JBCS

1:58, Wed Nov 22

Open Access/APCs

vol. 23, No. 10, 2012, p. 1767-1954

 

G-Protein-Coupled Receptors: the 2012 Nobel Prize in Chemistry

The Royal Swedish Academy of Sciences awarded the 2012 Nobel Prize in Chemistry to the U.S. researchers Robert J. Lefkowitz, from the Duke University Medical Center (North Carolina, USA) and to Brian K. Kobilka, from the Stanford University School of Medicine (California, USA) for their studies on the G-proteincoupled receptors (GPCRs).

(Read more at Editorial)


Cover Article
J. Braz. Chem. Soc. 2012, 23(10), 1807-1814

Suppression of the Hemolytic Effect of Mesoporous Silica Nanoparticles after Protein Corona Interaction: Independence of the Surface Microchemical Environment

Amauri J. Paula; Diego Stéfani T. Martinez; Roberto T. Araujo Júnior; Antonio G. Souza Filho; Oswaldo L. Alves

How to cite this article

The effects induced by nanoparticles interacting in biological fluids and with blood cells were determined by fine and selective chemical interactions between these materials in nanoscale and biomolecules. In this context, understanding and controlling these interactions will be crucial to pave the way towards the application of nanomaterials in nanomedicine and nanotoxicology. Details are discussed in the Article by Paula et al. on page 1807.

http://dx.doi.org/10.1590/S0103-50532012005000048

Published online: October 2, 2012

Editorial J. Braz. Chem. Soc. 2012, 23(10), 1767-1770

G-Protein-Coupled Receptors: the 2012 Nobel Prize in Chemistry

Adriano D. Andricopulo; Glaucius Oliva

How to cite this article

 

http://dx.doi.org/10.1590/S0103-50532012001000001


Articles J. Braz. Chem. Soc. 2012, 23(10), 1772-1775

Synthesis, Crystal Structure and Biological Activity of Novel Diester Cyclophanes

Pengfei Zhang; Bingqin Yang; Xianwen Fang; Zhao Cheng; Meipan Yang

How to cite this article

 

Several novel cyclophanes were synthesized by esterification reactions under high dilution conditions. Some of these compounds have low antifungal or antibacterial activities

http://dx.doi.org/10.1590/S0103-50532012005000045

Published online: September 25, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1776-1782

Spatial Structure of Eugenia dysenterica Based on Essential Oil Chemovariations and Implications for Conservation and Management of the Genetic Diversity of its Populations

Eliane C. Vilela; Thays C. Carvalho; Alessandra R. Duarte; Ronaldo R. Naves; Suzana C. Santos; José C. Seraphinc; Pedro H. Ferri

How to cite this article

 

Essential oils were used to study the spatial structure of eight Eugenia dysenterica populations in central Brazilian Cerrado. Differential patterns can be explained by the distinct spatial rearrangement of the populations and may contribute to the species management and conservation based only on oil chemovariations

http://dx.doi.org/10.1590/S0103-50532012005000043

Published online: September 25, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1783-1788

Biosynthesis of Two Dihydropyrrole-Polyketides from a Marine-Derived Penicillium citrinum

Stelamar Romminger; Eli F. Pimenta; Eduardo S. Nascimento; Antonio G. Ferreira; Roberto G. S. Berlinck

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Feeding experiments using 13C-labeled precursors were performed aim at investigating the biosynthesis of two dihydropyrrole-polyketides isolated from a marine-derived Penicillium citrinum. The results showed that the biosynthesis proceeds from acetate, methionine and ornithine

http://dx.doi.org/10.1590/S0103-50532012005000046

Published online: September 28, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1789-1799

Probing Topological Electronic Effects in Catalysis: Thiophene Adsorption on NiMoS and CoMoS Clusters

Itamar Borges Jr.; Alexander M. Silvab

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Thiophene adsorbed on NiMoS and CoMoS catalysts was studied with density functional theory and a topological approach to probe electronic modifications. The origin of the promoter effect, an enhancement of hydrodesulfurization activity due to weaking of metal-sulfur bond strengths, was explained

http://dx.doi.org/10.1590/S0103-50532012005000044

Published online: September 28, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1800-1806

Determination of Sildenafil Citrate (Viagra®) in Various Pharmaceutical Formulations by Flow Injection Analysis with Multiple Pulse Amperometric Detection

