JBCS

15:34, Mon Jul 24

Open Access/APCs

vol. 27, No. 11, 2016, p. 1925-2159

 

A drug delivery system based on biocellulose (BC) membranes containing a photosensitizer, chloroaluminum phthalocyanine (ClAlPc), with promising applications in localized topical administration in photodynamic therapy (PDT) is introduced. The non-cytotoxic system is capable to perform the light-induced generation of a reactive oxygen specie (ROS), singlet oxygen (1O2), one of the main agents in PDT. Details are presented in the Article Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer by Maristela F. S. Peres, Karina Nigoghossian, Fernando L. Primo, Sybele Saska, Ticiana S. O. Capote, Raquel M. S. Caminaga, Younes Messaddeq, Sidney J. L. Ribeiro and Antonio C. Tedesco on page 1949.


Cover Article
J. Braz. Chem. Soc. 2016, 27(11), 1949-1959

Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer

Maristela F. S. Peres; Karina Nigoghossian; Fernando L. Primo; Sybele Saska; Ticiana S. O. Capote; Raquel M. S. Caminaga; Younes Messaddeq; Sidney J. L. Ribeiro; Antonio C. Tedesco

How to cite this article

A drug delivery system based on biocellulose (BC) membranes containing a photosensitizer, chloroaluminum phthalocyanine (ClAlPc), with promising applications in localized topical administration in photodynamic therapy (PDT) is introduced. The non-cytotoxic system is capable to perform the light-induced generation of a reactive oxygen specie (ROS), singlet oxygen (1O2), one of the main agents in PDT. Details are presented in the Article Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer by Maristela F. S. Peres, Karina Nigoghossian, Fernando L. Primo, Sybele Saska, Ticiana S. O. Capote, Raquel M. S. Caminaga, Younes Messaddeq, Sidney J. L. Ribeiro and Antonio C. Tedesco on page 1949.

http://dx.doi.org/10.5935/0103-5053.20160080

Published online: March 17, 2016

Articles J. Braz. Chem. Soc. 2016, 27(11), 1925-1937

NMR Studies on [2 + 3] Cycloaddition of Nitrile Oxides to Polyunsaturated Medium Size Rings

Mirosław Gucma; W. Marek Gołębiewski; Alicja K. Michalczyk

How to cite this article

 

High regio- and site selectivity of [2 + 3] dipolar cycloaddition reaction of 4-trifluoromethylbenzonitrile oxide to C15 sesquiterpene was observed

http://dx.doi.org/10.5935/0103-5053.20160078

Published online: March 16, 2016


J. Braz. Chem. Soc. 2016, 27(11), 1938-1948

Distribution of Xanthene Dyes in DPPC Vesicles: Rationally Accounting for Drug Partitioning Using a Membrane Model

Italo R. Calori; Diogo S. Pellosi; Douglas Vanzin; Gabriel B. Cesar; Paulo C. S. Pereira; Mario J. Politi; Noboru Hioka; Wilker Caetano

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Distribution of xanthene dyes in 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) vesicles.

http://dx.doi.org/10.5935/0103-5053.20160079

Published online: March 17, 2016


J. Braz. Chem. Soc. 2016, 27(11), 1949-1959

Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer

Maristela F. S. Peres; Karina Nigoghossian; Fernando L. Primo; Sybele Saska; Ticiana S. O. Capote; Raquel M. S. Caminaga; Younes Messaddeq; Sidney J. L. Ribeiro; Antonio C. Tedesco

How to cite this article

 

The bacterial cellulose (BC)-chloroaluminum phthalocyanine (ClAlPc) membranes were evaluated as a potential drug delivery system for photodynamic therapy of skin cancer.

http://dx.doi.org/10.5935/0103-5053.20160080

Published online: March 17, 2016

J. Braz. Chem. Soc. 2016, 27(11), 1960-1965

Development of Surface Plasmon Resonance-Based Immunosensor for Detection of Brucella melitensis

Fatemeh Saberi; Mehdi Kamali; Ramezan A. Taheri; Mahdi F. Ramandi; Samira Bagdeli; Reza Mirnejad

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Production and purification of recombinant protein/immunization of rabbit and antibody purification/immobilization of antibody on sensor chip/interaction of bacteria with immobilized antibody/analyzing of responses.

