Recent Papers - Machine Learning Special Issue
Reviews/Accounts - last 5 years
This image represents a review article that summarizes the development and application of new compounds in the control of breast cancer. Three distinct chemical classes are highlighted: photosensitizers, caged xanthones, and thiosemicarbazones. The review emphasizes progress in drug development, covering design, structure-activity relationships, and the anti-cancer attributes of each chemical class, which represents potential alternatives to current treatment limitations. Details are presented in the Review Advances in Breast Cancer Drug Discovery: A Review of Therapeutic Strategies and Studies Involving Photosensitizers, Caged Xanthones and Thiosemicarbazones Derivatives by Douglas D. S. Oliveira, Thibault J. W. Jacques Dit Lapierre, Fernanda C. Silva, Ieda V. Cunha, Rafael A. C. Souza, Patrícia A. Matos, Gustavo M. Almeida, Carolina G. Oliveira, Thaise G. Araújo, Tayana M. Tsubone and Celso O. Rezende Jr. on e-20230128.
Douglas D. S. Oliveira; Thibault J. W. Jacques Dit Lapierre ; Fernanda C. Silva; Ieda V. Cunha; Rafael A. C. Souza;
Patrícia A. Matos ; Gustavo M. Almeida; Carolina G. Oliveira
; Thaise G. Araújo; Tayana M. Tsubone
; Celso O. Rezende Jr.
This image represents a review article that summarizes the development and application of new compounds in the control of breast cancer. Three distinct chemical classes are highlighted: photosensitizers, caged xanthones, and thiosemicarbazones. The review emphasizes progress in drug development, covering design, structure-activity relationships, and the anti-cancer attributes of each chemical class, which represents potential alternatives to current treatment limitations. Details are presented in the Review Advances in Breast Cancer Drug Discovery: A Review of Therapeutic Strategies and Studies Involving Photosensitizers, Caged Xanthones and Thiosemicarbazones Derivatives by Douglas D. S. Oliveira, Thibault J. W. Jacques Dit Lapierre, Fernanda C. Silva, Ieda V. Cunha, Rafael A. C. Souza, Patrícia A. Matos, Gustavo M. Almeida, Carolina G. Oliveira, Thaise G. Araújo, Tayana M. Tsubone and Celso O. Rezende Jr. on e-20230128.
Brenno Amaro D. Neto ; Marcos N. Eberlin
Scientific writing from first words to publication, as well as its challenges, including ethical aspects, are presented and discussed in this opinion manuscript.
Douglas D. S. Oliveira; Thibault J. W. Jacques Dit Lapierre ; Fernanda C. Silva; Ieda V. Cunha; Rafael A. C. Souza;
Patrícia A. Matos ; Gustavo M. Almeida; Carolina G. Oliveira
; Thaise G. Araújo; Tayana M. Tsubone
; Celso O. Rezende Jr.
This review presents the principal aspects of the drug discovery process targeting breast cancer and highlights the most promising derivatives of caged xanthones and thiosemicarbazones explored in conventional therapy. Also, it presents details of photodynamic therapy and the action of photosensitizers as an alternative therapy for breast cancer.
Jonatas O. S. Silva ; Honnara S. Granja
; José F. dos Santos
; Lisiane S. Freitas
; Eliana M. Sussuchi
We discuss the use of biochars and hydrochars in electrodes applied in the electrochemical sensing and degradation of target compounds.
Natália N. Kato; Gabriel S. Arini; Ricardo Roberto Silva; Maria Elina Bichuette; José Augusto P. Bitencourt; Norberto P. Lopes
The cave ecosystem hosts a high diversity of microorganisms with complex strategies to survive in limited environmental conditions. Here, we highlight the biology and chemistry of cave microbiomes with multi-omics perspectives.
Rita de Cássia M. Freire; Adalin Cezar M. de Aguiar; Mayra Aparecida Nascimento; Felipe S. O. Cruz; Ann H. Mounteer; Antônio Alberto Silva; Renata P. Lopes
This work presents a compost effluent that has been successfully applied as biofertilizer in lettuce crops.
