JBCS

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vol. 31, No. 12, 2020, p. 2439-2657

 

The hydnocarpic acid isolated from Carpotroche brasiliensis seed oil was used to obtain a series of derivatives containing1,2,3-triazole ring. The derivative (R)-(1-(pyridin-2-ylmethyl)-1H-1,2,3-triazol-4-yl)methyl-11-(cyclopent-2-en-1-yl) undecanoate exhibited promising antiproliferative activity on the lung adenocarcinoma cell line by inhibiting cell cycle progression at G1 phase. Details are presented in the Article Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity by Liseth S. Osorio, Marisa Ionta, Antonio J. Demuner, Bianca L. de Sousa, Guilherme O. Ferraz, Eduardo V. V. Varejão, Guilherme A. F. Silva, Eduardo J. Pilau, Evandro Silva and Marcelo H. dos Santos on page 2500.


Cover Article
J. Braz. Chem. Soc. 2020, 31(12), 2500-2510

Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity

Liseth S. Osorio; Marisa Ionta; Antonio J. Demuner ; Bianca L. de Sousa ; Guilherme O. Ferraz; Eduardo V. V. Varejão; Guilherme A. Ferreira-Silva; Eduardo J. Pilau ; Evandro Silva ; Marcelo H. dos Santos

How to cite this article

The hydnocarpic acid isolated from Carpotroche brasiliensis seed oil was used to obtain a series of derivatives containing1,2,3-triazole ring. The derivative (R)-(1-(pyridin-2-ylmethyl)-1H-1,2,3-triazol-4-yl)methyl-11-(cyclopent-2-en-1-yl) undecanoate exhibited promising antiproliferative activity on the lung adenocarcinoma cell line by inhibiting cell cycle progression at G1 phase. Details are presented in the Article Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity by Liseth S. Osorio, Marisa Ionta, Antonio J. Demuner, Bianca L. de Sousa, Guilherme O. Ferraz, Eduardo V. V. Varejão, Guilherme A. F. Silva, Eduardo J. Pilau, Evandro Silva and Marcelo H. dos Santos on page 2500.

https://dx.doi.org/10.21577/0103-5053.20200125

Published online: June 23, 2020
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Review J. Braz. Chem. Soc. 2020, 31(12), 2439-2451

Calibration Strategies Applied to Laser-Induced Breakdown Spectroscopy: A Critical Review of Advances and Challenges

Vinicius C. Costa; Diego V. Babos; Jeyne P. Castro; Daniel F. Andrade; Raimundo R. Gamela; Raquel C. Machado ; Marco A. Sperança; Alisson S. Araújo; José A. Garcia; Edenir R. Pereira-Filho

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Several calibration strategies have been reported in the literature over the last few years to improve quantitative analysis using laser-induced breakdown spectroscopy (LIBS).

https://dx.doi.org/10.21577/0103-5053.20200175

Published online: August 28, 2020

 

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Articles J. Braz. Chem. Soc. 2020, 31(12), 2452-2461

Application of Nickel Ferrite Nanoparticles in Adsorption of Amoxicillin Antibiotic

Patricia M. A. Caetano ; Nathália M. Simões; Paula S. Pinto; Luis E. Fernandez‑Outon; Adriana S. Albuquerque; Waldemar A. A. Macedo; José D. Ardisson

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The adsorption and subsequent removal of amoxicillin from aqueous solution was investigated using nickel ferrite (NiFe2O4) nanoparticles.

https://dx.doi.org/10.21577/0103-5053.20200120

Published online: June 19, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2462-2469

A Straightforward Synthesis of Enantiopure (1S,2R)-Ephenamine

Arthur C. C. Velho; José E. D. Martins

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(1S,2R)-Ephenamine was synthesized starting from commercially available chiral amino acid through straightforward procedures on a six-step methodology.

https://dx.doi.org/10.21577/0103-5053.20200121

Published online: June 19, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2470-2478

X-ray Scattering and Chemometrics as Tools to Assist in the Identification of Gunshot Residues by Wavelength Dispersive X-ray Fluorescence Spectrometry

Fernanda B. Madeira; Victor G. P. Saide; Martha T. P. O. Castro; Cristina M. Barra; Sheisi F. L. S. Rocha; Vanessa G. K. Almeida; André V. S. Canuto; Gustavo G. Shimamoto; Matthieu Tubino ; José G. Rocha Jr.

