Recent Papers - Machine Learning Special Issue
Reviews/Accounts - last 5 years
Medicinal Chemistry Collection 2022-2023
Papers from 2023
Synthesis and Evaluation of Antibacterial Activity of 1,2,3-Triazole and Ether Derivatives of Paeonol
Laura Patricia R. Figueroa; Nayara A. dos Santos; Pedro Henrique O. Santiago; Wanderson Romão
; Valdemar Lacerda Junior ; Javier Ellena ; Ana Camila Micheletti; Warley S. Borges
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect
Adrianne B. Ferreira ; Cleber G. Novaes ; Hion O. de Jesus; Julita Maria P. Borges; Florisvaldo S. Ramos; Anderson J. Pereira; Djalma M. de Oliveira; Rosane M. Aguiar
Indoquinoline Alkaloids from Sida rhombifolia (L.) (Malvaceae) and Antimicrobial Evaluation of Cryptolepinone Derivatives
Micaelly S. Oliveira; Otemberg S. Chaves; Laísa V. Cordeiro; Ayala N. P. Gomes; Diégina A. Fernandes; Yanna C. F. Teles; Tania M. S. da Silva ; Kristerson R. L. Freire; Edeltrudes O. Lima; Maria de Fátima Agra; Maria de Fátima V. de Souza
Amazonian Fruit Mari-Mari (Cassia leiandra Benth.): Identification of Flavonoids and Antioxidant, Antimicrobial and Antiproliferative Properties
Mayane P. de Souza; Ingrity Suelen C. Sá; Flávio Augusto de Freitas ; Afonso D. L. de Souza ; Sergio M. Nunomura; Magno P. Muniz; Ana Paula R. Pereira; Bianca O. Augusto; Giovana B. Gomes; Renata T. Perdomo; Maria Lígia R. Macedo; Simone S. Weber; Rita de Cassia S. Nunomura
Enhanced Larvicidal Activity of New 1,2,4-Oxadiazoles against Aedes aegypti Mosquitos: QSAR and Docking Studies
Aluízio G. da Silva ; Daniela Maria A. F. Navarro ; Geanne K. N. Santos ; Júlio César R. O. F. de Aguiar ; Karla A. de França ; Iris Raquel M. Tébéka ; Janaína V. dos Anjos ; João Bosco P. da Silva ; Luiz A. Kanis ; Rajendra M. Srivastava ; Ricardo Antônio W. Neves Filho ; Mozart N. Ramos
Virtual Screening Based on Ligand and Structure with in vitro Assessment of Neolignans against Trypanosoma cruzi
Mayara S. Maia ; Rodrigo S. Andrade; Julyanne M. S. Sousa; Natália F. Sousa; Gabriela C. S. Rodrigues; Renata P. B. Menezes; Marcelo S. Silva ; Josean F. Tavares; Klinger A. F. Rodrigues; Luciana Scotti; Marcus T. Scotti
Marine Natural Products in the Battle against Dengue, Zika, and Chikungunya Arboviruses
Thayssa S. F. Fagundes ; Thatyana R. A. Vasconcelos ; Fernando M. dos Santos Junior ; Bia F. Rajsfus ; Diego Allonso ; José C. J. M. D. S. Menezes ; Alessandra L. Valverde ; Vinicius R. Campos
Synthesis of Isatins and Oxindoles Derivatives as SARS-CoV-2 Inhibitors Evaluated through Phenotypic Screening with Vero Cells
Cintia M. C. F. Lima; Lúcio H. Freitas-Junior; Carolina B. Moraes; Cecília G. Barbosa; Till Opatz; Mauricio M. Victor
Ursolic Acid Derivatives Down Regulate Inflammatory Mediators
Elaine C. Scherrer; Ydia M. Valadares; Caio C. S. Alves ; Alessandra P. Carli; Bárbara G. R. Fernandes; Paloma E. Carvalho; Karla A. Ramos; Maiara R. Salvador; Jeferson G. da Silva; Fernando S. Silva; Ângelo M. L. Denadai; Sandra B. R. Castro
