JBCS

2:36, Sun Feb 17

Open Access/APCs

Current Issue vol. 30, No. 3, 2019, p. 425-679

 

Special Issue Brazilian Researchers Abroad.



Editorial J. Braz. Chem. Soc. 2019, 30(3), 425

Brazilian Researchers with Scientifically Established Careers in Institutions Outside Brazil

Paulo Cezar Vieira; Roberto M. Torresi

How to cite this article

 

http://dx.doi.org/10.21577/0103-5053.20190015


Account J. Braz. Chem. Soc. 2019, 30(3), 426-435

Using Polymer Reaction Engineering Principles to Help the Environment: The Case of the Canadian Oil Sands Tailings

João B. P. Soares ; Fernanda L. Motta

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Typical water-based oil sands extraction process in northern Alberta, Canada and macroscopic schematic for settling tests on mature fine tailings (MFT) after treatment with polymer flocculants.

http://dx.doi.org/10.21577/0103-5053.20180197

Published online: October 3, 2018

J. Braz. Chem. Soc. 2019, 30(3), 436-453

Synthesis of Bis-Strychnos Alkaloids (-)-Sungucine, (-)-Isosungucine, and (-)-Strychnogucine B from (-)-Strychnine

Senzhi Zhao; Christiana N. Teijaro; Heng Chen; Gopal Sirasani; Shivaiah Vaddypally; Owen O'Sullivan; Michael J. Zdilla; Graham E. Dobereiner ; Rodrigo B. Andrade

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Concise syntheses of bis-Strychnos alkaloids (-)-sungucine, (-)-isosungucine, and (-)-strychnogucine B have been accomplished from (-)-strychnine. Computational chemistry was employed to rationalize the regiochemical course of key transformations therein.

http://dx.doi.org/10.21577/0103-5053.20180217

Published online: November 6, 2018



Articles J. Braz. Chem. Soc. 2019, 30(3), 454-461

Synthesis of New 1,2,3-Triazolo-naphthalimide/phthalimide Conjugates via 'Click' Reaction: DNA Intercalation and Cytotoxic Studies

Nagula Shankaraiah; Niggula P. Kumar; Ramya Tokala; Bulusu S. Gayatri; Venu Talla; Leonardo S. Santos

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1,2,3-Triazolo-naphthalimide/phthalimide conjugates have been synthesized directly from alkyl/benzyl bromides, sodium azide and alkynes by 1,3-dipolar cycloaddition catalyzed by bis[(tetrabutylammonium)di-µ-iodo-diiododicuprate(I)]. The title compounds were evaluated for their in vitro cytotoxic potential and DNA interaction.

http://dx.doi.org/10.21577/0103-5053.20180111

Published online: June 11, 2018


J. Braz. Chem. Soc. 2019, 30(3), 462-471

Trace Element Analysis, Model-Based Clustering and Flushing to Prevent Drinking Water Contamination in Public Schools

Jake A. Carter; Bradley T. Jones; George L. Donati

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Inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) and model-based clustering were used to identify schools more prone to drinking water contamination by As, Cd, Cr, Cu, Pb, Sb, Se and Tl. A 5-60 min flushing procedure is recommended to minimize potential contamination due to water flow stagnation during the summer break.

http://dx.doi.org/10.21577/0103-5053.20180199

Published online: October 8, 2018


J. Braz. Chem. Soc. 2019, 30(3), 472-478

Identification of Antifungal Compounds from the Root Bark of Cordia anisophylla J.S. Mill.

Quentin Favre-Godal; Sébastien Pinto; Stephane Dorsaz; Adriano Rutz; Laurence Marcourt; Mahabir Gupta; Dominique Sanglard; Emerson F. Queiroz ; Jean-Luc Wolfender

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Antifungal compounds from the root bark of Cordia anisophylla J.S. Mill.

http://dx.doi.org/10.21577/0103-5053.20180221

Published online: November 8, 2018


J. Braz. Chem. Soc. 2019, 30(3), 479-491

Lignin-First Biorefining of Lignocellulose: the Impact of Process Severity on the Uniformity of Lignin Oil Composition

Roberto Rinaldi ; Robert T. Woodward; Paola Ferrini; Hebert J. E. Rivera

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In the lignin-first biorefining by H-transfer reactions, process severity impacts on the uniformity of lignin-products' mixture, as addressed in this report.

http://dx.doi.org/10.21577/0103-5053.20180231

Published online: November 26, 2018


J. Braz. Chem. Soc. 2019, 30(3), 492-498

Quantum Chemical Investigation of the Intramolecular Copigmentation Complex of an Acylated Anthocyanin

Juanjuan He; Xue Li; Gustavo T. M. Silva ; Frank H. Quina; Adelia J. A. Aquino

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An ab initio quantum chemical investigation of the spectroscopic properties of the intramolecular copigmentation complex of an acylated anthocyanin.

http://dx.doi.org/10.21577/0103-5053.20180233

Published online: November 29, 2018

J. Braz. Chem. Soc. 2019, 30(3), 499-508

Heterologous Expression of a Putative ClpC Chaperone Gene Leads to Induction of a Host Metabolite