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Gunshot residue (GSR) was analyzed with wavelength dispersion X-ray fluorescence spectrometry (WDXRF), discriminated according firearm/cartridge type by principal component analysis and classified as GSR and non-GSR by k-nearest neighbors (k-NN) method.

https://dx.doi.org/10.21577/0103-5053.20200122

Published online: June 19, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2479-2490

Determination of Total Antioxidant Capacity Using Thiamine as a Natural Fluorescent Probe

Woodland S. Oliveira; Josué C. C. Santos

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The fluorimetric method proved to be simple, rapid, and sensitive for determination of the total antioxidant capacity of drinks based on thiamine oxidation inhibition.

https://dx.doi.org/10.21577/0103-5053.20200123

Published online: June 22, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2491-2499

Optimization of Methodology for Determination of Inorganic Chromium Species in Sewage Sludge Samples by HPLC-ICP-MS/MS

Érica S. Barbosa; Ane P. Cacique; Gevany P. de Pinho; Flaviano O. Silvério

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Representation of a valid methodology for determining CrIII and CrVI in sewage sludge samples by high performance liquid chromatography, inductively coupled plasma tandem mass spectrometry (HPLC-ICP-MS/MS).

https://dx.doi.org/10.21577/0103-5053.20200124

Published online: June 23, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2500-2510

Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity

Liseth S. Osorio; Marisa Ionta; Antonio J. Demuner ; Bianca L. de Sousa ; Guilherme O. Ferraz; Eduardo V. V. Varejão; Guilherme A. Ferreira-Silva; Eduardo J. Pilau ; Evandro Silva ; Marcelo H. dos Santos

How to cite this article

 

Conversion of hydnocarpic acid into a triazole compound 8 with antiproliferative activity (concentration able to inhibit 50% growth (IC50) = 63.96 ± 3.98 µM) against lung adenocarcinoma (A549).

https://dx.doi.org/10.21577/0103-5053.20200125

Published online: June 23, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2511-2517

Evaluation of Dog Food Authenticity through Lipid Profile Using GC-FID and ESI‑MS

Roberta da Silveira ; Patrícia D. S. dos Santos; Jessica S. Pizzo ; Nayane Mattos; Matheus C. de Castro; Oscar O. Santos ; Jesuí V. Visentainer

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Regarding the adulteration increase, it is essential to assess the guarantee levels declared by the manufacturers in the packaging of its products using analytical techniques.

https://dx.doi.org/10.21577/0103-5053.20200126

Published online: June 23, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2518-2530

Multiresidue Determination of Endocrine Disrupting Compounds in Sewage Treatment Plants (SPE-HPLC-DAD)

Carla B. Vidal ; Pablo G. A. Barbosa; Germana P. Pessoa; Patrícia C. Buarque; José G. S. Nascimento; Antônio L. Farias Filho; Mário S. Paz; André B. dos Santos; Rivelino M. Cavalcante; Ronaldo F. Nascimento

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Solid phase extraction followed by high-performance liquid chromatography with diode array detection (SPE-HPLC-DAD) method was validated and applied to endocrine disruptors environmental monitoring detection; hormones, pharmaceuticals and plastic compounds were found in high concentration in sewage treatment plants in Ceará, Brazil; biological treatments showed some efficiency in removal of endocrine disruptors compounds, although a post-treatment step is necessary.

https://dx.doi.org/10.21577/0103-5053.20200127

Published online: June 25, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2531-2543

NMR in Analysis of the Nutritional Value of Lipids from Muscles and Livers of Wild Amazonian Fishes with Different Eating Habits Over Seasonal Variation

