Recent Papers - Machine Learning Special Issue
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Antimicrobial resistance is a global concern because is present in every country. Bacterial biofilm is associated with many persistent infections and increased resistance to antibiotics. Diguanylate cyclase enzymes (DGC) are an attractive target for antibiofilm drug intervention. Drug repurposing strategy resulted in DGC inhibitors discovery from therapeutics drugs using the integration of computational and biochemical assays. Details are presented in the Article Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases by Helton J. Wiggers, Édson Crusca, Éverton E. D. Silva, Juliana Cheleski, Naiara U. Torres and Marcos V. A. S. Navarro on page 297.
Helton J. Wiggers; Edson Crusca; Éverton E. D. Silva; Juliana Cheleski; Naiara U. Torres; Marcos V. A. S. Navarro
How to cite this articleAntimicrobial resistance is a global concern because is present in every country. Bacterial biofilm is associated with many persistent infections and increased resistance to antibiotics. Diguanylate cyclase enzymes (DGC) are an attractive target for antibiofilm drug intervention. Drug repurposing strategy resulted in DGC inhibitors discovery from therapeutics drugs using the integration of computational and biochemical assays. Details are presented in the Article Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases by Helton J. Wiggers, Édson Crusca, Éverton E. D. Silva, Juliana Cheleski, Naiara U. Torres and Marcos V. A. S. Navarro on page 297.
Alana L. C. Oliveira; Leonardo C. Ferreira; Marcos L. Dias; Rodrigo S. Bitzer; Marco A. C. Nascimento; Maria de Fátima V. Marques; Laura Crociani
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Bimetallic ZnII complexes with phenoxy-imine ligands were synthesized and used as initiators for lactide polymerization.
Anandhakumar Sukeri; Mauro Bertotti
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A nanostructured porous gold based electrocatalyst was fabricated via a facile electrochemical approach and an excellent activity with good stability for hydrogen evolution reaction was noticed.
Yanling Zhao; Xianmei Xie
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Based on thymine-Hg2+-thymine binding mode (T-Hg2+-T), a sensitive aptamer biosensor was constructed by utilizing functionalized Au@Ag core-shell nanoparticles as labels for detection of Hg2+.
Willian L. G. da Silva; Acacia A. Salomao; Patricia T. de Souza; Marina Ansolin; Matthieu Tubino
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The oil from the kernel of macauba presents high stability to oxidation, property that is transferred to its biodiesel, which also presents low cold filter plugging point. Such properties are inherited by its blends with biodiesels obtained from other vegetable oils.
Mena Ritota; Maria Mattera; Maria Gabriella Di Costanzo; Pamela Manzi
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Cheeses made with saffron are expected to provide an added value for consumers, due to saffron bioactive compounds. This UHPLC method seems to be useful to detect saffron crocins in dairy products.
Jean M. F. Custodio; Caua A. Moreira; Clodoaldo Valverde; Gilberto L. B. de Aquino; Basílio Baseia; Hamilton B. Napolitano
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The nature of crystal packing of an heterocyclic chalcone, investigated by Hirshfeld surfaces, and its potential nonlinear optical properties.
Aline A. N. de Souza; Viviane F. Xavier; Gleicekelly S. Coelho; Policarpo A. Sales Junior; Alvaro J. Romanha; Silvane M. F. Murta; Claudia M. Carneiro; Jason G. Taylor
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A series of novel substituted isoxazoles were prepared and tested for in vitro anti T. cruzi activity. The lead compound is equally as potent as reference drug benzonidazole.
Claudilene R. Silva; Rochel M. Lago; Helena S. Veloso; Patrícia S. O. Patricio
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The more efficient interaction of the fillers based on hydrophobic surface nanostructures with the hydrophobic UHMWPE chains leading to a much higher dispersion of the filler particles throughout the polymeric matrix.
Marcelo M. Alves; Aline L. Medina; Ane Martiele T. Pinto; Ana Clara N. Antunes; Pedro José Sanches Filho; Anderson S. Ribeiro; Mariana A. Vieira
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The concentration of Cu, Zn, Cr and Pb in different species of fish collected in the estuarine and limnic regions of the Sao Gonçalo channel in Pelotas City were determined.
Helton J. Wiggers; Edson Crusca; Éverton E. D. Silva; Juliana Cheleski; Naiara U. Torres; Marcos V. A. S. Navarro
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Virtual screening applied to FDA-approved drugs allowed the inhibitor discovery for enzymes diguanylate ciclases involved in the bacterial biofilm formation.
