Recent Papers - Machine Learning Special Issue
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Metal complexes remain an important resource for the generation of chemical diversity in the search for novel anticancer agents. The ruthenium possesses chemical properties that indicate it may be a strong candidate to form a basis for rational anticancer drugs. In the present study novel DNA-intercalating agents with promising anticancer activities, based on ruthenium(II) with the planar ligand dipyrido[3,2-a:2',3'-c]quinoxaline[2,3-b]quinoxaline) were evaluated for their cytotoxicity against human breast tumor cancer cells. Details are presented in the Article Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor by Joao P. Barolli, Rodrigo S. Corrêa, Fabio S. Miranda, Juliana U. Ribeiro, Carlos Bloch Jr., Javier Ellena, Virtudes Moreno, Márcia R. Cominetti and Alzir A. Batista on page 1879.
Joao P. Barolli; Rodrigo S. Corrêa; Fabio S. Miranda; Juliana U. Ribeiro; Carlos Bloch Jr.; Javier Ellena; Virtudes Moreno; Márcia R. Cominetti; Alzir A. Batista
How to cite this articleMetal complexes remain an important resource for the generation of chemical diversity in the search for novel anticancer agents. The ruthenium possesses chemical properties that indicate it may be a strong candidate to form a basis for rational anticancer drugs. In the present study novel DNA-intercalating agents with promising anticancer activities, based on ruthenium(II) with the planar ligand dipyrido[3,2-a:2',3'-c]quinoxaline[2,3-b]quinoxaline) were evaluated for their cytotoxicity against human breast tumor cancer cells. Details are presented in the Article Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor by Joao P. Barolli, Rodrigo S. Corrêa, Fabio S. Miranda, Juliana U. Ribeiro, Carlos Bloch Jr., Javier Ellena, Virtudes Moreno, Márcia R. Cominetti and Alzir A. Batista on page 1879.
Atefeh Abbasi-Ahd; Nader Shokoufi; Sara Adeleh; Kazem Kargosha
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Photo thermal lens effect of gold nanoparticles (GNPs) capped with methimazole.
Tatiane F. Borgati; Guilherme R. Pereira; Geraldo C. Brandao; Juliana O. Santos; Dayane Aparecida M. Fernandes; Renata C. de Paula; Maria Fernanda A. do Nascimento; Luciana F. Soares; Júlio César D. Lopes; José D. de Souza Filho; Alaíde B. de Oliveira
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Five new lupeol 1,2,3-triazole derivatives were synthesized from lupeol which was isolated from Parahancornia fasciculata and were assayed for antiplasmodial and cytotoxic activity.
Mariéli Karling; Thariane C. Bicas; Vanderlei Aparecido de Lima; Tatiane Luiza C. Oldoni
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Optimizing the extraction of phenolic antioxidants from grape and apple pomaces from Brazil using response surface methodology.
Qinhong Yin; Yanqin Zhu; Yaling Yang
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Magnetic solid phase extraction procedure used for the determination of targeted compounds in biological samples.
Daniel N. do Amaral; Fernando R. de Sá Alves; Eliezer J. Barreiro; Stefan A. Laufer; Lídia M. Lima
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A methodology to obtain 7-nitroquinoxalin-2-amine using o-phenylenediamine as starting material in a five-step procedure in good yields and high purity.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
Joao P. Barolli; Rodrigo S. Corrêa; Fabio S. Miranda; Juliana U. Ribeiro; Carlos Bloch Jr.; Javier Ellena; Virtudes Moreno; Márcia R. Cominetti; Alzir A. Batista
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Ruthenium(II) complexes with the extended planar ligand [dipyrido[3,2-a:2′,3′-c]quinoxaline[2,3-b]quinoxaline)] have been synthesized and shown to be active against breast tumor cells (MDA-MB 231 and MCF-7).
Simone M. Golunski; Thamarys Scapini; Tatiani Andressa Modkovski; Camila T. Marques; Aline F. Camargo; Karina Paula Preczeski; Camila Dalla Rosa; Daiane P. Baldissarelli; Jéssica Mulinari; Bruno Venturin; Gean D. L. P. Vargas; Jaqueline G. Buffon; Altemir José Mossi; Helen Treichel
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Using a power of 30% and a temperature of 55 °C an increase in relative activity of 147.9% in the enzyme from soybean meal was obtained.
Ronaldo B. Orfao Jr.; Fabrício de Carvalho; Paula Homem-de-Mello; Fernando H. Bartoloni
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Addition of CuII or FeIII switches OFF the probe emission, but FeIII also induces the formation of a fluorescent coordinated compound (switch ON).
Francine S. A. da Fonseca; Adriana T. Salomao; Joao Vasconcellos-Neto; Thiago I. B. Lopes; Anita J. Marsaioli
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The volatile compounds differed both within and between Phloeidae species. Some compounds were sex specific, and others were characteristic of different developmental stages.
This article is part of the Special Issue BIOprospecTA-BIOTA.
Leandra A. R. Oliveira; Gerlon A. R. Oliveira; Geralda F. Lemes; Wanderson Romao; Boniek G. Vaz; Sérgio Albuquerque; Cristiana Gonçalez; Luciano M. Liao; Maria Teresa F. Bara
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Two new furanoditerpenes were obtained from Pterodon emarginatus. Methyl 6α-acetoxy-7β-hydroxyvouacapan-17β-oate (previously identified) showed leishmanicidal activity.