http://dx.doi.org/10.5935/0103-5053.20160085

Published online: March 21, 2016

J. Braz. Chem. Soc. 2016, 27(11), 1966-1973

Optimizing Labeling Conditions for Cysteine-Based Peptides with 99mTc

Hamideh Sabahnoo; Seyed Jalal Hosseinimehr

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We optimized radiolabeling cysteine-based peptides with technetium-99m (99mTc). In this study, the effect of experimental parameters in the labeling procedure such as type of buffer solutions, pH of media, and type of exchange ligands were optimized toward obtaining maximum labeling yield.

http://dx.doi.org/10.5935/0103-5053.20160086

Published online: March 21, 2016


J. Braz. Chem. Soc. 2016, 27(11), 1974-1979

A Systematic Procedure to Develop a Capillary Electrophoresis Method Using a Minimal Experimental Data

Daniel A. Spudeit; Samantha Gonçalves; Lizandra C. Bretanha; Carlos A. Claumann; Ricardo A. F. Machado; Gustavo A. Micke

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The use of a curve of mobility vs. pH to optimize the optimum background electrolyte (BGE) composition that leads to a reduced analysis time.

http://dx.doi.org/10.5935/0103-5053.20160087

Published online: March 21, 2016

J. Braz. Chem. Soc. 2016, 27(11), 1980-1988

Estimating the Time-Dependent Performance of Nanocatalysts in Fuel Cells Based on a Cost-Normalization Approach

Cinthia R. Zanata; Pablo S. Fernández; Alexandre B. Santos; Gabriel C. da Silva; Giuseppe A. Camara; Cauê A. Martins

How to cite this article

 

A new method to normalize power of fuel cells based on the cost of metals. This method allows the forecasting of power density.

http://dx.doi.org/10.5935/0103-5053.20160088

Published online: March 22, 2016


J. Braz. Chem. Soc. 2016, 27(11), 1989-1997

Effects of the Peripheral Heteroaryl Substituents on the Photochromism of New Pyridine-Containing Diarylethenes

Guanming Liao; Dandan Xue; Chunhong Zheng; Renjie Wang; Shouzhi Pu

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Three new unsymmetrical diarylethenes were synthesized, exhibiting a notable photochromism. Diarylethenes with thienyl/thiazyl unit showed higher photocyclization quantum yield than that with phenyl moiety, which was ascribed to the existing weak N...S heteroatom-contact.

http://dx.doi.org/10.5935/0103-5053.20160089

Published online: March 22, 2016


J. Braz. Chem. Soc. 2016, 27(11), 1998-2010

Design, Synthesis, Pharmacological Evaluation and Molecular Docking Studies of Substituted Oxadiazolyl-2-Oxoindolinylidene Propane Hydrazide Derivatives

Deweshri Kerzare; Rupesh Chikhale; Ratnadeep Bansode; Nikhil Amnerkar; Nazira Karodia; Anant Paradkar; Pramod Khedekar

How to cite this article

 

A series of oxadiazolyl-2-oxoindolinylidene propane hydrazides were synthesized based on hybrid approach. Two compounds from this series exhibited good analgesic and anti-inflammatory activity with better protection compared to indomethacin. These compounds also exhibited good dock score of about -4.44 by the K-nearest neighbors (KNN)-genetic algorithm method.

http://dx.doi.org/10.5935/0103-5053.20160090

Published online: March 22, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2011-2020

Electrochemical Investigations of Li2Fe0.8-xMn0.2MxSiO4 (M = Mg2+, Zn2+) Cathodes for Lithium Ion Batteries

Shu-Dan Li; Yun Zhao; Chen-Yi Wang; Kun Gao

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After the co-doping result in the increasing area of oxidation peak around 3.5 V. At the same time, a shift of reduction peak at 2.5 V towards the right means less internal polarization.

http://dx.doi.org/10.5935/0103-5053.20160091

Published online: March 23, 2016

J. Braz. Chem. Soc. 2016, 27(11), 2021-2033

Method Development and Total Uncertainty Estimation for Boron, Sulfur and Phosphorus Determination in Mineral Fertilizer Using ICP OES

Tiago C. de Oliveira; Roger T. Rampazzo; Marco F. Ferrão; Dirce Pozebon

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Relative contribution of each factor to the total uncertainty in the determination of boron, phosphorus and sulfur in mineral fertilizer by inductively coupled plasma optical emission spectrometry.