Synthesis and Anticancer Activity of Homodimeric Morita-Baylis-Hillman Adducts Based on 3-Hydroxyindolin-2-one Core
Maísa C. Coelho ; Aleff Castro ; Tayná R. Olegário ; Rodrigo Cristiano ; Boniek G. Vaz ; Gabriel F. dos Santos ; Lucas S. Machado ; Gardênia C. G. Militão ; Paulo B. N. da Silva ; Mário L. A. A. Vasconcellos ; Claudio G. Lima-Junior
Molecular Modeling Studies of β-Sitosterol Extract from Miconia burchellii Triana (Melastomataceae) from Brazilian Cerrado
Marianna C. Silva ; Vitor S. Duarte; Lóide O. Sallum ; Gracielle O. S. Cunha; Jean M. F. Custodio; Allen G. Oliver; Josana C. Peixoto; Antônio C. S. Menezes; Hamilton B. Napolitano
Unraveling the Metabolomic Profile and Bioactivities of the Paratoid Gland Secretion from Rhinella granulosa
Elcio Daniel S. Barros; Evaldo S. Monção Filho; Mariluce G. Fonseca; Patrícia S. Alves; Antônia Laíres S. Santos; Chistiane M. Feitosa; Dulce Helena S. Silva ; Pedro Mikael S. Costa; Cláudia Pessoa; Carmem D. L. Campos; Cristina A. Monteiro; Mariana Helena Chaves ; Gerardo M. Vieira Júnior
Mitochondria-Targeted Ergosterol Peroxide Derivatives: Synthesis, Anticancer Properties and Their Preliminary Mechanism of Inhibiting MCF-7 Cell Proliferation
Wenkang Ren; Jiale Wu; Jiafeng Wang; Haijun Wang; Yinglong Han; Yu Lin; Ming Bu
Synthesis of Fentanyl Triazole Derivatives and their Affinity for Mu-Opioid and Sigma-1 Receptors
Ruth P. Paulino; Rosemeire B. Alves; Joanna Matalińska; Piotr F. J. Lipiński; Rossimiriam P. Freitas
Four Brazilian Potential Species Almost Unexplored of Connaraceae Family Used Popularly for Diabetes: Chemical Composition and in vitro Activity
Luís Fernando N. A. Paim ; Leonard D. R. Acho; Paulo Roberto dos Santos; Cássio Augusto P. Toledo; Luana Minello; Joicelene Regina L. da Paz; Emerson Lima; Mirian Salvador; Sidnei Moura
Synthesis and Evaluation of the Antileishmanial Activity of Novel Eugenol Analogs Containing 1,2,3-Triazole Fragments against Intracellular Leishmania braziliensis
Roberta S. Evangelista; Larissa C. Pereira; Luciana Â. de Souza; Adilson V. Costa ; Danilo A. da Silva; Fabrício M. de Oliveira; Boniek G. Vaz ; Gustavo C. Bressan; Juliana L. R. Fietto; Róbson R. Teixeira
Papers from 2022
Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
Eliza L. Chazin; Leonardo B. Martins; Marcus Vinícius N. de Souza; Claudia Regina B. Gomes; Ana Cláudia R. da Silva; Marcelly C. Branco; Eladio F. Sanchez; André L. Fuly; Thatyana R. A. Vasconcelos
Diacetate Naphthoquinone Derivatives Tethered to 1,2,3-Triazoles: Synthesis and Cytotoxicity Evaluation in Caco-2 Cells
Dora C. S. Costa ; Adriane S. Francisco; Beatriz V. A. Matuck ; Priscila S. Furtado ; Alana A. S. C. de Oliveira;
Vitor W.-H. Rabelo ; Plínio C. Sathler ; Paula A. Abreu ; Vitor F. Ferreira ; Luiz Cláudio R. P. da Silva ; Fernando C. da Silva
Seleno- and Telluro-Functionalization of Quinones: Molecules with Relevant Biological Application
