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vol. 33, No. 3, 2022, p. 205-302

 

A efficient tandem synthesis of furanaphthoquinones via enamines provides compounds with activity against the epimastigote form of Trypanosoma cruzi, the parasite that causes Chagas disease. Details are presented in the Article Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi by Mariana F. C. Cardoso, Luana S. M. Forezi, Acácio S. de Souza, Ana F. M. Faria, Raissa M. S. Galvão, Murilo L. Bello, Fernando C. da Silva, Robson X. Faria and Vitor F. Ferreira on page 238.


Cover Article
J. Braz. Chem. Soc. 2022, 33(3), 238-250

Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi

Mariana F. C. Cardoso ; Luana S. M. Forezi ; Acácio S. de Souza ; Ana F. M. Faria; Raissa M. S. Galvão; Murilo L. Bello; Fernando C. da Silva ; Robson X. Faria ; Vitor F. Ferreira

How to cite this article

A efficient tandem synthesis of furanaphthoquinones via enamines provides compounds with activity against the epimastigote form of Trypanosoma cruzi, the parasite that causes Chagas disease. Details are presented in the Article Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi by Mariana F. C. Cardoso, Luana S. M. Forezi, Acácio S. de Souza, Ana F. M. Faria, Raissa M. S. Galvão, Murilo L. Bello, Fernando C. da Silva, Robson X. Faria and Vitor F. Ferreira on page 238.

https://dx.doi.org/10.21577/0103-5053.20210142

Published online: October 18, 2021
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Articles J. Braz. Chem. Soc. 2022, 33(3), 205-216

Graphite-Polyurethane Composite Electrode Modified with Molecularly Imprinted Polymer for Determination of Diclofenac

Abigail V. Pereira; Priscila Cervini ; Victor A. G. Rivera; Éder T. G. Cavalheiro

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Schematic figure of molecularly imprinted polymer (MIP) synthesis using diclofenac (DCF) as template and the modification of a graphite-polyurethane composite electrode (GPUE) with MIP-DCF for the voltammetric determination of diclofenac. Voltammetric response of GPUE-2.5-MIP-DCF in comparison to glassy carbon (GC) and unmodified GPUE.

https://dx.doi.org/10.21577/0103-5053.20210138

Published online: October 6, 2021

 

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J. Braz. Chem. Soc. 2022, 33(3), 217-226

Extracts of the Native Brazilian Tree Garcinia gardneriana Inhibit Urediniospore Germination of Coffee Leaf Rust Fungus

Ueveton P. da Silva; Bruno W. Ferreira; Bianca L. de Sousa ; Gabriela M. Furlani; Robert W. Barreto; Ana Paula Agrizzi ; João Paulo V. Leite ; Marcelo H. dos Santos ; Eduardo V. V. Varejão

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Extract from the plant Garcinia gardneriana inhibited germination of Hemileia vastatrix at a concentration with no phytotoxic activity.

https://dx.doi.org/10.21577/0103-5053.20210139

Published online: October 6, 2021

 

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Total access: 941


J. Braz. Chem. Soc. 2022, 33(3), 227-237

Synthesis and Biological Evaluation of Novel Betulin Derivatives with Aromatic Hydrazone Side Chain as Potential Anticancer Agents

Jiafeng Wang; Jiale Wu; Yinglong Han; Jie Zhang; Yu Lin; Haijun Wang; Jing Wang; Ming Bu

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Fifteen betulin derivatives 7a-7o were synthesized. Compound 7l displayed the most potent antitumor activity, which also could induce apoptosis of MCF-7 cells.

https://dx.doi.org/10.21577/0103-5053.20210140

Published online: October 13, 2021

 

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J. Braz. Chem. Soc. 2022, 33(3), 238-250

Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi

Mariana F. C. Cardoso ; Luana S. M. Forezi ; Acácio S. de Souza ; Ana F. M. Faria; Raissa M. S. Galvão; Murilo L. Bello; Fernando C. da Silva ; Robson X. Faria ; Vitor F. Ferreira

How to cite this article

 

This strategy provides an efficient and general method for synthesizing furanaphthoquinones with activity against the epimastigote form of Trypanosoma cruzi, the parasite that causes Chagas disease.

