, inc. All rights reserved.
James J. La Clair; William Fenical; Leticia V. Costa-LotufoHow to cite this article
Elucidating the mode of action (MOA) and associated biomolecular targets of a natural product is often one of the bottlenecks in the drug discovery process. We present an overview of recent developments on an immunoaffinity fluorescent (IAF) approach that unites cellular microscopy with immunoaffinity target identification to rapidly characterize and subsequently validate the targets and cellular activity of natural products.
Nivea O. Calixto; Meri Emili F. Pinto; Suelem D. Ramalho; Marcela C. M. Burger; Antonio F. Bobey; Maria Claudia Marx Young; Vanderlan S. Bolzani; Angelo C. PintoHow to cite this article
Highlighting the relevant literature from 1962 until 2015, on taxonomy, chemotaxonomy, traditional uses, pharmacological properties, chemical composition and ecological approach from Psychotria genus.
Felipe C. Wouters; Jonathan Gershenzon; Daniel G. VassãoHow to cite this article
Benzoxazinoids constitute a diverse family of plant secondary metabolites with defensive roles against herbivores, pathogens, and competing plants. Their chemical properties and possible modes of action are discussed in the context of their biological activities.
Flora M. F. Moreira; Julio Croda; Maria H. Sarragiotto; Mary A. Foglio; Ana L. T. G. Ruiz; João E. Carvalho; Anelise S. N. FormagioHow to cite this article
Novel 1-substituted-phenyl-β-carbolines with an amino or guanidinium group-terminated side chain at C-3 were evaluated for in vitro anti-tuberculosis, antiproliferative properties and through in silico study.
Douglas L. Rodenburg; Kamilla Alves; Wilmer H. Perera; Taylor Ramsaroop; Raquel Carvalho; James D. McChesneyHow to cite this article
Large scale purification process for steviol glycosides from a commercial crude extract of Stevia rebaudiana.
João Luiz Baldim; Marisi Gomes SoaresHow to cite this article
Replicons of Burkholderia thailandensis strains related to the production of three natural products (NPs). The biosynthetic gene clusters (BGCs) related to burkholdac were further analyzed and their side chain differentiation were tracked according to their genomes explaining the side chains modifications for this NP.
Denise M. Selegato; Rafael T. Freire; Alberto Tannús; Ian Castro-GamboaHow to cite this article
Workflow of the dereplication method: 1H NMR data from F. oxyporum and F. solani extracts were subjected to principal component analysis (PCA) for the selection of important chemical shifts region (loading values), followed by dereplication algorithm that extracts real 1H NMR peaks from the selected loading regions, enabling, through the comparison with an in-house NMR libraries and online databases, the identification of important bioactive metabolites in complex mixture.
Eduardo A. A. Pinheiro; Fabio C. Borges; Jeferson R. S. Pina; Leila R. S. Ferreira; Jorgeffson S. Cordeiro; Josiwander M. Carvalho; André O. Feitosa; Francinete R. Campos; Andersson Barison; Afonso D. L. Souza; Patrícia S. B. Marinho; Andrey M. R. MarinhoHow to cite this article
This paper describes the isolation of the compounds ergosterol peroxide, monocerin, annularin I and annularin J of the biomass extracts of Exserohilum rostratum. The compounds annularin I and annularin J are new natural products.
Carlos H. Z. Martins; José R. TrigoHow to cite this article
The pericopine moth Scearctia figulina transforms pyrrolizidine alkaloids from their host plant Heliotropium transalpinum.
Taícia Pacheco Fill; Heloisa Fassina Pallini; Luciana da Silva Amaral; José Vinicius da Silva; Danielle Lazarin Bidóia; Francieli Peron; Francielle Pelegrin Garcia; Celso Vataru Nakamura; Edson Rodrigues-FilhoHow to cite this article
Medium composition modification locked verruculogen biosynthesis and addressed proline to the production of the cyclodepsipeptide JBIR 113 by the fungus P. brasilianum.
Natália A. B. Tinoco; Thais M. Uekane; Anna Tsukui; Paula F. de Aguiar; Cláudia M. L. L. Teixeira; Claudia M. RezendeHow to cite this article
Volatiles from Dunaliella bardawil carotenoids produced by microwave irradiation and water bath controlled heating.
Francine S. A. da Fonseca; Marília Medeiros; Adriana T. Salomão; João Vasconcellos-Neto; Anita J. MarsaioliHow to cite this article
Phloea subquadrata (Heteroptera, Phloeidae) and two molecules of (E)-4-oxo-2-hexenal which dimerize in the scent gland.
Célio F. F. Angolini; Ana B. Gonçalves; Renata Sigrist; Bruno S. Paulo; Markiyan Samborskyy; Pedro L. R. Cruz; Adriana F. Vivian; Eduardo M. Schmidt; Marcos N. Eberlin; Welington L. Araújo; Luciana G. de OliveiraHow to cite this article
Mining DNA coupled with networking and analytical tools is a new-fashioned strategy to guide dereplication and finding for new therapeutic targets.
Jimmy Yuk; Dhavalkumar N. Patel; Giorgis Isaac; Kerri Smith; Mark Wrona; Hernando J. Olivos; Kate YuHow to cite this article
Classification of authentic and commercial ginseng using multivariate statistical analysis with ultra-performance liquid chromatography (UPLC)-quadrupole time-of-flight (QTOF)-mass spectrometry.
Kolby J. Jardine; Bruno O. Gimenez; Alessandro C. Araújo; Roberto L. Cunha; Juliana Feitosa Felizzola; Luani R. Piva; Jeffrey Q. Chambers; Niro HiguchiHow to cite this article
Tissue specific volatile organic compounds (VOC) emissions from Oil Palm plantations into the atmosphere during fruit oil processing resulting in emissions of 6-methyl-5-hepten-2-one (MHO) as an oxidation biomarker of lycopene; pollinator attraction resulting in floral emissions of estragole, and leaf photosynthesis resulting in leaf emissions of isoprene. Individual tissue measurements of VOC emissions were made using plant enclosure methods while diurnal concentrations of ambient VOCs were made on a walkup flux tower at the plantation scale near Belém, Brazil.
Kátia R. Prieto; Lívia S. de Medeiros; Marsele M. Isidoro; Leonardo Toffano; Maria Fátima G. F. da Silva; João B. Fernandes; Paulo C. Vieira; Moacir R. Forim; Edson Rodrigues-Filho; Rodrigo M. Stuart; Marcos A. MachadoHow to cite this article
Using LC-ESI-MS/MS analysis, five toxins ACTG-C, D, E and F, and AK-toxin II were identified in A. alternata, ACT-toxins appear to be absent.
Diogo M. Vidal; Carla F. Fávaro; Matheus M. Guimarães; Paulo H. G. ZarbinHow to cite this article
This paper describes the structure elucidation of the male-produced sex pheromone of the soldier beetle Chauliognathus fallax through GC-EAD, GC-MS and GC-FTIR analyses, microderivatization and synthesis. The natural compound was identified as (Z)-tricos-11-ene.
Lívia P. Horta; Yane C. C. Mota; Gisele Maria Barbosa; Taniris C. Braga; Ivanildo E. Marriel; Ângelo de Fátima; Luzia V. ModoloHow to cite this article
Hybrids of plant phenolic natural products protocatechuic aldehyde, syringaldehyde or vanillin with (thio)urea were obtained and investigated for the potential as urease inhibitors of agricultural interest.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
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