JBCS

Typical water-based oil sands extraction process in northern Alberta, Canada and macroscopic schematic for settling tests on mature fine tailings (MFT) after treatment with polymer flocculants.

Concise syntheses of bis-Strychnos alkaloids (-)-sungucine, (-)-isosungucine, and (-)-strychnogucine B have been accomplished from (-)-strychnine. Computational chemistry was employed to rationalize the regiochemical course of key transformations therein.

1,2,3-Triazolo-naphthalimide/phthalimide conjugates have been synthesized directly from alkyl/benzyl bromides, sodium azide and alkynes by 1,3-dipolar cycloaddition catalyzed by bis[(tetrabutylammonium)di-µ-iodo-diiododicuprate(I)]. The title compounds were evaluated for their in vitro cytotoxic potential and DNA interaction.

Inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) and model-based clustering were used to identify schools more prone to drinking water contamination by As, Cd, Cr, Cu, Pb, Sb, Se and Tl. A 5-60 min flushing procedure is recommended to minimize potential contamination due to water flow stagnation during the summer break.

Antifungal compounds from the root bark of Cordia anisophylla J.S. Mill.

In the lignin-first biorefining by H-transfer reactions, process severity impacts on the uniformity of lignin-products' mixture, as addressed in this report.

An ab initio quantum chemical investigation of the spectroscopic properties of the intramolecular copigmentation complex of an acylated anthocyanin.

By attempting to heterologously express a biosynthetic gene cluster identified via a resistance-gene-guided approach, we unexpectedly observed induction of a host metabolite. Transcriptional analysis and literature precedence suggest that induction was caused due to the expression of a putative caseinolytic protease C (ClpC) chaperone gene present in the gene cluster.

Photophysical properties of water-soluble benzazole dyes fluorescent by excited state intramolecular proton transfer mechanism (ESIPT) and their applications in cell imaging.

A new compound methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate and four known compounds isolated from Saccharicola sp.

The Vilsmeier-Haack formylation of aromatic compounds is the key step in the synthesis of caramboxin analogues.

Twenty two triazolic derivatives were synthesized and had their cytotoxicity evaluated. 3D quantitative structure-activity relationship (QSAR) models were built for a better understanding of the biological activity results.

Biodiesel production catalyzed by a mixture of CaO and Nb₂O₅, statistical analysis and simplified process simulation to study environmental impacts.

Density functional theory (DFT) calculations were performed to investigate competitive process in solution involving the anticancer trans-tetrachloro(dimethylsulfoxide)imidazole ruthenate(III) (NAMI-A) and trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) complexes.

The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of the target molecule's asymmetric centers in the dihydroxylation step.

It was observed the stability of cytochalasin B in the site of the protein trypanothione reductase (TryR) by computational study. TryR is an important target in the study of leishmanicidal activity, since its inactivation can kill or stop the growth of the protozoan.

Use of copper(II) complexes based on valproic acid as a genotoxic agents: an approach for the development of a new class of anticancer molecules.

Occurrence of emerging contaminants in sewage, surface and ground waters and drinking water in the state of Sao Paulo.

We have proposed a multivariate approach for lipid extraction from microalgae Scenedesmus sp. A reduction in the number of experiments was achieved and proved to be effective.

Montmorillonites were modified with La/Fe as potential phosphate adsorbents for eutrophic aquatic environments. Material characterization data were correlated with the study of kinetics and adsorption equilibrium, and applied to a test in the laboratory using water from the Jacarepaguá Lagoon.

Two distinct and independent redox couples were observed. The compounds have shown relevant cytotoxic activity against four cancer cell lines. The majority of the more electrophilic thionaphthoquinones were active.

A non-ribosomal peptide synthetase (NRPS) gene knockout experiment resulted in 10.5-fold valinomycin overproduction. These results reveal a modification on substrate efflux of competing biosynthetic recruiters.