Mohammad Taghi Vardini; Leila Mardani
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Surface of the activated silica gel was grafted with the complex of MTD-APS. The custom made holes to the MTD remain on the surface of molecularly imprinted adsorbent.
Dorsan S. Moraes; Lucas C. R. Miranda; Rômulo S. Angélica; Geraldo N. Rocha Filho; José R. Zamian
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Schematic model of a 2:1 layer structure of the organofunctionalized materials present in this work, suggesting the superficial acid sites created.
Anderson J. Schwanke; Cristiano Favero; Rosana Balzer; Katia Bernardo-Gusmao; Sibele B. C. Pergher
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Polymerization reaction with a nickel-based catalyst supported on SBA-15 mesoporous materials.
Xiaosheng Tang; Ping Tang; Liangliang Liu
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Tetraethylenepentamine modified magnetic graphene oxide nanomaterial was prepared and it had a good adsorption ability to remove dyes in wastewater.
Larissa Sens; Aldo S. de Oliveira; Alessandra Mascarello; Inês M. C. Brighente; Rosendo A. Yunes; Ricardo J. Nunes
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The current study investigated the antioxidant activity, acetylcholinesterase inhibition and quantum studies of thiosemicarbazones.
Náira S. Campos; Marcone A. L. de Oliveira; Celly M. S. Izumi; Rafael A. de Sousa
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Lead content was evaluated in chicken viscera by GF AAS after solubilization with tetramethylammonium hydroxide (TMAH). Sample preparation was monitored by Raman spectroscopy and SEM-EDS.
Adriana R. Silva; José T. J. G de Lacerda; Bernadete Faria; Isabela W. da Cunha; Vitor P. de Andrade; Nilson A. Assunçao
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Mass spectrometry analysis as additional tool for description and differentiation of tumor physiopathology: a comparative proteomic study between pheomorphic sarcoma, metastasis and healthy tissues.
Emanueli do Nascimento da Silva; Mirla Cidade; Gabriel Heerdt; Rafael L. Ribessi; Nelson H. Morgon; Solange Cadore
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Selenate and selenite enrichment in the Veneza Roxa lettuce was carried out and the mineral composition was evaluated using ICP OES, PCA and molecular modeling. Selenate-biofortified lettuce showed a synergetic effect with S and Mo while selenite-biofortified lettuce showed a synergetic effect with Mn, P, Mg and Ca.
Marcus V. de Liz; Rubia M. de Lima; Bianca do Amaral; Belisa A. Marinho; Jessica T. Schneider; Noemi Nagata; Patricio Peralta-Zamora
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Photocatalytic degradation of estrogens by suspended and immobilized TiO2 were compared in aqueous and wastewater samples. The EE2 degradation products were monitored by GC-MS/MS.
William S. Martini; Brenda L. S. Porto; Marcone A. L. de Oliveira; Antonio C. Sant'Ana
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A fast evaluation of the degree of unsaturation and the presence of oxidized products in oil samples by Raman spectroscopy, through the identification of marker bands, assigned by supporting of GC-FID analyses of standard fatty acids.
Francisca D. S. Araújo; Marcela A. Botelho; José R. Trigo; Anita J. Marsaioli
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Chiral GC chromatogram of the peak discrimination of 2-methyl-6-undecylpiperidine trifluoroacetamide stereoisomers (synthetic standard mixture).
Jia-Xing Song; Xiang Fang; Tao Guo; Feng-Li Bei; Wen Ding; Xiao-Nan Zhang; Miao Yao; Hong-Jun Yu
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Thermal properties and kinetics of Al/α-MnO2 nanostructure thermite was reported in this work. According to DSC curves, the heat release and onset temperature were measured. Then the changes of activation energy on extent of conversion (α) for kinetics of Al/α-MnO2 thermite were obtained by using isoconversional method.
Gilvan E. S. Lima; Everton V. Nunes; Roberta C. Dantas; Carlos A. de Simone; Mario R. Meneghetti; Simoni M. P. Meneghetti
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Metal carboxylate complex modified with nitrogen ligands used as catalyst to oxidative polymerization of drying oils.
Cecilia Naspi; Agustín A. Costa; Alejandro Lucia; Paola G. Audino; Hector M. Masuh
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Fractionation of essential oils from Eucalyptus grandis x E. tereticornis, and its parental taxa, by HPLC followed by GC-MS analysis using two columns in series, allowed to determinate the enantiomeric excesses of selected monoterpenes. Significant differences were found in the enantiomeric ratios in monoterpene alcohols between the three essential oils.
Ellen V. Dalessandro; Josefredo R. Pliego Jr.
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Automated computational screening of 178 solvents for extraction of organic chemicals from aqueous phase.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access