http://dx.doi.org/10.5935/0103-5053.20160092

Published online: March 23, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2034-2045

Integrated Synthesis of Zeolites Using Coal Fly Ash: Element Distribution in the Products, Washing Waters and Effluent

Suzana F. Ferrarini; Ariela M. Cardoso; Alexandre Paprocki; Marçal Pires

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The mobilization of several elements of coal fly ash to end products, washing waters and the effluent of the zeolite two-steps synthesis, was evaluated. The presence of highly toxic elements (As, Cd, Cr, Ni and Pb) in the end products indicates the need for pre-treatment of the ash to ensure a safe zeolite application.

http://dx.doi.org/10.5935/0103-5053.20160093

Published online: March 29, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2046-2054

Selective Synthesis of (Z)-Chalcogenoenynes and (Z,Z)-1,4-bis-Chalcogenbuta-1,3-dienes Using PEG-400

Renata G. Lara; Liane K. Soares; Raquel G. Jacob; Ricardo F. Schumacher; Gelson Perin

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The selective synthesis of (Z)-chalcogenoenynes and (Z,Z)-1,4-bis-chalcogenbuta-1,3-dienes is presented here.

http://dx.doi.org/10.5935/0103-5053.20160094

Published online: March 29, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2055-2061

How Accurate is the SMD Model for Predicting Free Energy Barriers for Nucleophilic Substitution Reactions in Polar Protic and Dipolar Aprotic Solvents?

Elizabeth L. M. Miguel, Calink I. L. Santos, Carlos M. Silva and Josefredo R. Pliego Jr.

How to cite this article

 

The solvent model density (SMD) model is not able to predict the protic to dipolar aprotic solvent rate acceleration effect for ion-molecule nucleophilic substitution reactions.

http://dx.doi.org/10.5935/0103-5053.20160095

Published online: March 30, 2016

J. Braz. Chem. Soc. 2016, 27(11), 2062-2069

The Effect of Gamma-Al2O3 Support on the NO Adsorption on Pd4 Cluster

Letícia M. Prates; Glaucio B. Ferreira; José W. M. Carneiro; Wagner B. de Almeida; Alexandre N. M. Carauta; Julio C. G. Correia; Maurício T. M. Cruz

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Distortion of Pd4 promoted by γ-alumina cluster (top) and preferential site for adsorption of NO on Pd4/Al14O24H6 (bottom).

http://dx.doi.org/10.5935/0103-5053.20160096

Published online: March 30, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2070-2075

Fighting Collinearity in QSPR Equations for Solution Kinetics with the Monte Carlo Method and Total Weighting

Ruben A. Elvas-Leitão

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Comparison between computed confidence intervals for ln k = f(x1, x2, x3) regression coefficients.

http://dx.doi.org/10.5935/0103-5053.20160097

Published online: March 31, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2076-2081

Evaluation of Inductively Coupled Plasma Tandem Mass Spectrometry for Determination of As in Agricultural Inputs with High REE Contents

Raquel C. Machado; Alex Virgilio; Clarice D. B. Amaral; Daniela Schiavo; Joaquim A. Nóbrega; Ana Rita A. Nogueira

How to cite this article

 

Inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) as an effective tool to overcome double charged interferences from rare earth elements (REEs) on As determination in agricultural inputs.

http://dx.doi.org/10.5935/0103-5053.20160098

Published online: March 31, 2016

J. Braz. Chem. Soc. 2016, 27(11), 2082-2092

A New Post-Metallocene-Ti Catalyst with Maltolate Bidentade Ligand: an Investigation in Heterogeneous Polymerization Reactions in Different Mesoporous Supports

Grasiela Gheno; Nara Regina de Souza Basso; Paolo Roberto Livotto; Maria Rosário Ribeiro; João Paulo Lourenço; Ana Elisa Ferreira; Griselda Barrera Galland

How to cite this article

 

A new post-metallocene-Ti catalyst with ethylmaltol ligand was synthesized and characterized. This complex was immobilized on different mesoporous supports and investigated in ethylene polymerization reaction giving high density polyethylene.

http://dx.doi.org/10.5935/0103-5053.20160099

Published online: April 1, 2016

J. Braz. Chem. Soc. 2016, 27(11), 2093-2104

Yerba Mate Tea Extract: a Green Approach for the Synthesis of Silica Supported Iron Nanoparticles for Dye Degradation

