12:35, Mon Sep 24

Open Access/APCs

Forthcoming Papers - 2018

Articles published online ahead of print

Articles J. Braz. Chem. Soc. 2018

New Antiproliferative Polyunsaturated Epoxy-Heneicosane Derivatives Isolated from the Brown Alga Lobophora variegata

Fábio N. Ávila; Francisco C. L. Pinto; Pedro B. M. Carneiro; Kayanny Q. Ferreira; Diego V. Wilke; Nádia A. P. Nogueira; Edilberto R. Silveira; Otília Deusdênia L. Pessoa

Two new polyunsaturated 3,4-epoxy-heneicosane derivatives named as epoxy-lobophorene A and B were isolated from the brown alga Lobophora variegata and presented a moderate antiproliferative effect against tumor cell lines.


Published online: September 24, 2018.

J. Braz. Chem. Soc. 2018

Green Chemistry Method Based on PARAFAC EEM Data Modeling for Benzo[a]pyrene Quantitation in Distilled Spirit

Amanda C. Silva; Licarion Pinto; Adriano A. Gomes; Mario C. U. Araujo

Procedure of benzo[a]pyrene (BaP) quantification in cachaças using PARAFAC to overcome the interferences.


Published online: September 24, 2018.

J. Braz. Chem. Soc. 2018

Floral Scent and Nectar Sugar Composition of Temnadenia odorifera (Apocynoideae, Apocynaceae)

Rafael F. Silva; Natália A. B. Tinoco; Anna Tsukui; Cristiana Koschnitzke; Inara C. Silva-Batista; Claudia M. Rezende; Humberto R. Bizzo

Analysis of the chemical composition of the attractants and floral resources available in T. odorifera provided a broader understanding of the mechanisms responsible for plant-insect interactions.


Published online: September 24, 2018.

J. Braz. Chem. Soc. 2018

Evaluation of the Influence of Extraction Conditions on the Isolation and Identification of Volatile Compounds from Cagaita (Eugenia dysenterica) Using HS-SPME/GC-MS

Mauro R. Silva; Gustavo H. Bueno; Raquel L. B. Araújo; Inayara C. A. Lacerda; Lucas G. Freitas; Harriman A. Morais; Rodinei Augusti; Júlio O. F. Melo

Conditions optimization of extraction of volatile compounds from fruit of Eugenia dysenterica using different solid-phase microextraction (SPME) fibers.


Published online: September 21, 2018.

J. Braz. Chem. Soc. 2018

Recombination Study of Dye Sensitized Solar Cells with Natural Extracts

Gideã T. Tractz; Aline Viomar; Bianca V. Dias; Camila A. de Lima; Everson P. Banczek; Maico T. da Cunha; Sandra R. M. Antunes; Paulo R. P. Rodrigues

In this study, frequency domain techniques are used to examine electron transport and dye recombination in natural dye sensitized solar cells.


Published online: September 21, 2018.

J. Braz. Chem. Soc. 2018

Catalytic Cracking of Soybean Oil for Biofuel over γ-Al2O3/CaO Composite Catalyst

Zhi Zheng; Tong Lei; Jun Wang; Yi Wei; Xuejun Liu; Fengwen Yu; Jianbing Ji

Catalytic cracking of soybean oil for biofuel over γ-Al2O3/CaO composite catalysts was conducted in a fixed-bed reactor. The biofuel showed similar chemical composition and fuel properties (low acid value and high calorific value) with the petroleum-based fuel due to the acid-base characters of γ-Al2O3/CaO composite catalysts.


Published online: September 21, 2018.

J. Braz. Chem. Soc. 2018

Fast Triacylglycerol Screening and Semi-Quantitative Analysis of Fatty Acids in Commercial Oils by DIMS with 18-Crown-6 Ether/Trifluoracetic Acid Dopants

Angelica P. P. Tonin; Marcos A. S. Ribeiro; Camila B. Poliseli; Roberta da Silveira; Jesuí V. Visentainer; Valquíria M. Silva; Leomara F. Ribeiro; Rodrigo C. T. de Souza; Cláudio C. de Oliveira; Eduardo C. Meurer

Simple and rapid analysis of commercial oils by direct injection electrospray ionization mass spectrometry (DIMS) and identification of adulteration in olive oil.


Published online: September 20, 2018.

J. Braz. Chem. Soc. 2018

Biodiesel Synthesis: Influence of Alkaline Catalysts in Methanol-Oil Dispersion

José G. Rocha Jr.; Andreza D. M. Mendonça; Daniel A. R. de Campos; Renilson O. Mapele; Cristina M. Barra; Glauco F. Bauerfeldt; Matthieu Tubino

Methyl esters and alkaline catalysts are adsorbed on the surface of the methanol oil, favoring the dispersion of the methanol in the oil phase. The adsorption of potassium is greater than that of sodium.


Published online: September 18, 2018.

J. Braz. Chem. Soc. 2018

Antimicrobial Potential of Natural and Semi-Synthetic ent-Kaurane and ent-Pimarane Diterpenes against Clinically Isolated Gram-Positive Multidrug-Resistant Bacteria

Ana Carolina F. Soares; Priscilla M. Matos; Karime F. da Silva; Carlos H. G. Martins; Rodrigo C. S. Veneziani; Sérgio R. Ambrósio; Herbert J. Dias; Raquel A. dos Santos; Vladimir C. G. Heleno

Two natural diterpenes were evaluated against multi-drug resistant (MDR) Gram-positive bacteria and were converted into 28 semi-synthetic derivatives. Both natural compounds displayed interesting activity overall, but not so good against Staphylococcus aureus, a relevant multi-resistant pathogen. The activities of all derivatives were determined what revealed one with good overall activity and with a noteworthy activity against S. aureus. All other results could further clarify some structure-antimicrobial activity relationship questions about diterpenes.


Published online: September 18, 2018.

J. Braz. Chem. Soc. 2018

Potential Slow Release Fertilizers and Acid Soil Conditioners Obtained by One-Pot Mechanochemical Activation of Chrysotile:Cement Roofing Sheets with K2HPO4

Roger Borges; Fernando Wypych

Chrysotile:cement sheets were milled with K2HPO4 and the amorphous mixture, free of fibers, presents a potential fertilizer and soil conditioner behavior.