Ana-Maria Popescu; Jose M. Calderon-Moreno; Kazimir Yanushkevish; Alexei Aplevich; Olga Demidenko
; Elena Ionela Neacsu; Virgil Constantin
A comprehensive study on the corrosion behavior of NdFeB magnets in different electrolytes.
Karen P. S. Lopes; Maria C. C. Lucena; Thiago Inacio B. Lopes; Ámison R. L. da Silva ; Leonardo P. da Silva
; Norberto K. V. Monteiro
; Pedro de Lima-Neto
; Nágila M. P. S. Ricardo
Study of infrared in silico data as a standard database in preliminary method for new synthetic seized drugs.
Ruby S. Gines-Palestino ; Carlos Montalvo-Romero; Guadalupe Luna-Solano; Luis P. Amador-Gómez; Denis Cantú-Lozano
In this research, ZnO and Pt-ZnO were synthesized by a simple method using two different precursors (KOH and NaOH).
Kelly L. Figueira; Roberson D. Girão ; Krislayne N. da Costa; Ana C. R. Barreto; Maria de Nazaré C. Soeiro; Jones Limberger
Synthesis of pyridyl-substituted arylthiazoles with low toxic potential and highly active against Trypanosoma cruzi (half maximal effective concentration (EC50) = 1-2 µM).
Gabriela Bosa; Caroline G. Silva; Bianca R. Brito; Carolina M. Terzi; Fernando Wypych ; Shirley Nakagaki
Some of the synthesis methods already reported for aluminum(III) hydroxide compounds with layered structure of the gibbsite polytype are revisited. The obtained gibbsite material was used as an Al precursor for the synthesis of a lithium/aluminum layered double hydroxide (LDH) and the LDH was used for the immobilization of an anionic porphyrin.
Marinice S. S. Acácio; Eliete C. Alves; Jailson B. de Andrade ; Jeancarlo P. dos Anjos
Carbonyl compounds can be present in beer in free and bound forms. All craft beer samples showed bound-carbonyl compounds, which can negatively influence on the quality of the beverage.
Bruna T. Silva; Antonio J. Demuner ; Daiane E. Blank; Mateus G. Campos; Tiago A. O. Mendes
Levodopa (L-dopa) of Mucuna cinerea was extracted using deep eutectic solvents (DES). Three extracts L-dopa/DES presented control of Parkinson's disease in human glandular kallikrein-1 gene (hGK3) and G protein-coupled receptor kinase-6 gene (GRK6).
Eloize S. Alves; Matheus C. Castro; Bruno H. F. Saqueti; Luciana P. Manin ; Josiane B. Alencar; Joana M. V. Zacarias; Andressa R. S. Bruni; Grasiele S. Madrona; Jeane E. L. Visentainer; Marcelo Cristianini; Oscar O. Santos
; Jesui V. Visentainer
Different processes were evaluated under the lipid and immunological quality of whey human, and the search for the guarantee of nutrients was facilitated. Thus, adapting the processed human whey for use as a complementary product for infant food introduction.
Leonela Godoy Prieto; María T. Lockhart; Marcos J. Lo Fiego
An efficient polymer-supported organotin azide in the synthesis of aryl azides and 5-aryl 1H-tetrazoles.
Fang Fang; Xiaoyan Zhang; Rongrong Bai; Bing Wang ; Mostafa Heidari Majd
Silver nanoparticles synthesized by Moringa peregrina leaves extract increase the expression of genes involved in apoptosis in both intrinsic and extrinsic pathways. It also prevents cancer mutation.
Willian Demos; Lizandra C. B. Micke; Luis H. S. Lacerda ; Bruno S. Souza
; Adriana P. Gerola
; Ricardo F. Affeldt
Fluorescence quenching of mesalazine drug due to interaction with positive-charged pillararene macrocycle at neutral pH.
Basil Minder ; Jacqueline N. Mendonça; Taran Grant
; Norberto P. Lopes
The analysis of gas phase fragmentation reactions in electrospray ionization tandem mass spectrometry (ESI-MS/MS) allowed for the first time to elucidate all ions originating from protonated pumiliotoxin (+)-251D and allopumiliotoxin (+)-267A.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access