Natália S. F. Trotte; Mariana T. G. Aben-Athar; Nakédia M. F. Carvalho

How to cite this article

 

Iron nanoparticles were prepared from yerba mate tea extract by a green synthetic approach and successfully applied in the degradation of the dye methyl orange.

http://dx.doi.org/10.5935/0103-5053.20160100

Published online: April 4, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2105-2113

Mixed-Hemimicelle Solid Phase Extraction Followed by Dispersive Liquid-Liquid Microextraction of Amphetamines from Biological Samples

Faezeh Khalilian; Mohammad Rezaee

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A mixed-hemimicelles (MHSPE) method coupled with dispersive liquid-liquid microextraction (DLLME) for the isolation and determination of amphetamines from biological samples is developed based on the use of sodium dodecyl sulfate (SDS)-coated Fe3O4 nanoparticles prior to the high performance liquid chromatography (HPLC-UV) analysis.

http://dx.doi.org/10.5935/0103-5053.20160101

Published online: April 5, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2114-2119

Decanoic Acid Reverse Micelle-Based Coacervates for Microextraction of Silver in Natural Waters Prior to Flame Atomic Absorption Spectrometry Determination

Marzieh Shokouhifar; Seyed Mohammad Hosseini; Mohammad Reza Jamali; Reyhaneh Rahnama

How to cite this article

 

Coacervates made up of reverse micelles of decanoic acid were proposed for the extraction of silver from natural water samples prior to its determination by flame atomic absorption spectrometry (FAAS).

http://dx.doi.org/10.5935/0103-5053.20160102

Published online: April 5, 2016

J. Braz. Chem. Soc. 2016, 27(11), 2120-2126

Simultaneous, Simple and Rapid Determination of Five Bioactive Free Anthraquinones in Radix et Rhizoma Rhei by Quantitative 1H NMR

Jian-Wei Dong; Le Cai; Yun-Shan Fang; Wei-He Duan; Zhen-Jie Li; Zhong-Tao Ding

How to cite this article

 

Five anthraquinones in Radix et Rhizoma Rhei could be quantified accurately using featured signals from 1H nuclear magnetic resonance (NMR), implying that quantitative 1H NMR represents a feasible alternative to high-performance liquid chromatography (HPLC)-based methods for quantitation of anthraquinones in Radix et Rhizoma Rhei.

http://dx.doi.org/10.5935/0103-5053.20160103

Published online: April 6, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2127-2140

Synthesis, in vitro Antifungal Activity and Molecular Modeling Studies of New Mannich Bases Derived from Lawsone

João F. Allochio Filho; Larissa L. Roldi; Maicon Delarmelina; Rodolfo G. Fiorot; Jessica T. Andrade; Álan A. Aleixo; Rafaella S. Carvalho; Marcelo G. F. Araújo; Jaqueline M. S. Ferreira; Alex G. Taranto; Wanderson Romão; Sandro J. Greco

How to cite this article

 

In this work, thirteen Mannich bases derived from lawsone were synthesized. Docking studies and evaluation of the antifungal activity were performed.

http://dx.doi.org/10.5935/0103-5053.20160104

Published online: April 6, 2016


J. Braz. Chem. Soc. 2016, 27(11), 2141-2148

HR-MAS NMR for Rapid Identification of Illicit Substances in Tablets and Blotter Papers Seized by Police Department

Luciano F. Souza; Tarcísio S. Vieira; Glaucia B. Alcantara; Luciano M. Lião

How to cite this article

 

1H nuclear magnetic resonance (NMR) high-resolution magic angle spinning (HR-MAS) technique represents an important time saver for identification of new synthetic illicit substances seized by police department.

http://dx.doi.org/10.5935/0103-5053.20160106

Published online: April 6, 2016


Short Report J. Braz. Chem. Soc. 2016, 27(11), 2149-2159

GC×GC-TOF/MS Analysis of Bio-Oils Obtained from Pyrolysis of Acuri and Baru Residues

Claudia Andrea L. Cardoso; Maria Elisabete Machado; Franksteffen S. Maia; Giberto Jose Arruda; Elina B. Caramão

How to cite this article

 

This study is the first report on the analysis of bio-oil from baru and acuri. The samples produced bio-oils with different compositions.

http://dx.doi.org/10.5935/0103-5053.20160081

Published online: March 18, 2016

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
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