Published online: September 17, 2018.

J. Braz. Chem. Soc. 2018

Fast Determination of Iodine Number of Biodiesel Using Capillary Zone Electrophoresis with Multi- and Single-Point Calibration

Alysson V. F. Sako; Gustavo A. Micke

Strategy for fast determination of iodine number of biodiesel samples by capillary zone electrophoresis (CZE). Low sample amount (mg), reactant (µL), and organic solvent (µL) are required.


Published online: September 17, 2018.

J. Braz. Chem. Soc. 2018

Controlled Dehydration of Fe(OH)3 to Fe2O3: Developing Mesopores with Complexing Iron Species for the Adsorption of β-Lactam Antibiotics

Paula S. Pinto; Giovani D. Lanza; José D. Ardisson; Rochel M. Lago

The evolution of the iron hydroxide to produce mesopores containing [FeOx(OH)y] surface sites capable of complexing the amoxicillin molecules.


Published online: September 13, 2018.

J. Braz. Chem. Soc. 2018

Influence of Electrooxidation of Ni Wire Electrodes on the Kinetics of Oxygen Evolution Reaction Studied in 0.1 mol dm-3 NaOH

Andrii Slis; Tomasz Mikolajczyk; Boguslaw Pierozynski

Oxygen evolution reaction (OER) on nickel wire with nickel oxyhydroxide layer.


Published online: September 13, 2018.

J. Braz. Chem. Soc. 2018

Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones

Yesseny A. Vásquez-Martínez; Mauricio E. Osorio; Diego A. San Martín; Marcela A. Carvajal; Alejandra P. Vergara; Elizabeth Sanchez; Marcela Raimondi; Susana A. Zacchino; Carolina Mascayano; Claudia Torrent; Francisco Cabezas; Sophia Mejias; Margarita Montoya; Marcelo Cortez‑San Martín

Nine simple polyoxygenated chalcones were synthesized to evaluate their antimicrobial, anti-inflammatory and antioxidant activities.


Published online: September 13, 2018.

J. Braz. Chem. Soc. 2018

Maximal Information Coefficient and Support Vector Regression Based Nonlinear Feature Selection and QSAR Modeling on Toxicity of Alcohol Compounds to Tadpoles of Rana temporaria

Lifeng Wang; Pengwei Xing; Cong Wang; Xiaomao Zhou; Zhijun Dai; Lianyang Bai

Given a dataset, first, use maximum information coefficient (MIC-filter), support vector regression backward elimination (SVR-BE) and minimal redundancy maximal relevance (mRMR-MIC) to select features. Second, use the multiple linear regression (MLR), partial least square regression (PLS) and support vector regression (SVR) to build quantitative structure activity relationship (QSAR) models.


Published online: September 11, 2018.

J. Braz. Chem. Soc. 2018

2D, 3D and Hybrid QSAR Studies of Nostoclide Analogues as Inhibitors of the Photosystem II

Pedro O. M. de Carvalho; Márcia M. C. Ferreira

2D and 3D molecular descriptors were calculated, selected and used to build quantitative structure-activity relationship (QSAR) models to predict the herbicide activity of a set of nostoclide analogues (experimental data retrieved from the literature). The models were interpreted to understand the ligand-receptor interactions.


Published online: September 11, 2018.

J. Braz. Chem. Soc. 2018

Biomonitoring of Toxic Elements in Plants Collected Near Leather Tanning Industry

Alex R. H. De La Cruz; Lorreine D. S. C. Ferreira; Vinicius P. Andrade; Adriana Gioda

The leather industry has significant economic influence; however, it suffers from the negative impact due to environmental pollution caused by tannery wastes produced during leather processing.


Published online: September 4, 2018.

J. Braz. Chem. Soc. 2018

SPME Fiber Evaluation for Volatile Organic Compounds Extraction from Acerola

Yesenia M. García; José C. M. Rufini; Matheus P. Campos; Mayara N. S. Guedes; Rodinei Augusti; Júlio O. F. Melo

Extraction of volatile organic compounds from acerola fruits through the use of different solid phase microextraction (SPME) fibers.


Published online: September 4, 2018.

J. Braz. Chem. Soc. 2018

Physicochemical Characterizations and Antioxidant Property of Copaiba Oil Loaded into SNEDDS Systems

Denise P. Emerenciano; Bernardo B. D. Baracho; Melyssa L. de Medeiros; Hugo A. O. Rocha; Francisco H. Xavier Jr.; Valdir F. da Veiga Jr.; Maria Aparecida M. Maciel

Copaiba oil-resin loaded into self-nanoemulsion drug delivery systems (SNEDDS) were obtained in order to improve the solubility and bioavailability of this natural oil.


Published online: September 4, 2018.

J. Braz. Chem. Soc. 2018

High Uranium Concentrations in the Groundwater of the Rio de Janeiro State, Brazil, Mountainous Region

José M. Godoy; Paulo R. Ferreira; Elder M. de Souza; Larisse I. da Silva; Isabela C. S. Bittencourt; Felipe Fraifeld

Uranium concentrations higher than the Brazilian regulatory limits were observed in several groundwater wells in the mountainous region near Rio de Janeiro City. Clear water does not mean uncontaminated water.


Published online: September 3, 2018.

J. Braz. Chem. Soc. 2018

Encapsulating TiO2 into Polyvinyl Alcohol Coated Polyacrylonitrile Composite Beads for the Effective Removal of Methylene Blue

Zhenhua Han; Jiali Jin; Yuchao Wang; Zihui Zhang; Junjie Gu; Minrui Ou; Xiaoping Xu

Polyacrylonitrile (PAN)/polyvinyl alcohol (PVA)/TiO2 (PPT) beads structure and removal of methylene blue (MB) under visible light irradiation.


Published online: August 31, 2018.