Antônio Carlos V. Lopes Júnior; Rita de Cássia Silva Luz; Flávio S. Damos; Alexandre S. dos Santos; Diego L. Francoe; Wallans T. Pio dos Santos

How to cite this article

 

Fast and low-cost methodology for the determination of sildenafil in different types of pharmaceutical samples using a flow injection analysis (FIA) system with multiple pulse amperometric detection on a boron-doped diamond electrode is presented. Excellent reproducibility and high analytical frequency were obtained under these conditions

http://dx.doi.org/10.1590/S0103-50532012005000047

Published online: September 28, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1807-1814

Suppression of the Hemolytic Effect of Mesoporous Silica Nanoparticles after Protein Corona Interaction: Independence of the Surface Microchemical Environment

Amauri J. Paula; Diego Stéfani T. Martinez; Roberto T. Araujo Júnior; Antonio G. Souza Filho; Oswaldo L. Alves

How to cite this article

 

Bare porous silica nanoparticles induce hemolysis in human red blood cells, while protein coated nanoparticles resulted from their interaction with blood plasma (the so called protein corona effect) completely prevent the hemolytic effect

http://dx.doi.org/10.1590/S0103-50532012005000048

Published online: October 2, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1815-1822

Evaluation of Chemical Changes during Myrciaria cauliflora (Jabuticaba Fruit) Fermentation by 1H NMR Spectroscopy and Chemometric Analyses

Gilmara A. C. Fortes; Sara S. Naves; Pedro H. Ferri; Suzana C. Santos

How to cite this article

 

Metabolites were monitored during jabuticaba fermentation by 1H nuclear magnetic resonance and spectrophotometric assays. Multivariate methods revealed the influences of alcohols and organic acids on the extraction and stability of phenols and color properties

http://dx.doi.org/10.1590/S0103-50532012005000050

Published online: October 2, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1823-1833

Influence of Abiotic Factors on the Chemical Composition of Copaiba Oil (Copaifera multijuga Hayne): Soil Composition, Seasonality and Diameter at Breast Height

Paula C. S. Barbosa; Raquel S. Medeiros; Paulo T. B. Sampaio; Gil Vieira; Larissa S. M. Wiedemanna; Valdir F. Veiga-Junior

How to cite this article

 

The chemical composition of copaiba oils (Copaifera multijuga Hayne) is affected by soil characteristics, but not seasonality or diameter at breast height (DBH). Cluster analysis shows that caryophyllene and its oxide form the main groups

http://dx.doi.org/10.1590/S0103-50532012005000049

Published online: October 5, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1834-1838

Fast Determination of Naproxen in Pharmaceutical Formulations by Batch Injection Analysis with Pulsed Amperometric Detection

Jessica S. Stefano; Ana Paula de Lima; Rodrigo H. O. Montes; Eduardo M. Richter; Rodrigo A. A. Muñoz

How to cite this article

 

A fast method for naproxen determination in pharmaceutical formulations using batch injection analysis with pulsed amperometric detection is presented. High analytical frequency (90 h-1), satisfactory accuracy and low limit of detection (0.3 µmol L-1) were obtained

http://dx.doi.org/10.1590/S0103-50532012005000055

Published online: October 9, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1839-1843

Synthesis of N-Substituted Phthalimidoalkyl 1H-1,2,3-Triazoles: a Molecular Diversity Combining Click Chemistry and Ultrasound Irradiation

Moara T. da Silva; Ronaldo N. de Oliveira; Wagner O. Valença; Fernanda C. G. Barbosa; Mauro G. da Silva; Celso A. Camara

How to cite this article

 

N-substituted phthalimidoalkyl 1H-1,2,3-triazoles were obtained in good-to-excellent yields (67-98%) through click chemistry protocol (Cu-AAC) at room temperature using DMF, Et3N under ultrasound irradiation

http://dx.doi.org/10.1590/S0103-50532012005000053

Published online: October 11, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1844-1852

Chemotaxonomic Markers in Essential Oils of Hypenia (Mart. ex Benth.) R. Harley

Maria T. Faria; Deomar P. Costa; Eliane C. Vilela; Dalva G. Ribeiro; Heleno D. Ferreira; Suzana C. Santos; José C. Seraphind; Pedro H. Ferri

How to cite this article

 

Essential oil chemovariations in the genus Hypenia suggest that cadinanes and bicyclo-germacranes/aromadendranes are chemomarkers of sections Densiflorae and Laxiflorae, respectively

http://dx.doi.org/10.1590/S0103-50532012005000056

Published online: October 11, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1853-1857