Sara R. M. Kollar; Etelvino H. Novotny; Claudia J. do Nascimento; Paulo A. Z. Suarez
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1H NMR (60 and 300 MHz) and FTIR-ATR associated with chemometrics were used to quantify esterification of fatty acids with methanol.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
Mariana F. C. Cardoso; Luana S. M. Forezi; Victor G. S. Cavalcante; Cecília S. R. Juliani; Jackson Antônio L. C. Resende; David R. da Rocha; Fernando C. da Silva; Vitor F. Ferreira
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The synthesis of several xanthenes based on the 1,3-dicarbonyl scaffolds lawsone and coumarin was developed using tandem three-component reactions involving the reagents ortho-hydroxybenzaldehyde, as bifunctional reagent, and an appropriate thiol. These reactions generated two series of para- and ortho-naphthoxanthenes that are structurally related to α- and β-pyranaphthoquinones and one series of coumarin-xanthene derivatives.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
Aline P. de Oliveira; Juliana Naozuka
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Enrichment effects with different iron species on translocation of this element, chemical composition (essential elements, proteins and Fe-proteins) and Fe bioaccessibility.
Chen Zhou; Heng Liu
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Recognition mechanism of the nanofibrous film chemosensor for Zn2+.
Camila M. Oliz; Alexander O. Souza; Camila C. Pereira; Richard M. Oliveira; Aline L. Medina; Mariana A. Vieira; Anderson S. Ribeiro; Adriane M. Nunes
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The new mini PTFE vessel was evaluated as a potential system for the preparation of biological samples and subsequent determination of metals.
Zhanglin Ni; Chuanyi Ren; Junyong Cheng; Fubin Tang
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The sixteen rare earth elements content in twelve types of popular flower herb teas and their infusions consumed in China was evaluated by ICP-MS.
Michelle J. C. Rezende; Daniella L. Vale; Paula F. Aguiar; Carlos A. S. Riehl; Debora A. Azevedo
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The stability of biodiesel:diesel blends were studied in actual Brazilian storage conditions. The degradation was quantified by target compounds in the oxidation process and a full factorial design evaluated the effect of variables.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
Tassya T. S. Matos; Juliana Schultz; Muhammad Y. Khan; Everton F. Zanoelo; Antônio S. Mangrich; Bruno R. Araújo; Sandro Navickiene; Luciane P. C. Romao
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Biochars prepared from exhausted husk (EH) and tannin (TAN) derived from black wattle were used to remove thiacloprid (TCL) and thiamethoxam (TMX) agrotoxics from spiked sample of the Marcela Dam, a natural reservoir in Itabaiana Municipality, Sergipe State, Brazil.
Cibele M. S. de Almeida; Ana Cristina Almeida; Tatiana D. Saint'Pierre; José Marcus Godoy
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Boron isotopic composition was applied as a tool to differentiate among Brazilian red wine origin. The results have demonstrated that is possible to discriminate between wines produced on the Southern region from those produced on Sao Francisco Valley and also between the Brazilian red wines from Chilean, Italian and Portuguese wines.
Susana F. Resende; Rafael L. Gouveia; Bernardo S. Oliveira; Wander L. Vasconcelos; Rodinei Augusti
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Summary of the process used to synthesize the TiO2/SiO2-B2O3 ternary nanocomposites.
Marcos Vinícius A. Queirós; Maslândia N. Bezerra; Judith P. A. Feitosa
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The addition of eggshell to an acrylic copolymer improves the gel strength and the water absorption and also provides a more useful destination for the residue.
Marcos A. S. Brasil; Boaventura F. Reis
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Diagram of the setup for reducing sugar determination in wines.
Adriana P. Vieira; Erika M. Stein; Daniel X. Andreguetti; Gerardo Cebrián‑Torrejón; Antonio Doménech-Carbó; Pio Colepicolo; Ana Maria D. C. Ferreira
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A clean synthesis was developed to prepare selenium nanoparticles using fructose as the reducing agent. The obtained nanoparticles presented high toxicity toward cancer cells, and on the contrary are not toxic against human P4 fibroblasts.
Thais P. Gazzi; Mariane Rotta; Anne D. Villela; Valnês Rodrigues-Junior; Leonardo K. B. Martinelli; Francisco Adilson M. Sales; Eduardo Henrique Silva de Sousa; Maria Martha Campos; Luiz Augusto Basso; Diógenes S. Santos; Pablo Machado
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The pentacyanoferrate(II)-isonicotinoylhydrazones inhibited the reaction catalyzed by Mycobacterium tuberculosis 2-trans-enoyl-ACP(CoA) reductase (MtInhA), showed antitubercular activity against M. tuberculosis H37Rv strain with no apparent toxicity to mammalian cells and presented intracellular activity in a macrophage model of infection.
Carlise Frota; Allan F. C. Rossini; Gleison A. Casagrande; Lucas Pizzuti; Cristiano Raminelli
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Diiodo-functionalized benzo[b]furans were achieved through a simple electrophilic iodocyclization reaction involving alkynylated
2-iodoanisoles and molecular iodine in the presence of sodium bicarbonate.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access