J. Braz. Chem. Soc. 2018

Use of Coconut Charcoal and Menthone-Thiosemicarbazone Polymer as Solid Phase Materials for the Determination of N,N-Dimethyltryptamine, Harmine, Harmaline, Harmalol, and Tetrahydroharmine in Ayahuasca Beverage by Liquid Chromatography-Tandem Mass Spectrometry

Sandro Navickiene; Luis F. S. Santos; Mônica C. Santos; Alain Gaujac

Evaluation of efficiency of coconut charcoal and menthone-thiosemicarbazone as alternative solid phase extraction adsorbent for the determination of alkaloids in ayahuasca beverage.


Published online: August 30, 2018.

J. Braz. Chem. Soc. 2018

On the Use of an Interpolation Approach for the Choice of Gaussian Polarization Functions

Fernando Ratuchne; Ana C. Mora; Ricardo Celeste; Albérico B. F. da Silva

The polarization exponents (αw) vary with the atomic number (Z) for a sequence of atoms in a row with the same valence structure. Thus, αw can be obtained by interpolation.


Published online: August 30, 2018.

J. Braz. Chem. Soc. 2018

Synthesis, Antimicrobial Activity and Structure-Activity Relationship of Some 5-Arylidene-thiazolidine-2,4-dione Derivatives

Raíssa K. C. de Paiva; Jamerson F. da Silva; Hudieyllen A. Moreira; Osvaldo G. Pinto; Lilian T. F. M. Camargo; Plínio L. F. Naves; Ademir J. Camargo; Luciano Ribeiro; Luciana M. Ramos

The synthesis and antimicrobial activity of thiazolidine-2,4-dione derivatives are described. The structures of the synthesized compounds were confirmed by infrared and nuclear magnetic resonance. All compounds were evaluated for their in vitro antibacterial activity. Density functional theory and principal component analysis were used to discriminate the compounds.


Published online: August 28, 2018.

J. Braz. Chem. Soc. 2018

Male-Specific Volatiles Released by the Big Avocado Seed Weevil Heilipus lauri Boheman (Coleoptera: Curculionidae)

Alicia A. Romero-Frías; Diana C. Sinuco; José Maurício S. Bento

Volatile organic compounds released by Heilipus lauri (Coleoptera: Curculionidae).


Published online: August 28, 2018.

J. Braz. Chem. Soc. 2018

Biotechnological Properties of Sponges from Northeast Brazil: Cliona varians as a Biocatalyst for Enantioselective Reduction of Carbonyl Compounds

Valéria B. Riatto; Mauricio M. Victor; Jaqueline F. Sousa; Carla Menegola

This work describes the first use of marine sponge Cliona varians as biocatalytic agents in the stereoselective reduction of α-keto esters and isatin.


Published online: August 27, 2018.

J. Braz. Chem. Soc. 2018

Sample Preparation Applied to Analysis of Proteins in Cowpea Seeds (Vigna unguiculata (L.) Walp.)

Thábata L. A. B. Nascimento; Tiago L. S. Coelho; Cícero A. Lopes Júnior; Samuel A. A. Sousa; Herbert S. Barbosa

Optimization of sample preparation procedure in the extraction of cowpea proteins using the high-performance liquid chromatography (HPLC) technique as a comparative tool.


Published online: August 22, 2018.

J. Braz. Chem. Soc. 2018

Ultrasonic Extracts of Morinda citrifolia L.: Characterization of Volatile Compounds by Gas Chromatography-Mass Spectrometry

Daiane B. M. Lima; Anaí L. dos Santos; Ariel O. Celestino; Nayna Sampaio; Jéssica Baldez; Maria I. S. Melecchi; Thiago R. Bjerk; Laíza C. Krause; Elina B. Caramão

Sonication extraction from leaves and fruits using response surface methodology and analysis of the extracts by gas chromatography-mass spectrometry (GC-MS) showing as major compounds: octanoic acid, vitamin E, phytol and hydroxymethylfurfural.


Published online: August 22, 2018.

J. Braz. Chem. Soc. 2018

Eco-Friendly Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones Catalyzed by FeCl3/Al2O3 and Analysis of Large 1H NMR Diastereotopic Effect

Isabel Monreal; Mariano Sánchez-Castellanos; Karla Ramírez‑Gualito; Gabriel Cuevas; Karla A. Espinoza; Ignacio A. Rivero

The quinazolinones showed a large range diastereotopic effect that was studied through nuclear magnetic resonance (NMR) and computational calculations.


Published online: August 21, 2018.

J. Braz. Chem. Soc. 2018

Anti-Parasite Activity of Novel 3,5-Diiodophenethyl-benzamides

Manuel Pastrana Restrepo; Verónica Surmay Surmay; Elkin Galeano Jaramillo; Sara Robledo Restrepo

Novel 3,5-diiodophenethyl-benzamides as new lead compounds for the development of new anti-parasites treatment.


Published online: August 20, 2018.

J. Braz. Chem. Soc. 2018

In vitro Evaluation of Ca, Cu, and Mg Bioaccessibility in Fresh and Dried Fruits

Thais T. Mingroni; Juliana Hamada; Alexsandra D. S. Xavier; Cleusa Cavalcante; Angerson N. do Nascimento

An in vitro evaluation of Ca, Cu, and Mg bioaccessibility in fresh and dried fruits was carried out, with results demonstrating that the dehydration process negatively affects bioaccessibility of Ca and Mg in dried fruits.


Published online: August 20, 2018.

J. Braz. Chem. Soc. 2018

Synthesis of 1,2,3-Triazole Derivatives of 4,4'-Dihydroxybenzophenone and Evaluation of Their Elastase Inhibitory Activity

Maria C. F. Dias; Thiago Q. Gularte; Róbson R. Teixeira; Jorge A. N. Santos; Eduardo J. Pilau; Tiago A. O. Mendes; Antônio J. Demuner; Marcelo H. dos Santos

The conversion of 4,4'-dihydroxybenzophenone into a series of 1,2,3-triazolic derivatives resulted in the identification of bis(4-(1-(4-iodobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)benzophenone with significant elastase inhibitory activity (IC50 = 16.6 ± 1.9  M, inhibition constant (Ki) of 11.12  M).


Published online: August 20, 2018.

J. Braz. Chem. Soc. 2018

Influence of Copper and Metallic Alloys on the Oxidation Reaction of Commercial Biodiesel in Mixture with Natural Antioxidant

Letícia T. Chendynski; Érica S. Romagnoli; Ana Carolina G. Mantovani; Marissa Kimura; Leonardo C. Marques; Dionisio Borsato

Influence of copper and metallic alloys on the biodiesel oxidation reaction.