7,8-Secolignans from Schisandra neglecta and Their Anti-HIV-1 Activities

Xuemei Gao; Huaixue Mu; Ruirui Wang; Qiufen Hu; Liumeng Yang; Yongtang Zheng; Handong Sunb; Weilie Xiao

How to cite this article

 

Four new 7,8-secolignans (neglectahenols A-D) were isolated from leaves and stems of Schisandra neglecta, and neglectahenols A-D showed modest anti HIV-1 (human immuno-deficiency virus type 1) activities with therapeutic index (TI) values of 58.65, 26.36, 23.71 and 25.85, respectively

http://dx.doi.org/10.1590/S0103-50532012005000054

Published online: October 11, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1858-1862

Synthesis of LaNiO3 Perovskite by the Modified Proteic Gel Method and Study of Catalytic Properties in the Syngas Production

José C. Santos; Marcelo J. B. Souza; Juan A. C. Ruiz; Dulce M. A. Melo; Maria E. Mesquitaa; Anne M. Garrido Pedrosa

How to cite this article

 

The temperature programmed reduction analysis of LaNiO3 and LaNiO3/Al2O3 showed that the Ni3+ of perovskite structure reduced in two steps and the peaks correspond to successive changes in the structure, which are related to reduction: Ni3+ to Ni2+ and Ni2+ to Ni0

http://dx.doi.org/10.1590/S0103-50532012005000052

Published online: October 11, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1863-1870

Decolorization of Textile Dyes by Cyanobacteria

Maria Estela Silva-Stenico; Felipe D. P. Vieira; Diego B. Genuário; Caroline S. P. Silva; Luiz Alberto B. Moraes; Marli Fátima Fiore

How to cite this article

 

The use of cyanobacteria to decolorize and possibly to degrade eleven types of textile dyes was confirmed by mass spectrometry and resulted in completely textile dye remotion

http://dx.doi.org/10.1590/S0103-50532012005000058

Published online: October 16, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1871-1879

Solar Radiation Effect on the Complexation Capacity of Aquatic Humic Substances with Metals

Camila A. Melo; Ana L. De Toffoli; Altair B. Moreira; Márcia C. Bisinoti

How to cite this article

 

The effect of solar radiation in the complexation capacity of aquatic humic substances (AHS) with Al3+, Cr3+, CrO42- and Ni2+ was evaluated. AHS were extracted and characterized employing conventional techniques

http://dx.doi.org/10.1590/S0103-50532012005000059

Published online: October 19, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1880-1888

A Study of Asphaltene-Resin Interactions

Luiz C. C. Marques; Juliana O. Pereira; André D. Bueno; Valdo S. Marques; Elizabete F. Lucas; Claudia R. E. Mansur; André L. C. Machado; Gaspar González

How to cite this article

 

Asphaltic materials recovered from a subsea petroleum production flowline during a pigging operation in Santos Basin, Santa Catarina State, Brazil

http://dx.doi.org/10.1590/S0103-50532012005000060

Published online: October 19, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1889-1894

Simultaneous Separation of Ciprofloxacin, Norfloxacin and Ofloxacin by Micellar Electrokinetic Chromatography

Gabriel Hancu; Aura Rusu; Brigitta Simon; Georgiana Boia; Árpád Gyéresi

How to cite this article

 

The article studies the electrophoretic behavior of the most frequently used fluoroquinolones (structurally related ciprofloxacin, norfloxacin and ofloxacin) in order to achieve their simultaneous separation from complex mixtures, by means of capillary zone electrophoresis respectively MEKC

http://dx.doi.org/10.1590/S0103-50532012005000057

Published online: October 19, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1895-1899

A Simple Method to Evaluate, Correlate and Predict Boiling and Flash Points of Alkynes

Justin M. Godinho; Felix A. Carroll; Frank H. Quina

How to cite this article

 

Experimental boiling point numbers (YBP) of alkynes can be used to evaluate literature boiling point data, and YBP values calculated from simple structure counts can be used to predict alkyne boiling and flash points

http://dx.doi.org/10.1590/S0103-50532012005000064

Published online: October 23, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1900-1906

Photocatalytic Decomposition of Phenol by Nanocomposite of ZnS Nanoparticles and Montmorillonite

Petr Praus; Jakub Matys; Ondřej Kozák

How to cite this article

 