Pâmella S. Cordeiro ; Ingrid C. Chipoline ; Ruan C. B. Ribeiro ; David R. Pinho; Vitor F. Ferreira ; Fernando C. da Silva ; Luana S. M. Forezi ; Vanessa Nascimento
Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi
Mariana F. C. Cardoso ; Luana S. M. Forezi ; Acácio S. de Souza ; Ana F. M. Faria; Raissa M. S. Galvão; Murilo L. Bello; Fernando C. da Silva ; Robson X. Faria ; Vitor F. Ferreira
Benzophenone Derivatives Showed Dual Anti-Inflammatory and Antiproliferative Activities by Inhibiting COX Enzymes and Promote Cyclin E Downregulation
Laís R. S. Folquitto; Thiago B. de Souza; Jaqueline P. Januario; Isadora M. Nascimento; Brenda T. V. Brandão; Maria E. C. Moreira; Renato O. Horvath; Marcelo H. Santos; Luiz F. L. Coelho; Marcia P. Veloso; Marisi G. Soares; Diogo T. Carvalho ; Marisa Ionta; Daniela A. Chagas-Paula ; Danielle F. Dias
Anti-Zika Virus Effects, Placenta Protection and Chemical Composition of Passiflora edulis Seeds Ethanolic Extract
Jadriane A. Xavier ; Jaqueline C. Santos; Monique A. Vila Nova; Camilla M. Gonçalves; Karen S. C. Borbely ; Keyla S. N. Pires; Flávia A. R. dos Santos ; Iara B. Valentim ; Júnia H. P. Barbosa; Felipe C. da Silva; Josué C. C. Santos ; Danielle R. Pinho; Norberto P. Lopes ; Alexandre U. Borbely ; Marília O. F. Goulart
Synthesis and SARS-CoV-2 3CL Protease Inhibitory Effects of Oxazolidinone Derivatives
Shengxian Zhao ; Chaojie Wang; Yiming Lu; Xin Zhang; Siyu Wu; Hui Mao
Synthesis of Eugenol-Fluorinated Triazole Derivatives and Evaluation of Their Fungicidal Activity
Ângela M. A. Lima; Wenderson T. de Paula; Iris C. H. L. Leite ; Poliana A. R. Gazolla; Lucas M. de Abreu ; Victor R. Fonseca; Wanderson Romão ; Valdemar Lacerda Jr. ; Vagner T. de Queiroz; Róbson R. Teixeira ; Adilson V. Costa
CYP450 Metabolism of a Semisynthetic Naphthoquinone, an Anticancer Drug Candidate, by Human Liver Microsomes
Edna M. A. Costa; Daniel B. Carrão; Jade L. M. Bucci; Anderson R. M. Oliveira; Tallita M. Machado; Vitor F. Ferreira ; Émerson S. Lima ; Marne C. Vasconcellos; Igor R. S. Magalhães
Synthesis of Eugenol-Fluorinated Triazole Derivatives and Evaluation of Their Fungicidal Activity
Ângela M. A. Lima; Wenderson T. de Paula; Iris C. H. L. Leite ; Poliana A. R. Gazolla; Lucas M. de Abreu ; Victor R. Fonseca; Wanderson Romão ; Valdemar Lacerda Jr. ; Vagner T. de Queiroz; Róbson R. Teixeira ; Adilson V. Costa
Volatile Metabolomics from Cashew Leaves: Assessment of Resistance Biomarkers Associated with Black Mold (Pilgeriella anacardii Arx & Müller)
Debora B. de Sousa; Gisele S. da Silva ; Jhonyson A. C. Guedes ; Luiz A. L. Serrano; Marlon V. V. Martins;
Tigressa H. S. Rodrigues ; Edy S. de Brito ; Davila Zampieri; Mary A. S. Lima ; Guilherme J. Zocolo
Online version ISSN 1678-4790 Printed version ISSN 0103-5053
Journal of the Brazilian Chemical Society
JBCS Editorial and Publishing Office
University of Campinas - UNICAMP
13083-970 Campinas-SP, Brazil
Free access