Jana Braesel ; Alessandra S. Eustáquio

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By attempting to heterologously express a biosynthetic gene cluster identified via a resistance-gene-guided approach, we unexpectedly observed induction of a host metabolite. Transcriptional analysis and literature precedence suggest that induction was caused due to the expression of a putative caseinolytic protease C (ClpC) chaperone gene present in the gene cluster.

http://dx.doi.org/10.21577/0103-5053.20180234

Published online: December 3, 2018

J. Braz. Chem. Soc. 2019, 30(3), 509-521

Water-Soluble Benzazole Dyes Fluorescent by ESIPT: Structural Characterization, Photophysical Properties and Its Application as a Probe for Direct Staining of Helminths

Hélio L. Barros ; Sandra M. T. Marques; Valter Stefani

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Photophysical properties of water-soluble benzazole dyes fluorescent by excited state intramolecular proton transfer mechanism (ESIPT) and their applications in cell imaging.

http://dx.doi.org/10.21577/0103-5053.20180193

Published online: September 28, 2018


J. Braz. Chem. Soc. 2019, 30(3), 522-527

Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.

Maiara S. Borges; Carolina R. Biasetto; Vanessa M. Chapla; Samad N. Ebrahimi; Mayra F. Costa; Vanderlan S. Bolzani; Angela R. Araujo

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A new compound methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate and four known compounds isolated from Saccharicola sp.

http://dx.doi.org/10.21577/0103-5053.20180201

Published online: October 9, 2018


J. Braz. Chem. Soc. 2019, 30(3), 528-540

Studies Toward the Synthesis of Caramboxin Analogues

Ronaldo E. Oliveira Filho ; Vanessa M. Higa ; Álvaro T. Omori

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The Vilsmeier-Haack formylation of aromatic compounds is the key step in the synthesis of caramboxin analogues.

http://dx.doi.org/10.21577/0103-5053.20180202

Published online: October 9, 2018


J. Braz. Chem. Soc. 2019, 30(3), 541-561

Synthesis of Nerol Derivatives Containing a 1,2,3-Triazole Moiety and Evaluation of Their Activities against Cancer Cell Lines

Róbson R. Teixeira ; Adalberto M. da Silva; Raoni P. Siqueira; Victor Hugo S. Gonçalves; Higor S. Pereira; Rafaela S. Ferreira; Adilson V. Costa; Eduardo B. de Melo; Fávero R. Paula; Márcia M. C. Ferreira ; Gustavo C. Bressan

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Twenty two triazolic derivatives were synthesized and had their cytotoxicity evaluated. 3D quantitative structure-activity relationship (QSAR) models were built for a better understanding of the biological activity results.

http://dx.doi.org/10.21577/0103-5053.20180203

Published online: October 10, 2018


J. Braz. Chem. Soc. 2019, 30(3), 562-570

Methyl Esters Production by Heterogeneous Catalyst Mixtures of CaO/Nb2O5 with Simulation of Analysis of Environmental Impacts

Diana C. Cubides-Román; André F. Constantino; Geraldo F. David; Lucas F. Martins; Reginaldo B. dos Santos; Wanderson Romão; Alvaro Cunha Neto; Valdemar Lacerda Jr.

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Biodiesel production catalyzed by a mixture of CaO and Nb2O5, statistical analysis and simplified process simulation to study environmental impacts.

http://dx.doi.org/10.21577/0103-5053.20180204

Published online: October 10, 2018


J. Braz. Chem. Soc. 2019, 30(3), 571-584

Reduction Potential of RuIII-Based Complexes with Potential Antitumor Activity and Thermodynamics of their Hydrolysis Reactions and Interactions with Possible Biological Targets: a Theoretical Investigation

Eufrásia S. Pereira; Marcelo A. Chagas; Willian R. Rocha

How to cite this article

 

Density functional theory (DFT) calculations were performed to investigate competitive process in solution involving the anticancer trans-tetrachloro(dimethylsulfoxide)imidazole ruthenate(III) (NAMI-A) and trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) complexes.

http://dx.doi.org/10.21577/0103-5053.20180206

Published online: October 11, 2018


J. Braz. Chem. Soc. 2019, 30(3), 585-591

New Approach for the Stereoselective Synthesis of (+)-epi-Cytoxazone

Izabel L. Miranda; Suélen K. Sartori; Marisa A. N. Diaz; Gaspar Diaz-Muñoz

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The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of the target molecule's asymmetric centers in the dihydroxylation step.

http://dx.doi.org/10.21577/0103-5053.20180212

Published online: October 25, 2018


J. Braz. Chem. Soc. 2019, 30(3), 592-596

Study on Experimental Leishmanicidal Activity and in silico of Cytochalasin B

André O. Feitosa; Fábio J. N. Ferreira ; Heliton P. C. Brigido; Mirian L. C. Bastos; Josiwander M. Carvalho; Agnaldo S. Carneiro; Maria F. Dolabela; Patrícia S. B. Marinho; Andrey M. R. Marinho