ZnS nanoparticles were deposited on montmorillonite forming a stable nanocomposite, which was used as a catalyst for the photodecomposition of phenol. Reaction kinetics agreed with the pseudo-first reaction model confirming that the high amounts of hydroxyl radicals were produced. The catalytic activity of montmorillonite was not observed

http://dx.doi.org/10.1590/S0103-50532012005000063

Published online: October 23, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1907-1914

Absolute Quantification of Fatty Acid and Proximate Composition of Cow and Goat Powdered Milks

Weliton P. Batiston; Swami A. Maruyama; Sandra T. M. Gomes; Jesuí V. Visentainer; Nilson E. de Souza; Makoto Matsushita

How to cite this article

 

Thermal processes applied in foods can lead to a loss of their nutritional quality due to the oxidation of their polyunsaturated fatty acids. Thus, the main objective of the present study is the absolute quantification of fatty acids from cow and goat powdered milks, through the application of gas chromatography with a flame ionization detector (GC-FID)

http://dx.doi.org/10.1590/S0103-50532012005000061

Published online: October 26, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1915-1924

Seasonal Distribution of Airborne Trace Elements and Water-Soluble Ions in São Paulo Megacity, Brazil

Gisele O. Da Rocha; Pérola C. Vasconcellos; Simone G. Ávila; Davi Z. Souza; Eduardo A. O. Reis; Pedro V. Oliveira; Odon Sanchez-Ccoyllo

How to cite this article

 

This work describes the seasonal distribution of important constituents of PM10 particles (particulate matter less than 10 μm in diameter; major ions and trace elements) in São Paulo Megacity, Brazil. Predominant sources were fuel burning, biomass burning, gas-to-particle conversion and sea salt spray

http://dx.doi.org/10.1590/S0103-50532012005000062

Published online: October 26, 2012

J. Braz. Chem. Soc. 2012, 23(10), 1925-1932

Chemical Constituents from Chirita longgangensis var. hongyao with Inhibitory Activity against Porcine Respiratory and Reproductive Syndrome Virus

Yao Su; Jun-Long Bi; Yue-Hu Wang; Ying Tan; Jun Yang; Hong-Xin Liu; Wei Gu; Ge-Fen Yin; Chun-Lin Long

How to cite this article

 

Two new quinonoids and a new neolignan were isolated from stems of Chirita longgangensis var. hongyao

http://dx.doi.org/10.1590/S0103-50532012005000068

Published online: October 30, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1934-1939

Flavonoids from the Leaves of Deguelia utilis (Leguminosae): Structural Elucidation and Neuroprotective Properties

Dalglish G. de Oliveira; Cecília M. C. de Almeida; Consuelo Y. Y. e Silva; Mara S. P. Arruda; Alberto C. Arruda; Dielly C. F. Lopes; Elizabeth S. Yamada; Edmar T. da Costa; Milton N. da Silva

How to cite this article

 

Five new compounds were isolated from the leaves of Deguelia utilis. A fraction containing all flavonoids was available to determine its neuroprotective action

http://dx.doi.org/10.1590/S0103-50532012005000065

Published online: November 1, 2012


J. Braz. Chem. Soc. 2012, 23(10), 1940-1950

Three New Labdanes Isolated from Eragrostis viscosa

N'Soki N. Sebastião; Nelson Fernandes; Liliana Vieira; António J. G. Mendonça; Jorge F. Gaspar; Celia Martins; José Rueff; Carlos Diakanamwa; Dina I. M. D. de Mendonça

How to cite this article

 

Three new labdanes methyl 8α,15-epoxylabdan-16β-oate, 8α,15-epoxylabdan-16β-ol and 8α,15-epoxy-16-norlabdan-13β-ol together with three known 8α,15-epoxylabdanes and two triterpenes were isolated from Eragrostis viscosa. 8α,15-Epoxylabdan-16β-ol was shown to be the most cytotoxic of the compounds tested

http://dx.doi.org/10.1590/S0103-50532012005000067

Published online: November 1, 2012


Short Reports J. Braz. Chem. Soc. 2012, 23(10), 1951-1954

Ionic Liquid Catalyzed Convenient Synthesis of Imidazo[1,2-α]quinoline under Sonic Condition

Devji S. Patel; Jemin R. Avalani; Dipak K. Raval

How to cite this article

 

http://dx.doi.org/10.1590/S0103-50532012005000051

Published online: October 5, 2012

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
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