JBCS

The effects of cis-9, trans-11 conjugated linoleic acid (CLA) on the metabolic profile of MCF-7 and MDA-MB-231 breast cancer cells were evaluated using high-resolution magic angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy.

An efficient Knoevenagel condensation between aldehydes and lawsone was performed under new conditions showing good isolated yields in a short reaction time and simple conditions.

Substrate face controlled concerted oxidative rearrangement of N-acyltetrahydro-β-carbolines stereoselectively gives spiropyrrolidinyloxindoles.

Fourteen pyrazole compounds were synthesized and evaluated with regard to anticoagulant and antithrombotic activities. These derivatives were investigated through an integrated multiplex analysis virtual screening (IMA-VS) pipeline.

Determination of parabens in breast milk samples by dispersive liquid-liquid microextraction (DLLME) and ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS).

Analysis of cannabinoid standards by ultra performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight-mass spectrometry (UPLC-ESI-QTOF-MS) and UPLC-ESI-travelling wave ion mobility (TWIM)-MS.

Fifty-one compounds including PPCPs and pesticides were monitored from 2011 to 2014 in drinking and surface waters in Rio Grande do Sul State.

A series of triphenylamino (TPA)-chalcones and β-arylchalcones, displaying either D-π-D or D-π-A architecture, were synthesized and characterized. Photophysical and electrochemical properties of these compounds were evaluated.

Influence of copper and metallic alloys on the biodiesel oxidation reaction.

The conversion of 4,4'-dihydroxybenzophenone into a series of 1,2,3-triazolic derivatives resulted in the identification of bis(4-(1-(4-iodobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)benzophenone with significant elastase inhibitory activity (IC₅₀ = 16.6 ± 1.9 µM, inhibition constant (K_i) of 11.12 µM).

An in vitro evaluation of Ca, Cu, and Mg bioaccessibility in fresh and dried fruits was carried out, with results demonstrating that the dehydration process negatively affects bioaccessibility of Ca and Mg in dried fruits.

Novel 3,5-diiodophenethyl-benzamides as new lead compounds for the development of new anti-parasites treatment.

The quinazolinones showed a large range diastereotopic effect that was studied through nuclear magnetic resonance (NMR) and computational calculations.

Sonication extraction from leaves and fruits using response surface methodology and analysis of the extracts by gas chromatography-mass spectrometry (GC-MS) showing as major compounds: octanoic acid, vitamin E, phytol and hydroxymethylfurfural.

Optimization of sample preparation procedure in the extraction of cowpea proteins using the high-performance liquid chromatography (HPLC) technique as a comparative tool.

This work describes the first use of marine sponge Cliona varians as biocatalytic agents in the stereoselective reduction of α-keto esters and isatin.

Volatile organic compounds released by Heilipus lauri (Coleoptera: Curculionidae).

The synthesis and antimicrobial activity of thiazolidine-2,4-dione derivatives are described. The structures of the synthesized compounds were confirmed by infrared and nuclear magnetic resonance. All compounds were evaluated for their in vitro antibacterial activity. Density functional theory and principal component analysis were used to discriminate the compounds.

The polarization exponents (α^w) vary with the atomic number (Z) for a sequence of atoms in a row with the same valence structure. Thus, α^w can be obtained by interpolation.

Evaluation of efficiency of coconut charcoal and menthone-thiosemicarbazone as alternative solid phase extraction adsorbent for the determination of alkaloids in ayahuasca beverage.

The organoselenium compounds presented are prominent in medicinal chemistry; due to the increase of resistant fungi and bacteria, novel organoselenium compounds have been investigated as potent antimicrobials.

It was synthesized a new isatinspirooxazine derivative with an half maximal inhibitory concentration (IC₅₀) = 0.34 µM, more potent than the reference drug, doxorubicin (IC₅₀ = 1.88 µM), in breast cancer line MDA-MB231.