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The use of lipases in organic synthesis is a useful tool to obtain high value chiral compounds. However, the enzymatic resolution allows only 50% of maximum yield. To circumvent this issue the discovery of new racemization agents is desirable. In this unprecedented work, we observed that niobium phosphate could racemize chiral 1-phenylethanol. And this new reactivity of niobium led to the development of a DKR (dynamic kinetic resolution) protocol. Details are presented in the Article Lipase-Mediated Dynamic Kinetic Resolution of 1-Phenylethanol Using Niobium Salts as Racemization Agents by Vanessa M. Higa, Willian S. Rocha, Mirela Inês de Sairre and Álvaro T. Omori on page 1956.
Vanessa M. Higa ; Willian S. Rocha; Mirela Inês de Sairre; Álvaro T. Omori
How to cite this articleThe use of lipases in organic synthesis is a useful tool to obtain high value chiral compounds. However, the enzymatic resolution allows only 50% of maximum yield. To circumvent this issue the discovery of new racemization agents is desirable. In this unprecedented work, we observed that niobium phosphate could racemize chiral 1-phenylethanol. And this new reactivity of niobium led to the development of a DKR (dynamic kinetic resolution) protocol. Details are presented in the Article Lipase-Mediated Dynamic Kinetic Resolution of 1-Phenylethanol Using Niobium Salts as Racemization Agents by Vanessa M. Higa, Willian S. Rocha, Mirela Inês de Sairre and Álvaro T. Omori on page 1956.
Ottávio R. Carmignano; Sara S. Vieira ; Ana Paula C. Teixeira; Fernando S. Lameiras; Paulo Roberto G. Brandão; Rochel M. Lago
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Iron ore tailings (IOT) are mainly composed of iron oxides, silica, and other minerals such as kaolinite. The IOT can be used for different applications related to the civil construction and a variety of technological applications.
Dyovani Coelho; Giuliana M. Luiz; Sergio A. S. Machado
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Roughness factors increase with platinization time, but cyclic voltammetry cannot detect it.
Francisco Alessandro M. Rodrigues ; Priscylla S. Giffony; Sarah B. F. dos Santos ; Jhonyson A. C. Guedes ; Maria Elenir N. P. Ribeiro ; Tamara G. de Araújo; Larissa M. R. da Silva; Guilherme J. Zocolo ; Nágila M. P. S. Ricardo
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Chemical profile, the antioxidant capacity and in vitro photoprotective action of phenolic extracts of Spondias purpurea L. in sunscreen formulations.
Renan O. Gonçalves ; Iolanda F. de Farias; Maria Francilene S. Silva; Cláudia Ó. Pessoa; Guilherme J. Zocolo ; Davila Zampieri; Telma Leda G. de Lemos; Francisco Jose Q. Monte
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Synthesis and characterization of esters derived from cinnamic acid through Steglich reaction and evaluated in tumor cells.
Jéssica R. Nogueira; Flávia A. Verza; Felipe Nishimura; Umashankar Das; Ícaro P. Caruso; Ana L. Fachin; Jonathan R. Dimmock; Mozart Marins
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Molecular docking studies reveals that curcumin analogues have the potential to inhibit severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike protein interaction with host receptor.
Vanessa M. Higa ; Willian S. Rocha; Mirela Inês de Sairre; Álvaro T. Omori
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Dynamic kinetic resolution of 1-phenylethanol by combination of niobium salts and lipase.
Shuangshuang Wang ; Yanzhen Yin; Jian Gao; Xingtang Liang; Haixin Shi
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The four macrocyclic molecules were built and used for studying the effects of the solvents on the macrocyclic structures.
Eduardo A. Ribeiro; Vanderlei G. Machado
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Three phenolic imines were used as chromogenic chemosensors to detect alkylamines in water. The system allows the detection of vapors of alkylamines and quantification of lidocaine in water.
Tatiane R. Amparo; Francine M. Djeujo; Débora S. da Silva; Janaina B. Seibert; Ivanildes V. Rodrigues; Orlando D. H. Santos; Geraldo C. Brandão; Paula M. A. Vieira; Guglielmina Froldi ; Gustavo H. B. de Souza
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Protium spruceanum branches: phytochemistry, anti-α-glucosidase activity, and cytoprotection against oxidative stress.
Pedro M. de Sousa Jr.; Simone F. P. Pereira; Ronaldo M. Rocha; Mateus H. D. Alves; Luciana S. Pinheiro; Daniel P. Nogueira; Orivan M. M. Teixeira; Auriane C. S. Gonçalves
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The graph is intended to illustrate how beneficial it is for environmental research to integrate individually recognized statistical and computer simulation models in the production of realistic scenarios and decision-making regarding the mitigation of environmental disasters.
Bruno H. F. Saqueti; Eloize S. Alves; Matheus C. Castro ; Patrícia D. S. dos Santos; Nayane B. M. Sinosaki; Carlos E. R. Senes ; Jesuí V. Visentainer ; Oscar O. Santos
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The antioxidant activity, bioactive compounds, and storage stability of acerola pulp were evaluated using three different conservation methods: frozen (FAP), freeze-drying (LAP), and microencapsulated and freeze-drying (MLAP).
Palmira L. dos Santos Neta; Carla F. Fávaro ; Sarah O. Macedo; José Inácio L. Moura; Jan E. Bello; Rândilla R. C. Santos;
Paulo H. G. Zarbin
Amerrhinus ynca produces a male-specific compound, and by using chemical analysis of volatile extracts the molecule was identified as octadecanal. Indoor bioassays employing a synthetic sample suggested the molecule as being the aggregation pheromone of species.
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
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