Published online: August 17, 2018.

J. Braz. Chem. Soc. 2018

Synthesis, Photophysical and Electrochemical Properties of Novel D-π-D and D-π-A Triphenylamino-Chalcones and β-Arylchalcones

Rafaela G. M. da Costa; Francisco R. L. Farias; Luis Maqueira; Carlos Castanho Neto; Leonardo S. A. Carneiro; Joseany M. S. Almeida; Camilla D. Buarque; Ricardo Q. Aucélio; Jones Limberger

A series of triphenylamino (TPA)-chalcones and β-arylchalcones, displaying either D-π-D or D-π-A architecture, were synthesized and characterized. Photophysical and electrochemical properties of these compounds were evaluated.


Published online: August 17, 2018.

Communication J. Braz. Chem. Soc. 2018

Old Drawback on Azlactone Formation Revealed by a Combination of Theoretical and Experimental Studies

Pedro P. de Castro; Gabriel M. F. Batista; Danielle L. J. Pinheiro; Hélio F. dos Santos; Giovanni W. Amarante

Novel insights in the formation of different 2-substituted azlactone heterocycles. The formation of 2-aryl and 2-alkyl azlactones are favored by a sum of both kinetic and thermodynamic factors, while the cyclization of 2-alcoxy azlactones is less favored.


Published online: August 16, 2018.

Articles J. Braz. Chem. Soc. 2018

Occurrence of Pesticides and PPCPs in Surface and Drinking Water in Southern Brazil: Data on 4-Year Monitoring

Sergiane S. Caldas; Jean Lucas O. Arias; Caroline Rombaldi; Lucas L. Mello; Maristela B. R. Cerqueira; Ayrton F. Martins; Ednei G. Primel

Fifty-one compounds including PPCPs and pesticides were monitored from 2011 to 2014 in drinking and surface waters in Rio Grande do Sul State.


Published online: August 15, 2018.

Short Report J. Braz. Chem. Soc. 2018

A Facile Synthesis of Novel Isatinspirooxazine Derivatives and Potential in vitro Anti-Proliferative Activity

Iara S. Santos; Fabiana S. Guerra; Lucas F. Bernardino; Patrícia D. Fernandes; Lidilhone Hamerski; Bárbara V. Silva

It was synthesized a new isatinspirooxazine derivative with an half maximal inhibitory concentration (IC50) = 0.34 µM, more potent than the reference drug, doxorubicin (IC50 = 1.88 µM), in breast cancer line MDA-MB231.


Published online: August 15, 2018.

Articles J. Braz. Chem. Soc. 2018

Analysis of Isomeric Cannabinoid Standards and Cannabis Products by UPLC-ESI-TWIM-MS: a Comparison with GC-MS and GC × GC-QMS

Nayara A. dos Santos; Lilian V. Tose; Samantha R. C. da Silva; Michael Murgu; Ricardo M. Kuster; Rafael S. Ortiz; Flavio A. O. Camargo; Boniek G. Vaz; Valdemar Lacerda Jr.; Wanderson Romão

Analysis of cannabinoid standards by ultra performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight-mass spectrometry (UPLC-ESI-QTOF-MS) and UPLC-ESI-travelling wave ion mobility (TWIM)-MS.


Published online: August 14, 2018.

J. Braz. Chem. Soc. 2018

Determination of Parabens in Breast Milk Samples by Dispersive Liquid-Liquid Microextraction (DLLME) and Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry

Caroline F. Grecco; Israel D. Souza; Vinicius R. Acquaro Junior; Maria E. C. Queiroz

Determination of parabens in breast milk samples by dispersive liquid-liquid microextraction (DLLME) and ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS).


Published online: August 10, 2018.

J. Braz. Chem. Soc. 2018

Pyrazolyl-Tetrazoles and Imidazolyl-Pyrazoles as Potential Anticoagulants and their Integrated Multiplex Analysis Virtual Screening

André L. P. G. Lourenço; Percilene F. Vegi; Jéssica V. Faria; Gustavo S. P. Pinto; Maurício S. dos Santos; Plínio C. Sathler; Max S. Saito; Marcos Santana; Tatiana P. P. Dutra; Carlos R. Rodrigues; Robson Q. Monteiro; Alice M. R. Bernardino; Helena C. Castro

Fourteen pyrazole compounds were synthesized and evaluated with regard to anticoagulant and antithrombotic activities. These derivatives were investigated through an integrated multiplex analysis virtual screening (IMA-VS) pipeline.


Published online: August 9, 2018.

J. Braz. Chem. Soc. 2018

Synthesis of Spiro-Pyrrolidinyloxindoles by Oxidative Rearrangement of N-Acyltetrahydro-β-carbolines Using an Oxone/Aqueous Acetone Mixture

Luisa L. Marçal; Simon J. Garden

Substrate face controlled concerted oxidative rearrangement of N-acyltetrahydro-β-carbolines stereoselectively gives spiropyrrolidinyloxindoles.


Published online: August 9, 2018.

Short Report J. Braz. Chem. Soc. 2018

Synthesis, in silico Study and Antimicrobial Evaluation of New Selenoglycolicamides

Helivaldo D. S. Souza; Roxana P. F. de Sousa; Bruno F. Lira; Raquel F. Vilela; Nathalie H. P. B. Borges; José P. de Siqueira‑Junior; Edeltrudes O. Lima; Jeane U. G. Jardim; Gracielle A. T. da Silva; José M. Barbosa‑Filho; Petrônio F. de Athayde‑Filho

The organoselenium compounds presented are prominent in medicinal chemistry; due to the increase of resistant fungi and bacteria, novel organoselenium compounds have been investigated as potent antimicrobials.


Published online: August 6, 2018.

Articles J. Braz. Chem. Soc. 2018

Synthesis and Cytotoxicity Evaluation of a Series of 3-Alkenyl-2-Hydroxy-1,4‑Naphthoquinones Obtained by an Efficient Knoevenagel Condensation

Cibelle C. David; Antonio C. S. Lins; Tania M. S. Silva; Júlia F. Campos; Teresinha G. Silva; Gardenia C. G. Militão; Celso A. Camara

An efficient Knoevenagel condensation between aldehydes and lawsone was performed under new conditions showing good isolated yields in a short reaction time and simple conditions.