https://dx.doi.org/10.21577/0103-5053.20210142

Published online: October 18, 2021

 

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Total access: 1396


J. Braz. Chem. Soc. 2022, 33(3), 251-259

Rapid Recognizing the Producing Area of a Tobacco Leaf Using Near-Infrared Technology and a Multi-Layer Extreme Learning Machine Algorithm

Ruidong Li; Wenyong Huang; Guanlan Shang; Xiaobing Zhang; Xin Wang; Jianguo Liu; Yong Wang; Junfeng Qiao; Xing Fan; Kai Wu; Wenhua Zi

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A near-infrared (NIR) spectroscopy device is a useful tool for rapid recognizing the producing areas of Yunnan tobacco leaves.

https://dx.doi.org/10.21577/0103-5053.20210143

Published online: October 21, 2021

 

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J. Braz. Chem. Soc. 2022, 33(3), 260-267

Response Factor in GC-FID Methyl Ester Analysis in Several Biodiesels: A Comparative Study of the
EN 14103:2011 and ABNT 15764:2015 Methods versus a Proposed GC-FID Procedure for Individual Ester Determination

Willian L. G. da Silva; Arnaldo G. Oliveira Jr.; Matthieu Tubino

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A gas chromatography method with a flame ionization detector enabled by relative response factor was developed to determine the individual and the total content of esters in biodiesel.

https://dx.doi.org/10.21577/0103-5053.20210144

Published online: October 26, 2021

 

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J. Braz. Chem. Soc. 2022, 33(3), 268-273

Structural Characteristics of Lignite Char from Different Pyrolysis Reactors and the Influence on Their Gasification Reactivity

Ying Zhang ; Haitang Wang; Xiaoqin Wang

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The structural features of lignite char obtained from different reactors were characterized and the influence on their gasification reactivity under different atmospheres was investigated.

https://dx.doi.org/10.21577/0103-5053.20210145

Published online: October 27, 2021

 

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J. Braz. Chem. Soc. 2022, 33(3), 274-280

How Much do the Environmental Conditions Interfere with the Essential Oils of Eugenia spp. L. (Myrtaceae)?

Raisa M. Silveira ; Ana F. U. Carvalho; Mariana O. Bünger; Manuella M. Gomes; Itayguara R. da Costa

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Chemometric analyzes were performed to determine the influence of environmental conditions on essential oils from Eugenia species. Interspecific phytochemical patterns and statistical regression models were estimated.

https://dx.doi.org/10.21577/0103-5053.20210146

Published online: October 28, 2021

 

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Total access: 725


J. Braz. Chem. Soc. 2022, 33(3), 281-290

Use of Direct Aqueous Injection and Solid Phase Extraction Coupled with Hydrophilic Interaction Chromatography to Analyze Haloacetic Acids in Drinking Water Samples

Andrea C. Begambre Berrio ; Sergiane C. Barbosa ; Jean L. O. Arias ; Lucas C. Marcolin; Ednei G. Primel

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The present study reports the use of a high-performance liquid chromatography (HPLC) Luna column in the hydrophilic interaction chromatography (HILIC) mode to determine six brominated and chlorinated haloacetic acids (HAAs) in drinking water samples by sample preparation techniques, such as direct aqueous injection (DAI) and solid phase extraction (SPE), based on the principles of green analytical chemistry.

https://dx.doi.org/10.21577/0103-5053.20210147

Published online: November 3, 2021

 

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Total access: 819


J. Braz. Chem. Soc. 2022, 33(3), 291-302

A New Synthetic Route and Comprehensive Topological Study of a Benzimidazole Derivative

Vitor S. Duarte ; Raquel F. Naves; Adailton J. Bortoluzzi; Eduardo C. M. Faria; Aline M. da Silva; Guilherme R. Oliveira; Christian G. Alonso ; Hamilton B. Napolitano

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Synthesis study involving graphite oxide and supramolecular arrangement of a new benzimidazole derivative.

https://dx.doi.org/10.21577/0103-5053.20210149

Published online: November 10, 2021

 

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Total access: 864

Online version ISSN 1678-4790 Printed version ISSN 0103-5053
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