Recent Papers - Machine Learning Special Issue
Reviews/Accounts - last 5 years
The Challenge of Including Chemodiversity, and the Potential Economic Use of New Natural Compounds and Processes, in the BIOTA/FAPESP Program
Special Issue BIOprospecTA - BIOTA
Mônica T. Pupo; Cameron R. Currie; Jon Clardy
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The fungus-growing ants multilateral symbiosis between three mutualists and one parasite as the rational guide for the discovery of natural products hits and leads.
David J. Newman
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The microbial biosynthetic genes that produced the toxin in the blister beetle are almost the same as those that produced similar toxins in deep and shallow water sponges. Thus "Mother Nature" reuses useful genes apparently across kingdoms. Read the full story in the review.
Denise M. Selegato; Afif F. Monteiro; Natália C. Vieira; Patrícia Cardoso; Victor D. Pavani; Vanderlan S. Bolzani; Ian Castro-Gamboa
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This review aims to provide an updated summary of the main features of Senna spectabilis, compiling all currently available information on the chemical and pharmacological composition of its parts and associated microorganisms.
Dayana R. Gouvea; Gabriela A. Buqui; Joao Luis C. Lopes; Andrea Diniz; Norberto P. Lopes
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A validated UPLC-MS/MS methodology demonstrated that vicenin-2 and lychnofolic acid compounds were distributed and rapidly eliminated from the rat organism.
Larissa A. H. dos Santos; Etiene E. G. Clavico; Lizbeth L. L. Parra; Roberto G. S. Berlinck; Antonio G. Ferreira; Valerie J. Paul; Renato C. Pereira
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Predation of the bryozoan Amathia verticillata by fishes in field assays showed variable results depending on the region where the bryozoan is found. The results indicate that A. verticillata indole alkaloids play no significant role as chemical defenses.
Quentin Favre-Godal; Stephane Dorsaz; Laurence Marcourt; Valentina Bertini; Emmanuelle Dormia; Emilie Michellod; Francine Voinesco; Mahabir Gupta; Katia Gindro; Dominique Sanglard; Emerson F. Queiroz; Jean-Luc Wolfender
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Characterization of the antifungal triterpenoids isolated from Panamanian plants against Candida species.
Rogério Grando; Vanessa H. Souza; Karin M. Monteiro; Ilza M. O. Sousa; Nubia C. A. Queiroz; Joao E. Carvalho; Humberto M. Spindola; Mary A. Foglio
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Data demonstrates the antinociceptive activity of aqueous P. pubescens fruit extract, with lower potency compared to dichloromethane P. pubescens fruit extract. Nevertheless the resulting data corroborates the species folk use.
Amaro E. T. Silva; Larissa A. Guimaraes; Elthon G. Ferreira; Maria da Conceiçao M. Torres; Alison B. da Silva; Paola C. Branco; Francisca Andréa S. Oliveira; Genivaldo G. Z. Silva; Diego V. Wilke; Edilberto R. Silveira; Otília Deusdenia L. Pessoa; Paula C. Jimenez; Leticia V. Costa-Lotufo
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Chemical studies and genome mining of Actinomadura sp. isolated from sediments collected at the St. Peter and St. Paul Archipelago led to the characterization of three cytotoxic prodiginine derivatives.
Marilia Valli; Wanessa Altei; Ricardo N. dos Santos; Emilio C. de Lucca Jr.; Marco A. Dessoy; Renan M. Pioli; Fernando Cotinguiba; Xavier Cachet; Sylvie Michel; Maysa Furlan; Luiz C. Dias; Adriano D. Andricopulo; Vanderlan S. Bolzani
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Natural product piperlongumine and synthetic analogue designed as inhibitor of breast cancer cell line migration.
Francisco C. L. Pinto; José Gustavo L. Almeida; Edilberto R. Silveira; Arinice M. Costa; Larissa A. Guimaraes; Diego V. Wilke; Letícia V. Costa-Lotufo; Maria da Conceiçao M. Torres; Otília Deusdênia L. Pessoa
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Nine ergostan sterols, including two previously unknown, were isolated from the zoanthids Palythoa caribaeorum and Palythoa variabilis. The structures of all compounds were determined, particularly by 1D and 2D NMR data and HRESIMS.
Thiago R. Morais; Ana Paula R. Coutinho; Fernanda F. Camilo; Tereza S. Martins; Patricia Sartorelli; Mariana H. Massaoka; Carlos R. Figueiredo; Joao Henrique G. Lago
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Microwave assisted extraction and ionic liquid was used to obtain cytotoxic metabolites from Schinus terebinthifolius.
Hugo C. R. de Jesus; Alex H. Jeller; Hosana M. Debonsi; Péricles B. Alves; André L. M. Porto
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Monohydroxylation of rac-camphor yielding hydroxylated diastereoisomers at positions C-3, C-5, C-6 and C-8.
Héctor H. Medrado; Edlene O. dos Santos; Erika M. O. Ribeiro; Jorge M. David; Juceni P. David; José Fernando Araújo; Ademir E. do Vale; Moema C. Bellintani; Hugo N. Brandao; Paloma R. Meira
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Tissue culture of Plecthrantus ornatus on Murashige and Skoog (MS) medium with the addition of auxin and cytokinin promotes an overproduction of rosmarinic and caffeic acids.
Vivian E. Cornelio; Fernando V. Maluf; Joao B. Fernandes; Maria Fátima G. F. da Silva; Glaucius Oliva; Rafael V. C. Guido; Paulo C. Vieira
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Bioactivity-guided TcGAPDH assay leading to isolation of tiliroside from Spiranthera odoratissima extract.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access