Published online: July 31, 2018.

J. Braz. Chem. Soc. 2018

Unprecedented One-Pot Sequence for the Synthesis of Tetrahydroquinoline Alkaloids and Preliminary Evaluation of their Antibacterial Activity

Gaspar Diaz-Muñoz; Izabel L. Miranda; Suélen K. Sartori; Gabriel N. S. Dias; Markus Kohlhoff; Gislaine A. Purgato; Marisa A. N. Diaz

A novel one-pot sequence (in 2 or 3 steps) was developed for the synthesis of the tetrahydroquinoline alkaloids (±)-galipinine, (±)-cuspareine, (±)-galipeine and (±)-angustureine, and the derivative (±)-11-methoxy-5,6,6a,7,8,13-hexahydro-13a-aza-benzo[5,6]cyclohepta[1,2-a]naphthalene-12-ol from their respective Wittig adducts.


Published online: July 30, 2018.

J. Braz. Chem. Soc. 2018

Preparation of Magnetoliposomes with a Green, Low-Cost, Fast and Scalable Methodology and Activity Study against S. aureus and C. freundii Bacterial Strains

Rosangela M. F. da Costa e Silva; Luciano R. S. Lara; Jorge L. López; Ângela L. Andrade; Junnia A. C. Oliveira; Jacqueline A. Takahashi; Henriete S. Vieira; Tulio Matencio; Humberto O. Stumpf; Rosana Z. Domingues

A novel methodology, fast, low-cost and scalable, without the use of organic solvents and with the dual use of soy lecithin to prepare stable magnetoliposomes (MGLs).


Published online: July 30, 2018.

J. Braz. Chem. Soc. 2018

Identification of Fusarium oxysporum Fungus in Wheat Based on Chemical Markers and Qualitative GC-MS Test

Carlos E. R. Senes; Nayara C. Saldan; Willian F. Costa; Terezinha I. E. Svidzinski; Cláudio C. Oliveira

Fusarium oxysporum was cultivated in liquid and solid culture media. Using gas chromatography coupled to mass spectrometry (GC-MS), it was possible to identify secondary metabolites from liquid and solid culture media that can be used as chemical markers for this fungus.


Published online: July 27, 2018.

J. Braz. Chem. Soc. 2018

Evaluation of the Chemical Composition of Dry Feeds for Dogs and Cats

Silvânio S. L. Costa; Ana C. L. Pereira; Elisangela A. Passos; José P. H. Alves; Carlos A. B. Garcia; Rennan G. O. Araujo

In this work, the mineral composition of dry feeds for cat and dog was determined and evaluated according to regulatory agencies.


Published online: July 25, 2018.

J. Braz. Chem. Soc. 2018

Synthesis and Evaluation of Biocide and Cetane Number Improver Additives for Biodiesel from Chemical Changes in Triacylglycerides

Kênia P. Costa; Stella F. do Valle; Thayana F. L. dos Santos; Ellen T. Rangel; Angelo C. Pinto; Paulo A. Z. Suarez; Michelle J. C. Rezende

Biocide candidates from chemical transformations in triacylglycerides were evaluated against microorganisms which have been isolated from biodiesel/diesel blends. Four nitrated derivatives presented fungicidal activity.


Published online: July 20, 2018.

J. Braz. Chem. Soc. 2018

Identification Using Classification Analysis of Flunitrazepam in Necrophagous Larvae via Differential Pulse Voltammetry and Fluorescence Excitation-Emission Matrix (EEM) Spectroscopy

Leomir A. S. de Lima; Camilo L. M. Morais; Jéssica T. Jales; Renata A. Gama; Sherlan G. Lemos; Kássio M. G. Lima

Experimental procedure to obtain samples of fly larvae extract and subsequent analysis by differential pulse voltammetry with E / V vs. Ag/AgCl reference electrode and molecular fluorescence spectroscopy.


Published online: July 18, 2018.

J. Braz. Chem. Soc. 2018

Evaluation of Benzene Derivatives Migration from Solid Residuals by Alternative Leaching Process Using HS‑SPME GC‑MS

Jocinei Dognini; Luiz A. S. Madureira

Alternative leaching process for the determination of benzene derivatives in petrochemical waste using headspace solid-phase micro-extraction gas chromatography-mass spectrometry (HS-SPME GC-MS).


Published online: July 18, 2018.

J. Braz. Chem. Soc. 2018

Radon Levels in a Hospital in Niterói Municipality-RJ, Brazil

Camila R. Silva; Pedro P. Caldeira; Angela S. F. Nani; Emmanoel V. Silva-Filho

The radium present in the soil decays originating 222Rn, a gas with high mobility that diffuses to the surface through pores, fissures in the soil and by the groundwater.


Published online: July 17, 2018.

J. Braz. Chem. Soc. 2018

Anti-Parasite and Cytotoxic Activities of Chloro and Bromo L-Tyrosine Derivatives

Manuel Pastrana Restrepo; Elkin Galeano Jaramillo; Alejandro Martínez Martínez; Ana Mesa Arango; Sara Robledo Restrepo

Bromo and chloro L-tyrosine derivatives actives against L. panamensis.


Published online: July 16, 2018.

J. Braz. Chem. Soc. 2018

Virtual Screening for the Selection of New Candidates to Trypanosoma cruzi Farnesyl Pyrophosphate Synthase Inhibitors

Larissa M. Oliveira; Janay S. C. Araújo; David B. Costa Júnior; Manoelito C. dos Santos Junior; Aníbal F. Santos Júnior; Franco H. A. Leite

Virtual screening to select Trypanosoma cruzi farnesyl pyrophosphate synthase inhibitors.


Published online: July 12, 2018.

