JBCS

This review focuses on the importance of 1,2,4- and 1,3,4-oxadiazole cores in the design of new antiparasitic drugs. Here are highlighted the synthetic methodologies for their preparation as well as physicochemical differences between the isomers and their binding properties with biological receptors.

Recognition of the nanofibrous film chemosensor for Fe³⁺ by decrease of fluorescence.

Japanese grape seed oil (JGSO) is rich in alpha-linolenic acid (LNA) and was used to prepare supplemented diets for Nile tilapia. The replacement of soybean oil with JGSO in the prepared diets raises the nutritional lipid quality of the freshwater fish.

Principal component analysis with linear discriminant analysis (PCA-LDA) and quadratic discriminant analysis (PCA-QDA) were applied for discrimination between healthy control and cancer samples (ovarian and prostate cancer) based on mass spectra data sets.

A biosensor based on tyrosinase immobilized onto iron magnetic nanoparticles was successfully used for the simultaneous determination of two phenolic compounds after data analysis and chemometric treatment.

The combined effect of turbidity and chlorides on chemical oxygen demand have not been explored before this study and must be considered when the acid dichromate method is replaced by photoelectrochemical method.

Aerosol sampler installed at Tijuca sampling station, showing both EPA design PM₁₀ inlets, one for elemental analysis (left) and the other for carbon determination (right).

A new trinervitane diterpene isolated from termite soldiers (Nasutitermes macrocephalus) presented antimicrobial activities against S. aureus and C. albicans.

The mechanism of interaction between benzophenone derivatives and cruzain and Llacys1 (the protein expressed by cysteine protease gene isoform 1 of L. amazonensis) by homology modelling, docking and molecular dynamics simulation.

The decrease of the concentration of 5-Br salophen in presence of Zn²⁺ in organic phase leads to an optical sensor, in which the mechanism is described by ion-exchange.

The mean plasma concentration-time curves after an oral administration of Sedum sarmentosum Bunge extract are shown. The data conformed to a two-compartment, first-order pharmacokinetic model.

The photophysical behavior of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) is morphology-dependent in both solution and film form: the preparation method influences the exciton distribution.

Development of a novel mixed titanium, silver oxide nanofiber as a superior adsorbent for dyes removal in the wastewater treatment.

Chlorine present in crude oil is an important cause of problems related to corrosion and damage to equipment. This paper describes the development of a method for chlorine determination in crude oil samples through MgCl diatomic molecule by high-resolution continuum source molecular absorption spectrometry (HR-CS MAS).

A method based on ultrasound-assisted saponification (UAS) was proposed to determine phytosterols in passion fruit seed oil. The optimized UAS method extracted higher phytosterol concentrations and was about 3.3 times faster than the conventional saponification method.

Centrifugal ultrafiltration combined with liquid chromatography was used to screen alpha-amylase inhibitors from ten flavonoids mixture and the binding degrees ranged from 2.34 to 94.1%.

Blue-white tunable emission color in (Dy³⁺)-LaNbO₄ spherical particles synthesized by one-step spray pyrolysis process. The obtained CIE chromaticity coordinates fit the National Television Standard Committee (NTSC) standard values.

Simple and fast dispersive solid-phase extraction (d-SPE) method combined with syringe/filter to perform dyes analysis by high-performance liquid chromatography with ultraviolet-visible (HPLC-UV-Vis).

Chemical stability of hydroquinone (a) is compared to kojic (b). The hydroquinone was the most reactive. Its oxidation was inhibited more by N-acetylcysteine (d) than ascorbic acid (c).

Malondialdehyde (MDA) efficacy as a cancer biomarker in acute lymphoid leukemia (ALL) that affects young patients was experimentally evidenced. Biochemical parameter charts associating with MDA contents, determined by high performance liquid chromatography, applying chemometric tools, allowed correlating risk stratification and assist in the disease diagnosis.

Talaromyces fungi were isolated from Amazonian plants. From the antimicrobial extracts, 13 compounds were isolated and fully characterized by spectroscopic methods. Among the isolated compounds, polyketides, maleic anhydrides, and steroids were obtained, including two new compounds. The antifungal evaluation of the isolated compounds is described herein.

Fish oil omega-3 supplements are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) sources. However, fish oil is expensive raw material and its adulteration is common, especially with addition of edible oils with low cost, such as soybean oil. This study estimated the Brazilian reality regarding those supplements.

Herein we provide a simple and efficient approach for the synthesis of amino alcohols by using cardanol and glycerol building blocks with amines under catalyst-free and mild conditions. Some of these synthesized compounds exhibited significant antimicrobial activity against S. aureus and M. tuberculosis.

Solar cells with efficiencies of 4.9% were fabricated using a Cu₂ZnSnS₄ absorber layer synthesized following a novel chemical route based on the membrane assisted chemical bath deposition (CBD) technique.

An in-house validation of methods was used for determination of tetracyclines in chicken feather, muscle and liver tissues, through high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC MS/MS).