Banny S. B. Correia ; Gilberto G. D. Ortin; Natalia C. Mor; Maiara S. Santos; Raquel S. Torrinhas; Adalberto L. Val; Ljubica Tasic

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The evaluation of environmental effects on the lipids of Amazonian wild fishes is presented. Focus was given on seasonal dynamics of the river, eating habits, and tissue.

https://dx.doi.org/10.21577/0103-5053.20200130

Published online: June 29, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2544-2552

Identification of Flavonoids as Inhibitors of Plasmodium falciparum Enoyl-ACP Reductase by Hierarchical Virtual Screening

Dayse A. A. Silva; Diego M. da Costa; Larissa M. Oliveira; Hugo N. Brandão; Clayton Q. Alves; Aníbal F. Santos Jr. ; Manoelito C. dos Santos Jr.

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Identification of flavonoids as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein (ACP) reductase was evaluated by hierarchical virtual screening and intermolecular interactions contributed to the molecular recognition process.

https://dx.doi.org/10.21577/0103-5053.20200132

Published online: June 30, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2553-2560

Determining Mercury in Sediment Samples by Extraction Using a Novel-Chelating Reagent Dithiothreitol (DTT) Followed by Cold Vapor Atomic Fluorescence Spectrometry (CV-AFS)

Robson M. de Jesus; Geovani C. Brandão; Walter N. L. dos Santos; Leila O. dos Santos; Jailson B. de Andrade

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Hg is quantitatively extracted from the sediment using a new chelating reagent dithiothreitol.

https://dx.doi.org/10.21577/0103-5053.20200133

Published online: July 1, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2561-2568

Development of a First-Order Derivative UV Spectrophotometric Method for the Assay and Solubility Evaluation of Lamotrigine and Nicotinamide Cocrystals

Isabela F. B. Biscaia; Vitor Todeschini; Rafaela Z. C. de Meira; Camila Nogueira; Larissa S. Bernardi; Paulo R. de Oliveira

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First-order derivative spectrum of lamotrigine and nicotinamide allows the simultaneous assay of the drugs in cocrystals.

https://dx.doi.org/10.21577/0103-5053.20200134

Published online: July 3, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2569-2582

Synthesis and Antioxidant and Antimicrobial Properties of β-Hydroxy Sulfides, Sulfoxides, and Sulfones Derived from Cardanol and Glycerol Derivatives

Suély Copini; Ana C. Micheletti ; Dênis P. de Lima ; Roberto S. Gomes ; Alisson Meza; Adilson Beatriz

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Twenty-eight novel organosulfur compounds were synthesized from a molecular combination of cardanol and glycerol derivatives, with excellent yields and employing more environmentally friendly processes.

https://dx.doi.org/10.21577/0103-5053.20200136

Published online: July 6, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2583-2589

Method for Cleaning Back-Produced Water from Polymer Flooding Operations to Determine Polymer Molar Mass Using Size-Exclusion Chromatography

Suzanny P. Carvalho; Rocio M. M. Dip; Elizabete F. Lucas

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Steps of the cleaning treatment for produced water aiming the analyses of the polymer by size-exclusion chromatography.

https://dx.doi.org/10.21577/0103-5053.20200138

Published online: July 7, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2590-2602

Synthesis, in silico Study and Antimicrobial Activity of New Piperine Derivatives Containing Substituted
δ-Esters

Emmely O. Trindade; Thalisson F. Dutra; Maria C. R. Brandão; Hermes Diniz Neto ; Edeltrudes O. Lima; Bruno F. Lira; Petrônio F. de Athayde-Filho; José M. Barbosa-Filho

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Fifteen new piperine derivatives were planned and synthesized. The new compounds were obtained through the substitution reaction between δ-chloro-esters and potassium piperate, and were evaluated through in silico study and in vitro for antimicrobial activity.

https://dx.doi.org/10.21577/0103-5053.20200140

Published online: July 9, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2603-2610

Green Extraction Optimization of Bioactive Compounds from Rosemary (Rosmarinus officinalis L.) Using Response Surface Methodology