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It was observed the stability of cytochalasin B in the site of the protein trypanothione reductase (TryR) by computational study. TryR is an important target in the study of leishmanicidal activity, since its inactivation can kill or stop the growth of the protozoan.

http://dx.doi.org/10.21577/0103-5053.20180222

Published online: November 9, 2018


J. Braz. Chem. Soc. 2019, 30(3), 597-613

Mixed Ternary Mononuclear Copper(II) Complexes Based on Valproic Acid with 1,10-Phenanthroline and 2,2'-Bipyridine Ligands: DNA Interaction and Cytotoxicity in V79 Cells

Claus T. Pich ; Paulo R. dos Santos; Tatiana V. O. Fortunato; Marilda Chiarello; Iuri M. de Oliveira; Bárbara Q. Soares; Nour E. Ghermani; Miriana Machado; Mariana Roesch-Ely; Françoise Dumas ; Hernan Terenzi; João A. P. Henriques ; Sidnei Moura

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Use of copper(II) complexes based on valproic acid as a genotoxic agents: an approach for the development of a new class of anticancer molecules.

http://dx.doi.org/10.21577/0103-5053.20180229

Published online: November 22, 2018


J. Braz. Chem. Soc. 2019, 30(3), 614-632

Ten Years-Snapshot of the Occurrence of Emerging Contaminants in Drinking, Surface and Ground Waters and Wastewaters from São Paulo State, Brazil

Cassiana C. Montagner ; Fernando F. Sodré ; Raphael D. Acayaba ; Cristiane Vidal ; Iolana Campestrini; Marco A. Locatelli; Igor C. Pescara; Anjaína F. Albuquerque ; Gisela A. Umbuzeiro; Wilson F. Jardim

How to cite this article

 

Occurrence of emerging contaminants in sewage, surface and ground waters and drinking water in the state of São Paulo.

http://dx.doi.org/10.21577/0103-5053.20180232

Published online: November 27, 2018


J. Braz. Chem. Soc. 2019, 30(3), 633-640

Using a Multivariate Approach to Compare Lipid Extraction Protocols from Microalgae Scenedesmus sp.

Daiane F. Dall'Oglio; Laísse C. de Sousa; Samuel A. A. de Sousa; Marco A. S. Garcia; Edymilaís S. Sousa; Sidney G. de Lima; Pelrry S. Costa; Abhishek Guldhe; Faizal Bux; Edmilson M. de Moura; Carla V. R. de Moura

How to cite this article

 

We have proposed a multivariate approach for lipid extraction from microalgae Scenedesmus sp. A reduction in the number of experiments was achieved and proved to be effective.

http://dx.doi.org/10.21577/0103-5053.20180235

Published online: December 3, 2018


J. Braz. Chem. Soc. 2019, 30(3), 641-657

Phosphate Adsorption by Montmorillonites Modified with Lanthanum/Iron and a Laboratory Test using Water from the Jacarepaguá Lagoon (RJ, Brazil)

Laís F. de Castro ; Vitor S. Brandão; Luiz C. Bertolino; Weber F. L. de Souza; Viviane G. Teixeira

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Montmorillonites were modified with La/Fe as potential phosphate adsorbents for eutrophic aquatic environments. Material characterization data were correlated with the study of kinetics and adsorption equilibrium, and applied to a test in the laboratory using water from the Jacarepaguá Lagoon.

http://dx.doi.org/10.21577/0103-5053.20180236

Published online: December 5, 2018


J. Braz. Chem. Soc. 2019, 30(3), 658-672

Relationship between Electrochemical Parameters, Cytotoxicity Data against Cancer Cells of 3-Thio-Substituted Nor-Beta-Lapachone Derivatives. Implications for Cancer Therapy

Yen G. de Paiva; Thaissa L. Silva; André F. A. Xavier; Mariana F. C. Cardoso; Fernando C. da Silva ; Maria F. S. Silva; Daniel P. Pinheiro ; Claudia Pessoa; Vitor F. Ferreira; Marilia O. F. Goulart

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Two distinct and independent redox couples were observed. The compounds have shown relevant cytotoxic activity against four cancer cell lines. The majority of the more electrophilic thionaphthoquinones were active.

http://dx.doi.org/10.21577/0103-5053.20180248

Published online: December 18, 2018


Short Report J. Braz. Chem. Soc. 2019, 30(3), 673-679

Gene Deletion Leads to Improved Valinomycin Production by Streptomyces sp. CBMAI 2042

Bruno S. Paulo; Renata Sigrist; Célio F. F. Angolini ; Marcos N. Eberlin; Luciana G. de Oliveira

How to cite this article

 

A non-ribosomal peptide synthetase (NRPS) gene knockout experiment resulted in 10.5-fold valinomycin overproduction. These results reveal a modification on substrate efflux of competing biosynthetic recruiters.

http://dx.doi.org/10.21577/0103-5053.20180207

Published online: October 15, 2018

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
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