JBCS

A method for determination of nimesulide, amitriptyline, enalapril, glibenclamide, haloperidol and methylparaben in water samples using a solid-phase extraction and liquid chromatography tandem mass spectrometry is presented. Good accuracy and precision were obtained.

Novel β-aminoketones and γ-aminoalcohols showing a wide structural diversity were easily obtained through a simple approach by using 3-(N,N-dimethylamino)propiophenone derivatives as key starting material. This protocol proved to be convenient as an alternative route for the synthesis of the local anesthetic Falicain^® and for the topic antifungal drug Naftifine^®.

Oils and grease are important parameters for water quality and safety. A Fourier transform infrared method with tetrachloroethylene was implemented and validated, and this extraction solvent was a suitable replacement to Freon 113.

A protocol for the Prins cyclization under mild and metal-free conditions is described.

A series of naphthoquinone diynes containing aryl, alkyl, hydroxyalkyl and derivatives were synthesized. These compounds were evaluated for cytotoxicity against three tumor cell lines, presenting satisfactory results for cell growth inhibition.

This work describes kinetic resolutions of (±)-β-azidophenylethanols, the enantiomerically enriched (R)-β-azidophenylethanols were subjected to cyclization reaction producing chiral 1,2,3-benzotriazole compounds in good yields.

A fractional factorial design was used to optimize the procedure for solid-phase extraction to achieve reliable, quick and optimal conditions. Recovery and precision were improved with the optimized conditions for all analyzed compounds (benzophenone-3, ethylhexyl methoxycinnamate, ethylhexyl salicylate and octocrylene) for river and drinking water.

In this study, it was possible to directly relate the metal extracted by devices based on the technique of diffusion gradients in thin films (DGT) with the available metal with CaCl₂ or the metal bound to soil organic matter.

Toxicity reduction (74%) in aqueous solutions containing glyphosate after photocatalytic treatment using photo-Fenton process

A screen-printed electrode based on a graphite and polyurethane resin composite (EIGPU) was applied in the simultaneous determination of acetaminophen and caffeine in pharmaceutical samples analysis. In good agreement with the declared lable contents as well as HPLC results. The figure depicts the DPV curve of a solution containing both analytes at the EIGPU under optimized conditions as described in the text.

The studentized residual plot of the ordinary least squares regression (OLSM) does not show homoscedastic variance since response variance increases with the mean response, violating the OLSM assumptions. With WLSM approach adoption, the heteroscedasticity problem was corrected by using different weights for the observations.

The ergosterol determination by high performance liquid chromatography-tandem mass spectrometry as a sensitive indicator of fungal contamination of building materials is presented. The presence of fungi was confirmed with the use of electron microscope and bioluminescence measurements.

The effects of the pseudoaxial substituents (L) on the lability of {Ru—NO}⁶ bond in nitrosyl-[poly(1-pyrazolyl)borate]ruthenium complexes are investigated at the light of energy decomposition analysis (Su-Li EDA).

This work describes a new synthesis of (—)-(R)- and (+)-(S)-angustureine enantiomers from a racemic β-amino ester controlled by kinetic enzymatic resolution. Synthesis of both alkaloids was achieved in good yields and excellent enantiomeric excesses.

A cathodically pretreated boron-doped diamond electrode and differential pulse voltammetry are used to determine propylthiouracil (PTU). For the first time in the literature, a non-modified solid electrode is used to analyze PTU in pharmaceutical formulations, with results in agreement with those of a comparative titration method.

Si-Zr/Ti(PMTDS) is a new stationary phase for reversed-phase high-performance liquid chromatography that presents retention properties similar to those zirconized silica-based PMTDS phases and hydrolytical stability similar to those titanized silica-based PMTDS phases.

This work determined proximate/fatty acid compositions and antioxidant activity of breads using a Box-Behnken design composed of fifteen experiments and three factors. The studied breads had altered baking times and the wheat flour used was partially substituted by chia seeds and carrot leaves.

A simple and fast method was developed for the determination of BTEX (benzene, toluene, ethylbenzene and xylene) in solid waste and solutions obtained from leaching applying procedures detailed in the ABNT NBR 10004/2004Brazilian standard for the classification of solid residues.

This work describes recycling of citrus processing waste from oranges (CPWO) and a production of: essential oil, bioethanol and nanocellulose. This work also explores fermentation abilities of microorganisms isolated from the target biomass.

A new benzofuran neolignan, dihydrodehydrodiconiferyl alcohol 9-isovalerate, along with ten known phenolic compounds were isolated from the roots of Valeriana officinalis var. latifolia.