Short Report J. Braz. Chem. Soc. 2018

Potential Antileishmanial Activity of 4-N-Acylhydrazone Pyrazolo[3,4-d]pyridazin-7-ones: Synthesis, in vitro Biological Evaluations and Computational Studies

Andrey P. Jacomini; Michael J. V. da Silva; Julia Poletto; Gessica M. Ribeiro; Jessica T. C. Yokoyama; Danielle L. Bidóia; Fávero R. Paula; Celso V. Nakamura; Maria Helena Sarragiotto; Fernanda A. Rosa

Synthesis of new series of pyrazolo[3,4-d]pyridazin-7-ones with antileishmanial activity and low toxicity against Leishmania amazonensis (strain WHOM/BR/75/JOSEFA), promastigote and amastigote forms.


Published online: July 12, 2018.

Articles J. Braz. Chem. Soc. 2018

β-Enaminoesters as Novel Corrosion Inhibitors for Carbon Steel in Acidic Medium

Mariana F. L. P. Carlos; Arthur Valbon; Marcelo A. Neves; Margareth R. L. Santos; Aurea Echevarria

American Iron and Steel Institute (AISI) 1020 carbon steel in 0.5 mol L-1 HCl in absence (blank) and presence of 1 × 10-2 mol L-1 ethyl-(2Z)-3-[(2-phenylethyl)amino]but-2-enoate (EN1).


Published online: July 11, 2018.

J. Braz. Chem. Soc. 2018

Pulp Mill Effluent Treatment Using Plasma Obtained by High Voltage Electrolysis

Alexsandro A. Matias; César Reis; Efraim L. Reis; Cláudio M. Silva; Odilaine I. C. Damasceno; Antônio A. Neves

The plasma is produced between two electrodes immersed in the pulp mill effluent, at 585 V and 200 mA, producing various types of reactive agents, that were used to breakdown diverse organic compounds.


Published online: July 10, 2018.

J. Braz. Chem. Soc. 2018

Metabolite Fingerprinting and Profiling of the Medicinal Grass Eleusine indica Based on HPLC-DAD, UPLC-DAD-MS/MS and NMR Analyses

Evelyn M. C. Peñaloza; Livia M. Casanova; Ivana C. R. Leal; Paula F. de Aguiar; Sônia S. Costa

Crude aqueous extracts of aerial and underground parts of Eleusine indica populations from four different localities were analyzed by high-performance liquid chromatography with diode array detection (HPLC-DAD), ultra-performance liquid chromatography with diode array detector and mass spectrometry (UPLC-DAD-MS/MS) and nuclear magnetic resonance (NMR) spectroscopy.


Published online: July 6, 2018.

J. Braz. Chem. Soc. 2018

Fast Ephedrine Quantification by Gas Chromatography Mass Spectrometry

Gabriel R. A. Carneiro; Andressa M. S. Silva; Raquel M. Cavalcante; Monica C. Padilha; Francisco R. de Aquino Neto; Henrique M. G. Pereira; Vinícius F. Sardela

Straightforward method for ephedrine quantification based on gas chromatography mass spectrometry (GC-MS), without cleanup, and optimized by multivariate Doehlert matrix.


Published online: July 3, 2018.

J. Braz. Chem. Soc. 2018

Facile Synthesis and Characterization of Symmetric N-[(Phenylcarbonyl) carbamothioyl]benzamide Thiourea: Experimental and Theoretical Investigations

Rafael G. Silveira; Anderson J. L. Catão; Beatriz N. Cunha; Fernando Almeida; Rodrigo S. Correa; Luan F. Diniz; Juan C. Tenório; Javier Ellena; Aleksey E. Kuznetso; Alzir A. Batista; Edésio Alcântara

Simple synthesis path for obtaining a symmetric thiourea, the theoretical characterization and verification of the intermolecular interactions obtained by X-ray crystallography.


Published online: July 2, 2018.

J. Braz. Chem. Soc. 2018

Synthesis and Optical Properties of Water-Soluble CdTe:Zn2+ Quantum Dots Prepared by the One-Pot Approach

José C. L. Sousa; Marcelo G. Vivas; Jefferson L. Ferrari; Marco A. Schiavon

Color map representing the emission vs. excitation wavelengths for different synthesis times of CdTe:Zn2+ quantum dots (QDs), and the normalized characteristic emission spectra obtained from the evolving factor analysis/multivariate curve resolution alternating least squares (EFA/MCR-ALS) method for each QD solution show the different sizes of the nanoparticles.


Published online: July 2, 2018.

J. Braz. Chem. Soc. 2018

A Convenient Synthesis, Reactions and Biological Activity of Some New 6H-Pyrazolo[4',3':4,5]thieno[3,2-d][1,2,3]triazine Compounds as Antibacterial, Anti-Fungal and Anti-Inflammatory Agents

Remon M. Zaki; Adel M. Kamal El-Dean; Shaban M. Radwan; Ahmed F. Saber

In the present work, we have provided an easy access for synthesis of novel thienopyrazole compounds, which were used as starting materials for building new heterocyclic systems namely: pyrazole, triazole and triazine, attached or fused to the thienopyrazole moiety that have revealed remarkable antimicrobial and anti-inflammatory activities.


Published online: June 29, 2018.

J. Braz. Chem. Soc. 2018

Optimization of Acid Hydrolysis of Myricetin-3-O-rhamnoside Using Response Surface Methodology

Tatiana C. Tolosa; Hervé Rogez; Evaldo M. Silva; Jesus N. S. Souza

The acid hydrolysis of glycosylated flavonols were optimized and the hydrolytic process used is effective and applicable to plant extract (Inga edulis leaves).


Published online: June 26, 2018.

J. Braz. Chem. Soc. 2018

Voltammetric Determination of Zn2+ in Antiseptic Dusting Powder and Multivitamins Using a Carbon Paste Electrode Modified with Bi Anchored on Amberlite® IR120

Wilson T. Fonseca; Leandro A. R. Ribeiro; Lauro A. Pradela-Filho; Regina M. Takeuchi; André L. Santos

Carbon paste electrodes modified with Bi anchored on Amberlite® IR120 enable fast Zn2+ determination in multivitamin and antiseptic dusting powder samples.


Published online: June 26, 2018.

