JBCS

Chemical and biological evaluation of tenofovir paves the way for clinical and pre-clinical investigations.

Synthesis of fatty acid amides from the oil of Bertholletia excelsa, using Amano lipase from Pseudomonas fluorescens, demonstrated anti-inflammatory activity.

Antimicrobial nanocomposites with 1, 3, and 5 wt.% of nanostructured ZnO in polyethylene were obtained using in situ polymerization.

The picture shows a flowchart of the method: beginning with the broad literature search made for bisphenol A (BPA) determination in water samples, followed by the extraction and back-extraction steps performed in this study.

The formation of an inclusion complex (IC) between benzbromarone and β-cyclodextrin has been studied through experiments (differential scanning calorimetry (DSC) analysis and X-ray diffraction), and theoretical calculations (ONIOM(TD-B97D:PM6)).

Aluminum phosphate (AlP) catalysts prepared by a simple replacement reaction method exhibited excellent catalytic performance for glycerol dehydration. AlP-500 showed highest acrolein selectivity of 66% at 98% glycerol conversion. The acidity of AlP-T played an important role in the glycerol dehydration reaction.

This study presents the synthesis and evaluation of quinoline inhibitory activity against cathepsin K (CatK). Molecular docking studies provided important information on the interaction of the inhibitor with the enzyme.

Nanoencapsulated carvacryl acetate (nCVA) with chitosan, sodium tripolyphosphate (TPP) and chichá gum (CG) in bilayer.

Soil layers from Amazonian dark earth and the surrounding soil were characterized by organic and inorganic contents.

A new designed fluorescent chemosensor TYMN ((E)-1-((thiazol-2-ylimino)methyl)naphthalen-2-ol) for highly sensitive and selective tracing of trace amount of Zn²⁺ ions in some real samples. The probe TYMN may have application as a fluorophore to detect the Zn²⁺ in living cells.

ZnO catalyst produced by the sol-gel protein route to promote the degradation of methylene blue dye and ibuprofen drug when irradiated with UV light.

The biodegradation of the pyrethroid pesticide esfenvalerate by a bacterial consortium (90% biodegradation) and the major obtained metabolites.

The biodiesel degradation process was realized in the Rancimat equipment and analyzed by ¹H nuclear magnetic resonance (NMR).

Piperine was used as a precursor in the synthesis of twelve new diester derivatives. The alkyl 2-chloroacetates were coupled to the piperic group, and their potential as new drugs was evaluated through in silico study and evaluation of in vitro antimicrobial activity.

Chemical characterization and in vitro cytotoxic potential of three Copaifera oleoresin metabolites against tumoral cell lines.

Use of nuclear magnetic resonance (NMR)-chemometric models to detect and estimate changes in the anti-knock indexes of Brazilian premium and common gasolines.

All phenothiazine dyes concentrate, predominantly, in the polymer enriched phase, due to the dye-poly(ethylene oxide) (PEO) attractive interactions that occur mainly via benzene condensed ring present in the structures of dyes, which made the partitioning process enthalpically driven.

Bio-oil was used to dispersed Fe³⁺, which upon thermal treatment (400-600 °C) and sulfonation produced a magnetic acid catalyst for esterification reactions.

The pharmochemicals 1,3-dihydroxyacetone (1), 1,3-dichloroacetone (6), 1,3-dibromoacetone (7) and 1,3-diiodoacetone (8) were efficiently synthesized from glycerol in good yields using reagents supported on polymer resins or alumina, some of them under solvent free conditions.

The experimental and theoretical results suggested that imiquimod was embedded inside β-cyclodextrin cavity with the isobutyl moiety and the imidazole ring oriented to the inner edge of the macromolecule.

A Pb^II-based energetic combustion catalyst shows excellent catalytic performances on the thermal decomposition of ammonium perchlorate (AP) and cyclotrimethylenetrinitramine (RDX).

A new isoflavone diglycoside was isolated from Clitoria guianensis roots together with seven known compounds.