Tiago A. M. Lopes; Antonio C. Godoy; Nayane B. M. Sinosaki; Patrícia D. S. Santos; Lucas U. R. Chiavelli; Roberta Silveira ; Bruno H. Figueiredo; Jesuí V. Visentainer ; Oscar O. Santos

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The extraction of bioactive compounds present in rosemary (R. officinalis L.) using water as solvent comprises the context of green chemistry, as non-toxic solvent, high availability and low cost. It is necessary to optimize the extraction methods in order to obtain a high concentration of antioxidant compounds.

https://dx.doi.org/10.21577/0103-5053.20200142

Published online: July 9, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2611-2619

Activated Complex Approach to Describe Bovine Serum Albumin-Azure A and Bovine Serum Albumin-Azure B Intermolecular Interactions

Hauster M. C. de Paula; Yara L. Coelho; Alan S. B. de Castro; Jaqueline P. Rezende; Ana C. S. Pires; Luis H. M. da Silva

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Bovine serum albumin (BSA) interacts with azure B (AZB) or azure A (AZA) through a transition complex. The formation of activated and thermodynamically stable complexes was entropy-driven at 25 °C.

https://dx.doi.org/10.21577/0103-5053.20200143

Published online: July 14, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2620-2627

An Electrochemiluminescence Biosensor for the Determination of Mercury Ion via Dual-Amplification Strategy

Xuemei Fan ; Shumin Wang ; Zhejian Li ; Yimeng Wang; Xinhui Fan; Lingmin Yu

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A sensitive electrochemiluminescence biosensing platform for the detection of Hg2+ was designed via dual-amplification strategy.

https://dx.doi.org/10.21577/0103-5053.20200144

Published online: July 17, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2628-2637

Multifunctionality of βCD/Ofloxacin and HPβCD/Ofloxacin Complexes: Improvement of the Antimicrobial Activity and Apoptosis Induction on Lung Adenocarcinoma A549 Cells

Bolivar R. Amaro; Caio C. S. Alves; Gabriella F. Ferreira; Paloma E. Carvalho; Jeferson G. da Silva; Cleonice A. Souza; Oswaldo Cardoso Jr.; Alessandra P. Carli; Fabiana S. Machado; Ângelo M. L. Denadai; Sandra B. R. Castro

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Inclusion complexes of β-cyclodextrin/ofloxacin (βCD/OFLOX) and hydroxypropyl-β-cyclodextrin/ofloxacin (HPβCD/OFLOX) enhance the solubility and bioavailability with increased antitumor and apoptosis induction activity.

https://dx.doi.org/10.21577/0103-5053.20200145

Published online: July 17, 2020

 

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Short Report J. Braz. Chem. Soc. 2020, 31(12), 2638-2643

Identification of Potential Inhibitors of Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Main Protease from Non-Natural and Natural Sources: A Molecular Docking Study

Osvaldo A. Santos-Filho

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Corilagin docked into the binding site of coronavirus 2 (CoV-2) main protease.

https://dx.doi.org/10.21577/0103-5053.20200139

Published online: July 7, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2644-2650

Bergenin of Peltophorum dubium (Fabaceae) Roots and Its Bioactive Semi-Synthetic Derivatives

Oscar C. da Silva Neto; Marla T. F. Teodoro; Bruna O. do Nascimento; Klauber V. Cardoso ; Eliane O. Silva ; Jorge M. David ; Juceni P. David

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Bergenin of Peltophorum dubium roots and its alkyl alcohol derivatives displayed moderate and good inhibitory effects on
Artemia salina, Staphylococcus aureus, and acetylcholinesterase (AChE).

https://dx.doi.org/10.21577/0103-5053.20200141

Published online: July 9, 2020

 

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Additions and Corrections J. Braz. Chem. Soc. 2020, 31(12), 2651-2652


 

https://dx.doi.org/10.21577/0103-5053.20200198

Published online: October 28, 2020

 

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J. Braz. Chem. Soc. 2020, 31(12), 2653-2657

Reviewer List 2020


 

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Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
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University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil

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