J. Braz. Chem. Soc. 2018

Assessment of Adulteration of Cosmetics Based on Vegetable Oils by GC-FID and Lipid Profile Using Direct Infusion Electrospray Ionization Mass Spectrometry (ESI-MS)

Jessica S. Pizzo; Marília B. Galuch; Patrícia D. S. Santos; Oscar O. Santos; Lorena Visentainer; Marcos N. Eberlind; Jesuí V. Visentainer

Vegetable oils have been applied to human skin for cosmetic purposes for a long time. However, they are targets of adulterations, especially with addition of oils with low cost. This study will evaluate the authenticity of Brazilian cosmetics based on vegetable oils.


Published online: June 25, 2018.

J. Braz. Chem. Soc. 2018

Electrochemical Deposition of the Single Phase TlxCu3 – xSe2 Thin Films

Francisco W. S. Lucas; Lucia H. Mascaro

TlCu2Se2 texturized film was electrodeposited with [004] crystalline plane oriented parallel to the substrate surface. This texturization can also be associated with the films morphology.


Published online: June 25, 2018.

J. Braz. Chem. Soc. 2018

Simultaneous Determination of Four Antibiotics in Raw Milk by UPLC-MS/MS Using Protein Precipitation as Sample Preparation: Development, Validation, and Application in Real Samples

Thiago Magon; Roberta da Silveira; Marília B. Galuch; Eder Paulo Fagan; Ana Flavia D. Feitoza; Sylvio V. Palombini; Oscar O. Santos; Jesui V. Visentainer

Determination of tetracycline, oxytetracycline, penicillin G and ceftiofur in raw milk by ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) using protein precipitation as sample preparation: development, validation, and application in raw milk samples from dairy cows medicated with tetracycline (24, 48, 72 and 96 h after treatment) for subclinical mastitis.


Published online: June 25, 2018.

J. Braz. Chem. Soc. 2018

Chemometric-Assisted Hydrophilic Interaction Chromatographic Method for the Determination of Gadolinium-Based Magnetic Resonance Imaging Contrast Agent in Liposomes

Ana Luiza C. Maia; Pedro Henrique R. da Silva; Christian Fernandes; Aline T. M. e Silva; André Luís B. de Barros; Daniel Crístian F. Soares; Gilson A. Ramaldes

Development, using chemometrics tools, of a hydrophilic interaction chromatographic method for the determination of gadodiamide in liposomes.


Published online: June 22, 2018.

J. Braz. Chem. Soc. 2018

Use of a Natural Sorbent as Alternative Solid-Phase Microextraction Coating for the Determination of Polycyclic Aromatic Hydrocarbons in Water Samples by Gas Chromatography-Mass Spectrometry

Natália G. Suterio; Sângela N. do Carmo; Dilma Budziak; Josias Merib; Eduardo Carasek

In this study, the use of a biosorbent-based coating in solid-phase microextraction was proposed for the determination of polycyclic aromatic hydrocarbons in water samples.


Published online: June 22, 2018.

J. Braz. Chem. Soc. 2018

Synthesis and Antibacterial Evaluation of 3,5-Diaryl-1,2,4‑oxadiazole Derivatives

Felipe S. Cunha; Joseli M. R. Nogueira; Alcino P. de Aguiar

Twenty 1,2,4-oxadiazole derivatives were synthesized and evaluated against five different bacteria.


Published online: June 20, 2018.

J. Braz. Chem. Soc. 2018

Preparation of Microcapsules of Slow-Release NPK Compound Fertilizer and the Release Characteristics

Wancheng Pang; Dejia Hou; Huan Wang; Shu Sai; Baorui Wang; Jingwen Ke; Gaobing Wu; Qing Li; Mark T. Holtzapple

The graphical abstract is an amplified structure of slow-release fertilizer. Microcapsule structure has disappeared after water soaking and the nutrient is slowly released completely.


Published online: June 19, 2018.

J. Braz. Chem. Soc. 2018

Oxidation of Single-Walled Carbon Nanotubes under Controlled Chemical Conditions

Arthur B. Porto; Glaura G. Silva; Hélio F. dos Santos; Luiz F. C. de Oliveira

Single-walled carbon nanotubes (SWCNT) are oxidized in acid medium under controlled NO2+ concentration and reaction time.


Published online: June 18, 2018.

J. Braz. Chem. Soc. 2018

Al-MCM-41 Synthesized from Kaolin via Hydrothermal Route: Structural Characterization and Use as an Efficient Adsorbent of Methylene Blue

Evânia C. Santos; Luelc S. Costa; Edipo S. Oliveira; Raquel A. Bessa; Armando D. L. Freitas; Cristiane P. Oliveira; Ronaldo F. Nascimento; Adonay R. Loiola

Natural kaolin is efficiently converted, via dealumination and hydrothermal route, to Al-Mobil Composition of Matter No. 41 (Al-MCM-41) mesoporous materials, with a high area surface, showing high performance on methylene blue adsorption from aqueous medium.


Published online: June 18, 2018.

J. Braz. Chem. Soc. 2018

Compound-Specific δ13C of n-Alkanes: Clean-Up Methods Appraisal and Application to Recent Sediments of a Highly Contaminated Bay

Milena Ceccopieri; Arthur L. Scofield; Lilian Almeida; Angela L. R. Wagener

The image summarizes the δ13C equation and the isotopic signature from different carbon sources in the Guanabara Bay, i.e., phytoplankton, mangrove trees, fossil fuel from boat traffic and industries.


Published online: June 14, 2018.

J. Braz. Chem. Soc. 2018

Geometry and Stability of Molecular Clusters: Factor to Be Considered in Biomolecular Activity

Noam G. da Silva; Alexandre M. Alecrim; Renyer A. Costa; Kelson M. T. de Oliveira

Molecular clusters are proposed as explanation for the different activities of betulinic and melaleucic acids, compounds with very similar properties.


Published online: June 12, 2018.

J. Braz. Chem. Soc. 2018

N-Alkylated Sulfamic Acid Derivatives as Organocatalyst in Multicomponent Synthesis of Fatty Dihydropyrimidinones

Carolina R. L. Hack; Larissa Porciuncula; Andressa C. H. Weber; Caroline R. M. D'Oca; Dennis Russowsky; Jaqueline M. Moura; Luiz A. A. Pinto; Marcelo G. M. D'Oca

N-Alkylated sulfamic acid derivatives are introduced as promising acidic organocatalysts in multicomponent reactions to the synthesis of dihydropyrimidinones.


Published online: June 11, 2018.

J. Braz. Chem. Soc. 2018

In-Line Incomplete Solid-Liquid Extraction for Spectrophotometric Determination of Soluble Inorganic Phosphorus in Plants and Foods

Caio C. V. Macedo; Rodrigo S. N. Mancini; Carolina Y. Arakaki; Diogo L. Rocha

Incomplete and reproducible soluble inorganic phosphorus extraction from vegetable materials and foods prior to spectrochemical analysis in a flow injection analysis (FIA) system with zones penetration.


Published online: June 8, 2018.

J. Braz. Chem. Soc. 2018

Automatic Procedure to Determine Acidity in Fuel Ethanol by Photometric Titration Using Binary Search and Multicommuted Flow Analysis

Manoel J. A. Lima; Boaventura F. Reis

A pictorial overview of the titration procedures for ethanol fuel employing manual and automatic approaches.


Published online: June 8, 2018.

J. Braz. Chem. Soc. 2018

Synthesis, Characterization and Evaluation of in vitro Antitumor Activities of Novel Chalcone-Quinolinone Hybrid Compounds

Giulio D. C. d'Oliveira; Andrea F. Moura; Manoel O. de Moraes; Caridad N. Perez; Luciano M. Lião

Chalcone-quinolinone synthesis: one step reaction, good yield and pure precipitate.


Published online: June 4, 2018.

J. Braz. Chem. Soc. 2018

Occurrence of Pesticides in Pericarpium Citri Reticulatae and Related Products Using Syringe Filter-Based Cleanup

Fuxin Liu; Xiaowen Dou; Jiaoyang Luo; Dandan Kong; Zhuowen Fan; Meihua Yang

Persistent organochlorines were found in commercial Pericarpium Citri Reticulatae by a "push-and-pull" needle filter based cleanup and gas chromatography (GC) analysis.


Published online: June 4, 2018.

J. Braz. Chem. Soc. 2018

Wastewater-Based Epidemiology of Cocaine in the Brazilian Federal District: Spatial Distribution, Weekly Variation and Sample Preservation Strategies

Fernando F. Sodré; Rafael S. Feitosa; Wilson F. Jardim; Adriano O. Maldaner

Cocaine use in the Brazilian Federal District, assessed by wastewater-based epidemiology (WBE), revealed higher consumption in the north area, notably during weekends. A nationwide survey may be carried out with sewage samples adjusted to pH 2 and transported within three days under ambient conditions.


Published online: May 29, 2018.

J. Braz. Chem. Soc. 2018

Exponential Fed-Batch Cultures of Klebsiella pneumoniae under Anaerobiosis Using Raw Glycerol as a Substrate to Obtain Value-Added Bioproducts

Allan Morcelli; Rosane Rech; Andre Klafke; Rafael Pelegrini; Marco A. Z. Ayub

Residual glycerol can be used as substrate in the production of valuable compounds by Klebsiella pneumonia in exponentially fed-batch cultures (EFBC).


Published online: May 29, 2018.

J. Braz. Chem. Soc. 2018

Mate as Dietary Supplement for Broiler Chickens: Effect on the Metabolic Profile and Redox Chemistry of Meat

Caroline Ceribeli; Andressa de Zawadzki; Aline M. C. Racanicci; Luiz A. Colnago; Leif H. Skibsted; Daniel R. Cardoso

Mate extract in animal diet improves the redox status of meat by changing its metabolic profile towards the production of endogenous antioxidants.


Published online: May 29, 2018.

J. Braz. Chem. Soc. 2018

Development, Optimization and Validation of a GC Method by Polarity Phase Constants and Statistical Design of Experiments for the Determination of Monoterpenes in Alpinia zerumbet Essential Oil

Igor C. Cardoso; Marcos J. Nakamura; Virginia G. Correia; Henrique M. G. Pereira; Maria D. Behrens; Marcelo R. R. Tappin

In this report, we described the optimization by response surface methodology of a new analytical method by gas chromatography (GC) for analysis of Alpinia zerumbet essential oil.


Published online: May 29, 2018.

J. Braz. Chem. Soc. 2018

Study of the Naphthenic Corrosion of AISI 316 and AISI 1020 Steels by Light, Scanning Electron and Atomic Force Microscopies (LM, SEM and AFM)

Débora V. Domingos; Fabrício C. Tozzi; Eliane V. Barros; Fernanda E. Pinto; Cristina M. S. Sad; Paulo R. Filgueiras; Valdemar Lacerda Jr.; Heloisa P. Dias; Glória M. V. F. Aquije; Wanderson Romão

AISI 316 and AISI 1020 steel coupons were analyzed by scanning electron microscopy (SEM) and atomic force microscopy (AFM) before and after immersion in various crude oil samples and their respective blends for 48 days at room temperature.


Published online: May 25, 2018.

J. Braz. Chem. Soc. 2018

Effect of Calcination Temperature on Catalytic Performance of CeCu Oxide in Removal of Quinoline by Wet Hydrogen Peroxide Oxidation from Water

Zhaojie Jiao; Guilin Zhou; Haidong Zhang; Yu Shen; Xianming Zhang; Juexuan Li; Xu Gao

The CeCu-mixed oxide catalyst calcinated at temperature of 650 °C took on the best performance with an oxidation conversion up to 98% for quinoline, a removal efficiency of 80.6% for total organic carbon (TOC) and a low Cu2+ leaching value of 19.3 mg L-1.


Published online: May 25, 2018.

J. Braz. Chem. Soc. 2018

Air Quality in the Maracanã and Deodoro Zones During the Rio 2016 Olympic Games

Carolina A. Bezerra; Nicole J. de Carvalho; Claudio G. P. Geraldino; Cleyton M. da Silva; Graciela Arbilla

C4-C12 non-oxygenated volatile organic compounds and criteria pollutants were analyzed during the Rio de Janeiro Summer 2016 Olympic Games, in two Olympic zones, Maracanã (Tijuca) and Deodoro.


Published online: May 22, 2018.

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
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